Bimato­prost iso­propyl ester CAS 130209-76-6

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• Prop­er­ties
• Safe­ty Data
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Iden­ti­fi­ca­tion

CAS Number

130209-76-6

Name

imato­prost iso­propyl ester

Syn­onyms

(5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phényl-1-pentén-1-yl]cyclopentyl}-5-hepténoate d’isopropyle [French] [ACD/IUPAC Name]
130209-76-6 [RN]
5-Hep­­tenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)- [ACD/​Index Name]
DEHY­DRO­LA­TANOPROST
Iso­propyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate [ACD/IUPAC Name]
Iso­propyl-(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoat [Ger­man] [ACD/IUPAC Name]
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid iso­propyl ester
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]cyclopentyl]hept-5-enoic acid iso­propyl ester
(Z)-Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-enyl)cyclopentyl)hept-5-enoate
[145773-22-4] [RN]
130273-87-9 [RN]
1334394-97-6 [RN]
145773-22-4 [RN]
17-PHENYL TRI­NOR PGF2α-IPR
17-PHENYL TRI­NOR PGF2α-IPR
17-phenyl tri­nor Prostaglandin F2 ? iso­propyl ester
17-phenyl tri­nor prostaglandin f2?? iso­propyl ester
17-Phenyl tri­nor prostaglandin F2α iso­propyl ester
17-PHENYL TRI­NOR PROSTAGLANDIN F2α ISO­PROPYL ESTER
17-phenyl-tri­nor-PGF2α iso­propyl ester
17-PHENYL­TRI­NORPGF2α-IPR
17-phenyl-tri­nor-Prostaglandin F2α iso­propyl ester
9?,11?,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, iso­propyl ester
Bimato­prost iso­propyl ester
CAS_130209-76-6
iso­propyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]cyclopentyl]hept-5-enoate
iso­propyl 9S,11R,15S-trihydroxy-17-phenyl-18,19,20-trinor-5Z,13E-prostadienoate
ISO­PROPYL PHENYL­HY­DROX­YPEN­TENE DIHY­DROX­Y­CY­CLOPENTYL­HEP­TE­NATE
MFCD00902150
PGF2α,17-phenyl
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]cyclopentyl]hept-5-enoate

SMILES

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCc2ccccc2)O)O)O

Std­InChI

InChI=1S/C26H38O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,16-17,19,21-25,27-29H,4,9,12-15,18H2,1-2H3/b8-3-,17-16+/t21-,22+,23+,24-,25+/m0/s1

Std­InChIKey

JGZR­PRSJSQLF­BO-FWPUOY­­PASA-N

Mol­e­c­u­lar Formula

C₂₆H₃₈O₅

Mol­e­c­u­lar Weight

430.577

MDL Number

MFCD00902150

Prop­er­ties

Appear­ance

Pale yel­low to col­or­less oily liq­uid or pale yel­low to white waxy solid

Safe­ty Data

Sym­bol

Sig­nal Word

Warn­ing

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Bimato­prost iso­propyl ester CAS 130209-76-6

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

99% min

Sol­u­bil­i­ty

Prac­ti­cal­ly insol­u­ble in water, freely sol­u­ble in alco­hol, ace­toni­trile, methanol

Water

≤0.5%

Resid­ual solvent

Ethanol

≤0.5%

n-Hexa­­ne

≤0.029%

Iso­propanol

≤0.5%

Sin­gle Impurity

≤0.5%

Total Impu­ri­ties

≤2.0%

Shelf Life

2 years

Stor­age

Store -10°C for long time, in con­tain­er tight­ly sealed ; Pro­tect from light and moisture.

Known Appli­ca­tion

Bimato­prost is wide­ly used in the cos­met­ic field to pro­mote eye­lash growth. Its mech­a­nism of action and effects are as follows :

Mech­a­nism of Action
Bimato­prost pro­longs the growth phase of eye­lash­es (the active phase in the eye­lash growth cycle) and increas­es the num­ber of hair fol­li­cles, stim­u­lat­ing nat­ur­al eye­lash growth. This mech­a­nism sig­nif­i­cant­ly enhances eye­lash den­si­ty, length, and pigmentation.

Appli­ca­tion Method
It is typ­i­cal­ly applied top­i­cal­ly using a spe­cial appli­ca­tor to place the solu­tion at the base of the upper eye­lash­es (avoid­ing con­tact with the eyes and low­er lash­es). A com­mon rec­om­men­da­tion is to apply it once daily.

Effec­tive­ness
Bimato­prost use gen­er­al­ly starts to show results after 4 – 8 weeks, with opti­mal effects observed at 12 – 16 weeks. Eye­lash­es become notice­ably longer, denser, and dark­er due to increased pig­men­ta­tion, giv­ing them a more promi­nent and defined appearance.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Apnoke Sci­en­tif­ic Lim­it­ed (http://​www​.apnoke​.com/).

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