Chinese Hamster Ovary cell line, CHO-derived human MAN1A1 protein.
Catalytic Activity
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2.
Definition of Enzyme Activity
Measured by its ability to remove alpha -mannose from the high mannose glycan Man-9 under the described conditions.