Recom­bi­nant Human Cyclin-Depen­dent Kinase Inhibitor 2A, Iso­form 1 (rHup16-INK4a) CAS 601-10-1816

Offi­cial Full Name

Recom­bi­nant Human Cyclin-Depen­­dent Kinase Inhibitor 2A, Iso­form 1 (rHup16-INK4a)

CAS Num­ber (Or Wat­son Num­ber for Non-CAS Products)

601-10-1816

Syn­onyms

CDK4I, MTS-1, p16INK4A

Squence

Amino Acid Sequence

MEPAAGSSME PSAD­WLATAA ARGRVEEVRA LLEA­GALP­NA PNSY­GR­RPIQ VMM­MGSAR­VA ELL­LL­H­GAEP NCAD­PATL­TR PVH­DAAREGF LDTLVVLHRA GARLD­VR­DAW GRLPVD­LAEE LGHRD­VARYL RAAAG­GTRGS NHARI­DAAEG PSDIPD

Syn­onyms

CDK4I, MTS-1, p16INK4A

Acces­sion

Gene ID

Sum­ma­ry

Source

Escherichia coli.

Mol­e­c­u­lar Weight

Approx­i­mate­ly 16.5 kDa, a sin­gle non-gly­­co­sy­lat­ed polypep­tide chain con­tain­ing 156 amino acids.

Bio­log­i­cal Activity

No data avail­able.

Appear­ance

Ster­ile Fil­tered White lyophilized (freeze-dried) pow­der.

For­mu­la­tion

Lyophilized from a 0.2 um fil­tered con­cen­trat­ed solu­tion in PBS, pH 7.4.

Endo­tox­in

Less than 1 EU/​ug of rHuP16-INK4a as deter­mined by LAL method.

Recon­sti­tu­tion

We rec­om­mend that this vial be briefly cen­trifuged pri­or to open­ing to bring the con­tents to the bot­tom. Recon­sti­tute in ster­ile dis­tilled water or aque­ous buffer con­tain­ing 0.1 % BSA to a con­cen­tra­tion of 0.1-1.0 mg/​mL. Stock solu­tions should be appor­tioned into work­ing aliquots and stored at ≤ -20 °C. Fur­ther dilu­tions should be made in appro­pri­ate buffered solu­tions.

Sta­bil­i­ty and Storage

Use a man­u­al defrost freez­er and avoid repeat­ed freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as sup­plied.- 1 month, 2 to 8 °C under ster­ile con­di­tions after recon­sti­tu­tion.- 3 months, -20 to -70 °C under ster­ile con­di­tions after recon­sti­tu­tion.

Ref­er­ences

1. Buda G, Mag­gi­ni V, Gal­im­ber­ti S, et al. 2007. Leuk Res, 31 : 569-70.2. Komiya A, Suzu­ki H, Aida S, et al. 1995. Jpn J Can­cer Res, 86 : 622-5.3. Jares P, Fer­nan­dez PL, Nadal A, et al. 1997. Onco­gene, 15 : 1445-53.4. Mori T, Miu­ra K, Aoki T, et al. 1994. Can­cer Res, 54 : 3396-7.

Puri­ty

> 96 % by SDS-PAGE and HPLC analy­ses.

SDS-PAGE

Pack Size

10ug/​100ug/​500ug

Safe­ty Data Sheet (SDS) Down­load

Click to download

Tech­ni­cal Data Sheet (TDS) Down­load

Click to download

Links

This prod­uct is brand­ed by ChemWhat and sold through our web­site and here is the cor­re­spond­ing link Recom­bi­nant Human Cyclin-Depen­­dent Kinase Inhibitor 2A, Iso­form 1 (rHup16-INK4a) on ChemWhat

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