Official Full Name
Recombinant Human Endostatin (rHuEndostatin)
CAS Number (Or Watson Number for Non-CAS Products)
103-13-1816
Synonyms
Squence
Amino Acid Sequence
HSHRDFQPVL HLVALNSPLS GGMRGIRGAD FQCFQQARAV GLAGTFRAFL SSRLQDLYSI VRRADRAAVP IVNLKDELLF PSWEALFSGS EGPLKPGARI FSFDGKDVLR HPTWPQKSVW HGSDPNGRRL TESYCETWRT EAPSATGQAS SLLGGRLLGQ SAASCHHAYI VLCIENSFMT ASKSynonyms
Accession
P39060Gene ID
80781Summary
Source
Molecular Weight
Approximately 20.1 kDa, a single non-glycosylated polypeptide chain containing 183 amino acids (C-terminal fragment of Collagen alpha-1(
XVIII) chain).
Biological Activity
Fully biologically active when compared to standard. The
ED50 as determined by inhibiting the
FGF basic-dependent proliferation of
HUVEC migration is less than 2.0 ug/mL in the presence of Anti-Human Endostatin Polyclonal Antibody.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2 um filtered concentrated solution in
PBS, pH 7.4.
Endotoxin
Less than 1
EU/ug of rHuEndostatin as determined by
LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 %
BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
Purity
> 96 % by
SDS-PAGE and
HPLC analyses.
SDS-PAGE
Pack Size
100ug/500ug
Safety Data Sheet (SDS) Download
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