Recom­bi­nant Human Insulin-like Growth Fac­tor-Bind­ing Pro­tein 5 (rHuIGF-BP5) CAS 105-0125-1816

Offi­cial Full Name

Recom­bi­nant Human Insulin-like Growth Fac­­tor-Bind­ing Pro­tein 5 (rHuIGF-BP5)

CAS Num­ber (Or Wat­son Num­ber for Non-CAS Products)

105-0125-1816

Syn­onyms

Squence

Amino Acid Sequence

LGS­FVH­CEPC DEKALSM­CPP SPLGCELVKE PGCGC­CMT­CA LAEGQSCGVY TER­CAQGLRC LPRQDEEK­PL HALL­H­GRGVC LNEKSYRE­QV KIERD­SRE­HE EPTTSE­MAEE TYSP­KIFRPK HTRISELKAE AVKKDR­RKKL TQSK­FVG­GAE NTAH­PRI­ISA PEM­RQE­SE­QG PCR­RHMEASL QELKA­SPRMV PRAVYLP­NCD RKG­FYKRKQC KPSR­GRKR­GI CWCVD­KYGMK LPG­MEYVDGD FQCHTFDSSN VE

Syn­onyms

Acces­sion

P24593

Gene ID

3488

Sum­ma­ry

Source

Mol­e­c­u­lar Weight

Approx­i­mate­ly 28.6 kDa, a sin­gle non-gly­­co­sy­lat­ed polypep­tide chain con­tain­ing 252 amino acids.

Bio­log­i­cal Activity

Ful­ly bio­log­i­cal­ly active when com­pared to stan­dard. The ED50 as deter­mined by its abil­i­ty to inhib­it IGF-II induced pro­lif­er­a­tion of MCF-7 cells is less than 0.4 ug/​ml, cor­re­spond­ing to a spe­cif­ic activ­i­ty of > 2500 IU/​mg in the pres­ence of 15 ng/​ml of rHuIGF-II.

Appear­ance

Ster­ile Fil­tered White lyophilized (freeze-dried) pow­der.

For­mu­la­tion

Lyophilized from a 0.2 um fil­tered con­cen­trat­ed solu­tion in 10 mM Sodi­um Cit­rate, pH 3.0.

Endo­tox­in

Less than 0.1 EU/​ug of rHuIGF-BP5 as deter­mined by LAL method.

Recon­sti­tu­tion

We rec­om­mend that this vial be briefly cen­trifuged pri­or to open­ing to bring the con­tents to the bot­tom. Recon­sti­tute in ster­ile dis­tilled water or aque­ous buffer con­tain­ing 0.1 % BSA to a con­cen­tra­tion of 0.1-1.0 mg/​mL. Stock solu­tions should be appor­tioned into work­ing aliquots and stored at ≤ -20 °C. Fur­ther dilu­tions should be made in appro­pri­ate buffered solu­tions.

Sta­bil­i­ty and Storage

Use a man­u­al defrost freez­er and avoid repeat­ed freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as sup­plied.- 1 month, 2 to 8 °C under ster­ile con­di­tions after recon­sti­tu­tion.- 3 months, -20 to -70 °C under ster­ile con­di­tions after recon­sti­tu­tion.

Ref­er­ences

Puri­ty

> 96 % by SDS-PAGE and HPLC analy­ses.

SDS-PAGE

Pack Size

5ug/​100ug/​500ug

Safe­ty Data Sheet (SDS) Down­load

Click to download

Tech­ni­cal Data Sheet (TDS) Down­load

Click to download

Links

This prod­uct is brand­ed by ChemWhat and sold through our web­site and here is the cor­re­spond­ing link Recom­bi­nant Human Insulin-like Growth Fac­­tor-Bind­ing Pro­tein 5 (rHuIGF-BP5) on ChemWhat

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