sds page 201 09 3 - Recombinant Human Monokine Induced by Interferon-gamma/CXCL9 (rHuMIG/CXCL9) CAS 201-09-1816

Offi­cial Full Name

Recom­bi­nant Human Monokine Induced by Inter­fer­­on-gam­­ma/CX­CL9 (rHuMIG/​CXCL9)

CAS Num­ber (Or Wat­son Num­ber for Non-CAS Products)

201-09-1816

Syn­onyms

Monokine-like Pro­tein

Squence

region 201 09 1 - Recombinant Human Monokine Induced by Interferon-gamma/CXCL9 (rHuMIG/CXCL9) CAS 201-09-1816

Amino Acid Sequence

TPVVRK­GRCS CIST­NQGTIH LQS­LKDLKQF APSP­SCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRK­SQRSRQK KTT

Syn­onyms

Monokine-like Pro­tein

Acces­sion

Q07325

Gene ID

4283

Sum­ma­ry

CXCL9 is a T-cell chemoat­trac­tant induced by IFN-gam­­ma belong­ing to the CXC chemokine fam­i­ly and it is also known as Monokine induced by gam­ma inter­fer­on (MIG). CXCL9 is close­ly relat­ed to two oth­er CXC chemokines called CXCL10 and CXCL11 and they all elic­it their chemo­tac­tic func­tions by inter­act­ing with the chemokine recep­tor CXCR3. CXCL9 is a cytokine that affects the growth, move­ment, or acti­va­tion state of cells that par­tic­i­pate in immune and inflam­ma­to­ry response and chemo­tac­tic for acti­vat­ed T-cells. Recom­bi­nant human CXCL9 con­tains 103 amino acids which is a sin­gle non-gly­­co­sy­lat­ed polypep­tide chain. The human CXCL9 shares 75 % and 67 % a.a. sequence iden­ti­ty with mouse and rat CXCL9.

Source

Escherichia coli.

Mol­e­c­u­lar Weight

Approx­i­mate­ly 11.7 kDa, a sin­gle non-gly­­co­sy­lat­ed polypep­tide chain con­tain­ing 103 amino acids.

Bio­log­i­cal Activity

Ful­ly bio­log­i­cal­ly active when com­pared to stan­dard. The bio­log­i­cal activ­i­ty deter­mined by a chemo­taxis bioas­say using human periph­er­al blood T-lym­pho­­cytes is in a con­cen­tra­tion range of 10-100 ng/​ml.

Appear­ance

Ster­ile fil­tered white lyophilized (freeze-dried) pow­der.

For­mu­la­tion

Lyophilized from a 0.2 um fil­tered con­cen­trat­ed solu­tion in 20 mM PB, pH 7.4, 50 mM NaCl.

Endo­tox­in

Less than 1 EU/​ug of rHuMIG/​CXCL9 as deter­mined by LAL method.

Recon­sti­tu­tion

We rec­om­mend that this vial be briefly cen­trifuged pri­or to open­ing to bring the con­tents to the bot­tom. Recon­sti­tute in ster­ile dis­tilled water or aque­ous buffer con­tain­ing 0.1 % BSA to a con­cen­tra­tion of 0.1-1.0 mg/​mL. Stock solu­tions should be appor­tioned into work­ing aliquots and stored at ≤ -20°C. Fur­ther dilu­tions should be made in appro­pri­ate buffered solu­tions.

Sta­bil­i­ty and Storage

Use a man­u­al defrost freez­er and avoid repeat­ed freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as sup­plied.- 1 month, 2 to 8 °C under ster­ile con­di­tions after recon­sti­tu­tion.- 3 months, -20 to -70 °C under ster­ile con­di­tions after recon­sti­tu­tion.

Ref­er­ences

Puri­ty

> 97 % by SDS-PAGE and HPLC analy­ses.

SDS-PAGE

sds page 201 09 2 - Recombinant Human Monokine Induced by Interferon-gamma/CXCL9 (rHuMIG/CXCL9) CAS 201-09-1816

Pack Size

5ug/​100ug/​500ug

Safe­ty Data Sheet (SDS) Down­load

Click to download

Tech­ni­cal Data Sheet (TDS) Down­load

Click to download

Links

This prod­uct is brand­ed by ChemWhat and sold through our web­site and here is the cor­re­spond­ing link Recom­bi­nant Human Monokine Induced by Inter­fer­­on-gam­­ma/CX­CL9 (rHuMIG/​CXCL9) on ChemWhat

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