2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinecarboxaldehyde CAS 121660-37-5

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
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Iden­ti­fi­ca­tion

CAS Number

121660-37-5

Name

2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinecarboxaldehyde

Syn­onyms

121660-37-5 [RN]
2-Cyclopropyl-4-(4-fluorophényl)-3-quinoléinecarbaldéhyde [French] [ACD/IUPAC Name]
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarbaldehyde [ACD/IUPAC Name]
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxaldehyde
2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde
2-Cyclopropyl-4-(4-fluorophenyl)-quinoline-3-carbaldehyde
2-Cyclopropyl-4-(4-fluorphenyl)-3-chinolincarbaldehyd [Ger­man] [ACD/IUPAC Name]
3-Quino­­linecar­box­alde­hyde, 2-cyclopropyl-4-(4-fluorophenyl)- [ACD/​Index Name]
[121660-37-5] [RN]
1346597-84-9 [RN]
2-cyclopropan-4-(4-fluorophenyl)-3-quinoline formalde­hyde
2-Cyclopropyl-4-(4-fluorophenyl) -3-quino­­linecar­box­alde­hyde
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinoline-d5 3-Alde­hyde
2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbal
2-Cyclopropyl-4-(4-fluoro-phenyl)-quinoline-3-carbaldehyde
2-cyclopropyl-4-(4-fluorophenyl)QUINOLINE-3-carboxaldehyde
2-Cyclopropyl-4-(4-Fluorophenyl)quinoline-3-Carboxaldehyde (en)
3-QUINO­­LINECAR­BOX­ALDE­HYDE 2-CYCLO­PROPYL-4-(4-FLU­O­ROPHENYL)-
ACMC-1CHZM
AGN-PC-0MW5KG
BR-25327
CTK0H4907
DS-0453
Eth­yl 4-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate [ACD/IUPAC Name]
JAH­BIRPTCX­OGLB-UHF­F­­FAOYSA-N
MFCD09032925 [MDL num­ber]
QA-2520
SCHEMBL244423

SMILES

C1CC1C2=NC3=CC=CC=C3C(=C2C=O)C4=CC=C(C=C4)F

Std­InChI

InChI=1S/C19H14FNO/c20-14-9-7-12(8-10-14)18-15-3-1-2-4-17(15)21-19(13-5-6-13)16(18)11-22/h1-4,7-11,13H,5-6H2

Std­InChIKey

JAH­BIRPTCX­OGLB-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C₁₉H₁₄FNO

Mol­e­c­u­lar Weight

291.319

MDL Number

MFCD09032925

Prop­er­ties

Appear­ance

Off-white or slight­ly yel­low crys­talline powder

Safe­ty Data

Sym­bol

GHS07

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Iden­ti­fi­ca­tion Methods

IR

Puri­ty

99% min

Loss on drying

≤0.45%

Impu­ri­ty I

≤0.08%

Oth­er indi­vid­ual impurity

≤0.1%

Total Impu­ri­ties

≤1%

Shelf Life

2 years

Known Appli­ca­tion

2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde is an organ­ic com­pound pri­mar­i­ly used as an inter­me­di­ate in phar­ma­ceu­ti­cal syn­the­sis.
2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde is an impor­tant inter­me­di­ate in the syn­the­sis of Pitavas­tatin cal­ci­um. Pitavas­tatin cal­ci­um is a statin med­ica­tion pri­mar­i­ly used to low­er cho­les­terol and pre­vent car­dio­vas­cu­lar diseases.

As an inter­me­di­ate, 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde helps to enhance the syn­the­sis effi­cien­cy of Pitavas­tatin cal­ci­um, mak­ing the pro­duc­tion process more effi­cient and con­trol­lable.
The qual­i­ty and puri­ty of the inter­me­di­ate direct­ly affect the final drug’s qual­i­ty. High-qual­i­­ty inter­me­di­ates con­tribute to pro­duc­ing Pitavas­tatin cal­ci­um with high­er puri­ty and few­er side effects.
Choos­ing the appro­pri­ate inter­me­di­ate in the drug syn­the­sis process can min­i­mize unnec­es­sary by-prod­ucts, there­by reduc­ing the final drug’s side effects.
The struc­ture of 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde con­tributes to the phar­ma­co­log­i­cal activ­i­ty of Pitavas­tatin cal­ci­um, mak­ing it more effec­tive in low­er­ing cho­les­terol and pre­vent­ing car­dio­vas­cu­lar diseases.

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Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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