2-(Trimethylsilyl)ethoxymethyl chlo­ride CAS 76513-69-4

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
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Iden­ti­fi­ca­tion

CAS Number

76513-69-4

Name

2-(Trimethylsilyl)ethoxymethyl chlo­ride

Syn­onyms

(2-Chloromethoxyethyl)trimethylsilane
2-(Chlormethoxy)ethylsilan [Ger­man] [ACD/IUPAC Name]
2-(Chloromethoxy)ethylsilane [ACD/IUPAC Name]
2-(Chlorométhoxy)éthylsilane [French] [ACD/IUPAC Name]
[2-(chloromethoxy)ethyl]trimethylsilane
2-(Trimethylsilyl)ethoxymethyl chlo­ride
278-483-4 [EINECS]
76513-69-4 [RN]
Chloromethyl 2-trimethyl­si­­lylethyl ether
MFCD00009919 [MDL num­ber]
SEM-chlo­ride
SEM-Cl
Silane, [2-(chloromethoxy)ethyl]trimethyl- [ACD/​Index Name]

(2-(chloromethoxy)ethyl)trimethylsilane
[76513-69-4] [RN]
138786-65-9 [RN]
2- ethoxymethylchlo­ride
2-(chloromethoxy)ethyl-trimethylsilane
2-(Chloromethoxy)ethyltrimethylsilane (sta­bi­lized with Diiso­propy­lethy­lamine)
2-(Chloromethoxyethyl)trimethyl silane
2-(Chloromethoxyethyl)trimethyl silane|SEM-Cl
2-(Trimethsilyl)-ethoxymethyl chlo­ride
2-(Trimethylsilyl)ethoxymethyl Chlo­ride (SEM-Cl)
2-(Trimethylsilyl)ethoxymethylchloride
2-(trimethysilyl)-ethoxymethyl chlo­ride
2-Chloroethoxy Methyl trimethyl silane
2-Chloromethyl 2-(trimethylsilyl)ethyl ether
95%
FS-3821
OS-7574
SEM­Cl
sta­bi­lized

SMILES

C[Si](C)(C)CCOCCl

Std­InChI

InChI=1S/C6H15ClOSi/c1-9(2,3)5-4-8-6-7/h4-6H2,1-3H3

Std­InChIKey

BPXKZEM­BEZGUAH-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C₆H₁₅ClOSi

Mol­e­c­u­lar Weight

166.721

EINECS

278-483-4

Beil­stein Reg­istry Number

3587289

MDL Number

MFCD00009919

Prop­er­ties

Appear­ance

Colour­less to light yel­low liquid

Safe­ty Data

Sym­bol

GHS02, GHS05

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Puri­ty

95% min

Water

≤2.0%

Sin­gle Impurity

≤3.0%

Total Impu­ri­ties

≤5.0%

Shelf Life

2 years

Known Appli­ca­tion

2-(Trimethylsilyl)ethoxymethyl chlo­ride CAS 76513-69-4 (SEM-Cl) is an organosil­i­con com­pound com­mon­ly used as a pro­tect­ing group in organ­ic synthesis. 

SEM-Cl is fre­quent­ly used as a pro­tect­ing group in organ­ic syn­the­sis, par­tic­u­lar­ly for pro­tect­ing hydrox­yl (-OH) and amino (-NH2) groups. The use of pro­tect­ing groups can pre­vent these func­tion­al groups from under­go­ing unwant­ed reac­tions dur­ing the syn­the­sis process, there­by increas­ing the selec­tiv­i­ty and effi­cien­cy of the synthesis.

In the syn­the­sis of com­plex organ­ic mol­e­cules, SEM-Cl can be used to tem­porar­i­ly pro­tect cer­tain func­tion­al groups. Once oth­er parts of the syn­the­sis are com­plet­ed, the pro­tect­ing group can be removed under spe­cif­ic con­di­tions to restore the orig­i­nal func­tion­al group.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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