Dapagliflozin CAS 461432-26-8

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
• Links
• Quick Inquiry

Iden­ti­fi­ca­tion

CAS Number

461432-26-8

Name

Dapagliflozin

Syn­onyms

(1S)-1,5-Anhydro-1-[4-chlor-3-(4-ethoxybenzyl)phenyl]-D-glucitol [Ger­man] [ACD/IUPAC Name]
(1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol [ACD/IUPAC Name]
(1S)-1,5-Anhydro-1-[4-chloro-3-(4-éthoxybenzyl)phényl]-D-glucitol [French] [ACD/IUPAC Name]
(2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol
1ULL0QJ8UC
461432-26-8 [RN]
Dapagliflozin [INN] [USAN] [Wiki]
dapaglifloz­i­na [Span­ish] [INN]
dapagliflozine [French] [INN]
dapaglifloz­inum [Latin] [INN]
D-Glu­­ci­­tol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)- [ACD/​Index Name]
Farx­i­ga [Trade name]
Forx­i­ga [Trade name]
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
(1S)-1,5-anhydro-1-c-4-chloro-3-(4-ethoxyphenyl)methylphenyl-d-glucitol
(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyl-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-methylol-tetrahydropyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hyd roxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hydroxymethyl)tetrahy
(2S,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol
[461432-26-8] [RN]
1204219-80-6 [RN]
BMS 512148
BMS 512148 ; BMS-512148
BMS512148
BMS-512148 ;BMS512148 ;BMS 512148
BMS-512148|Farxiga®|Forxiga®
dapagliflozin ????????????
dapagliflozin d5
dapagliflozin 达格列净 [Chi­nese]
Dapagliflozin ;BMS 512148
Dapagliflozin|BMS 512148
dapagliflozin-d5
Farx­i­ga®
Forx­i­ga®
https://​www​.ebi​.ac​.uk/​c​h​e​m​b​l​/​c​o​m​p​o​u​n​d​r​e​p​o​r​t​c​a​r​d​/​C​H​E​M​B​L​4​2​9​9​10/
MFCD13182359 [MDL num­ber]
UNII :1ULL0QJ8UC
UNII-1UL­L0QJ8UC

SMILES

CCOc1ccc(cc1)Cc2cc(ccc2Cl)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

Std­InChI

InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1

Std­InChIKey

JVHXJT­B­JCF­BINQ-ADAARD­CZSA-N

Mol­e­c­u­lar Formula

C₂₁H₂₅ClO₆

Mol­e­c­u­lar Weight

408.873

EINECS

639-683-0

MDL Number

MFCD13182359

Prop­er­ties

Appear­ance

white to gray­ish white powder

Struc­ture

Struc­ture of Dapagliflozin CAS 461432-26-8

Safe­ty Data

Sym­bol

GHS07, GHS08, GHS09

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Iden­ti­fi­ca­tion Methods

Heavy Met­als

NMT 10ppm

Water

NMT 2%

Residue on Ignition

NMT 0.5%

Shelf Life

2 years

Stor­age

Known Appli­ca­tion

Dapagliflozin is a sodi­um-glu­­cose co-tran­s­­porter 2 inhibitor (SGLT2i) and a new type of oral hypo­glycemic drug. It can inhib­it SGLT2 activ­i­ty, inhib­it prox­i­mal renal tubu­lar sodi­um-glu­­cose reab­sorp­tion, pro­mote uri­nary glu­cose excre­tion, and there­by reduce blood glu­cose concentration.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

Quick Inquiry

Fill out our inquiry form and one of our experts will be in touch with you shortly.