L-(+)-Selenomethionine CAS 3211-76-5

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions and Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

3211-76-5

Name

L-(+)-Selenomethionine

Syn­onyms

(2R)-2-amino-4-(methylselanyl)butanoic acid (2R)-2-amino-4-(methylseleno)butanoic acid (2S)-2-Amino-4-(methylseleno)butanoic acid butanoic acid, 2-amino-4-(methylseleno)-, (2R)- L-(+)-Selenomethionine (S)-(+)-2-Amino-4-(methylseleno)butanoic acid

Mol­e­c­u­lar Structure

SMILES

O=C(O)[C@H](N)CC[Se]C

Std­InChI

InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

Std­InChIKey

RJFAYQI­BOAG­BLC-SCSAIB­SYSA-N

Mol­e­c­u­lar Formula

C5H11NO2Se

Mol­e­c­u­lar Weight

196.11

MDL Number

MFCD00037210

Prop­er­ties

Appear­ance

Off-white to white pow­der

Sol­u­bil­i­ty

50mg in 1ml water clear sol­u­ble

Melt­ing Point

265 ºC

Boil­ing Point

320.78 °C at 760 mmHg

Flash Point

147.803 °C

Safe­ty Data

Sym­bol

GHS06, GHS08, GHS09

Sig­nal Word

Dan­ger

Haz­ard Statements

H301-H331-H373-H410

Pre­cau­tion­ary Statements

P261-P273-P301 + P310-P311-P501

Haz­ard Codes (Europe)

T,N

Risk State­ments (Europe)

23/25-33-50/53

Safe­ty State­ments (Europe)

20/21-28-45-60-61

RIDADR

UN 3283 6.1/PG 2 

WGK Germany

3 

RTECS

EK7713840

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our L-(+)-Selenomethionine CAS 3211-76-5

Assay

98.0%-102.0%

Iden­ti­fi­ca­tion Method

HNMR, MS, HPLC

Opti­cal rotation20℃/D(C=1, 1N HCl)

+16.5°~+20°

D-Iso­mer content

0.05% max

Arsenic

1 ppm max

Cad­mi­um

1 ppm max

Mer­cury

0.1 ppm max

Lead

3 ppm max

Water

0.5% max

Biochem/​physiol Actions

Selenome­thio­n­ine dis­plays antiox­i­dant activ­i­ty and has been shown to increase the activ­i­ty of glu­tathione per­ox­i­dase in endothe­lial cells. Glu­tathione per­ox­i­dase pro­tects cells from oxida­tive dam­age, such as DNA strand breaks, muta­tions and inter­fer­ence with pro­tein tyro­­sine-based sig­nal­ing and oth­er pro­tein func­tions due to for­ma­tion of 3-nitroty­ro­­sine, caused by exces­sive per­ox­yni­trite. Selenome­thio­n­ine admin­is­tra­tion to can­cer cell lines (MCF-7/S breast car­ci­no­ma, DU-145 prostate can­cer cells and UACC-375 melanoma) results in apop­tot­ic cell death and aber­rant mito­sis. These human tumor cell lines exhib­it­ed dose-depen­­dent growth inhi­bi­tion by selenome­thio­n­ine in the micro­mo­lar range (45 to 130 μM), while growth inhi­bi­tion of nor­mal fibrob­lasts required 1 mM selenome­thio­n­ine.

Pro­duc­tiv­i­ty

1kg/​month

Stor­age Tempeature

Trans­port at room tem­per­a­ture, long-term preser­va­tion at 0 ~ 5°

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our RandD com­pa­ny Apnoke Sci­en­tif­ic Ltd(http://​www​.apnoke​.com/), and here is the cor­re­spond­ing linkhttp://​www​.apnoke​.com/​l​-​s​e​l​e​n​o​m​e​t​h​i​o​n​i​n​e​-​c​a​s​-​3​2​1​1​-​7​6​-​5​-2/

Quick Inquiry

Fill out our inquiry form and one of our experts will be in touch with you short­ly (Please change screen to hor­i­zon­tal for com­plete brows­ing if you are check­ing Wat­son on your mobile phone).  andD pur­pose. It may be tox­ic or haz­ardous, and should be han­dled only by qual­i­fied indi­vid­u­als trained in lab­o­ra­to­ry pro­ce­dures. The buy­er will be respon­si­ble to warn and inform any per­son that may be in con­tact with the prod­uct of the poten­tial risks and haz­ards, as well as to ensure that pur­chase, use and dis­pos­al of the prod­uct com­ply with local laws and regulations.