structure of Lefamulin CAS 1061337 51 6 - Lefamulin CAS 1061337-51-6

Iden­ti­fi­ca­tion

CAS Number

1061337-51-6

Name

Lefa­mulin

Syn­onyms

(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate [ACD/IUPAC Name]
(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl-{[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetat [Ger­man] [ACD/IUPAC Name]
{[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]sulfanyl}acétate de (1S,2R,3S,4S,6R,7R,8R,14R)-3-hydroxy-2,4,7,14-tétraméthyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tétradéc-6-yle [French] [ACD/IUPAC Name]
1061337-51-6 [RN]
21904A5386
Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester [ACD/​Index Name]
lefa­muli­na [Span­ish] [INN]
léfa­mu­line [French] [INN]
lefa­mulinum [Latin] [INN]
Xen­le­ta [Trade name]
[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanylacetate
1061337-51-6 (free base)
1061872-97-6 [RN]
62B
lefa­muli­na
léfa­mu­line
lefa­mulinum
MFCD28963989
UNII :21904A5386
UNII-21904A5386
лефамулин [Russ­ian]
ليفامولين [Ara­bic]
来法莫林 [Chi­nese]
Less…
Val­i­dat­ed by Experts, Val­i­dat­ed by Users, Non-Val­i­­dat­ed, Removed by Users
9849 [DBID]
BC-3781 [DBID]
UNII-61H04Z5F9K [DBID]

SMILES

C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C

Std­InChI

InChI=1S/C28H45NO5S/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27+,28+/m1/s1

Std­InChIKey

KPVIXBKI­JXZQJX-FCEONZPQSA-N

Mol­e­c­u­lar Formula

C28H45NO5S

Mol­e­c­u­lar Weight

507.726

MDL Number

MFCD28963989

Prop­er­ties

Appear­ance

sol­id

Struc­ture

structure of Lefamulin CAS 1061337 51 6 - Lefamulin CAS 1061337-51-6
struc­ture of Lefa­mulin CAS 1061337-51-6

Safe­ty Data

Sym­bol

Sig­nal Word

Warn­ing

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Water

Loss on Drying

Residue on Ignition

Sin­gle Impurity

Total Impu­ri­ties

Shelf Life

2 years

Stor­age

Under room tem­per­a­ture away from light

Known Appli­ca­tion

Lefa­mulin is a pleu­ro­mu­tilin class antibi­ot­ic used to treat com­­mu­ni­­ty-acquired bac­te­r­i­al pneu­mo­nia (CABP) in adult patients caused by sus­cep­ti­ble microor­gan­isms. To min­i­mize the emer­gence of resis­tant bac­te­ria and pre­serve the effi­ca­cy of Lefa­mulin and oth­er antibi­otics, it should be used only for the treat­ment or pre­ven­tion of con­firmed or high­ly sus­pect­ed bac­te­r­i­al infections.

Gen­er­al View of Documents

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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