Structure of m7GpppNm CAS UENA 0197 - m7GpppNm CAS UENA-0197

Iden­ti­fi­ca­tion

CAS Number

UENA-0197

Name

m7GpppNm

Syn­onyms

cap 1

Prop­er­ties

Safe­ty Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our m7GpppNm CAS UENA-0197

Appli­ca­tion

In the cell, the cap 0 struc­ture is essen­tial for effi­cient trans­la­tion of the mRNA that car­ries the cap. An addi­tion­al methy­la­tion on the 2′O posi­tion of the ini­ti­at­ing nucleotide gen­er­ates Cap 1, or refers to as m7GpppNm, where Nm denotes any nucleotide with a 2′O methy­la­tion. Cap 1 or m7GpppNm has been shown to be impor­tant in evad­ing the cel­lu­lar innate immune response in vivo. The third gen­er­a­tion of cap struc­ture, co-tran­scrip­­tion­al cap­ping, cap­ping effi­cien­cy 95%

This prod­uct is devel­oped by our R&D com­pa­ny Wat­son Bio Ltd (https://​www​.wat​son​-bio​.com/).

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