Mesalazine//Me­salamine//5-Aminos­al­i­cylic acid(5-ASA) CAS 89-57-6

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
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Iden­ti­fi­ca­tion

CAS Number

89-57-6

Name

Mesalazine//Me­salamine//5-Aminos­al­i­­cylic acid(5-ASA) CAS 89-57-6

Syn­onyms

201-919-1
[EINECS]
2090421
[Beil­stein]
5-Amino-2-hydrox­­y­ben­­zoesäure
[Ger­man]
[ACD/IUPAC Name]
5-Amino-2-hydrox­­y­ben­­zoic acid
[ACD/IUPAC Name]
5-AS
5-ASA
89-57-6
[RN]
Acide 5-amino-2-hydrox­­y­ben­­zoïque
[French]
[ACD/IUPAC Name]
Asa­colon
Ben­zoic acid, 5-amino-2-hydroxy-
[ACD/​Index Name]
Canasa
[Trade name]
Lial­da
[Trade name]
Mesacol
Mesalamine
[USP]
[USAN]
[Trade name]
Mesalaz­i­na
[Span­ish]
Mesalazine
[Wiki] link-icon
[INN]
[BAN]
Mesalaz­inum
[Latin]
MFCD00007877
[MDL num­ber]
Pen­tasa
[Trade name]
Rowasa
[Trade name]
Salo­falk
[Trade name]
Saloz­i­nal
ZR CQ DVQ
[WLN]

SMILES

Nc1ccc(O)c(C(=O)O)c1

Std­InChI

InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

Std­InChIKey

KBOPZPXVL­CULAV-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C7H7NO3

Mol­e­c­u­lar Weight

153.137

EINECS

201-919-1

Beil­stein Reg­istry Number

2090421

MDL Number

MFCD00007877

Prop­er­ties

Appear­ance

White pow­der

Melt­ing Point

275-280 °C

Safe­ty Data

Sym­bol

GHS07

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

Per­son­al Pro­tec­tive Equipment

dust mask type N95 (US), Eye­shields, Gloves

RIDADR 

NONH for all modes of transport

WGK Germany

2

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Mesalazine//Me­salamine//5-Aminos­al­i­­cylic acid(5-ASA) CAS 89-57-6

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Stan­dard

JP, CP , USP

Puri­ty

99% min

Shelf Life

2 years

Stor­age

Under room tem­per­a­ture away from light

Pro­duc­tiv­i­ty

1MT/​month

Known Appli­ca­tion

Mesalazine is the active com­po­nent of sul­fasalazine (SASP), respon­si­ble for its ther­a­peu­tic effects in treat­ing ulcer­a­tive col­i­tis and Crohn’s dis­ease. Its mech­a­nism involves sup­press­ing inflam­ma­tion in the intesti­nal mucosa by tar­get­ing crit­i­cal inflam­ma­to­ry path­ways.
Treat­ment of Ulcer­a­tive Col­i­tis : Effec­tive­ly alle­vi­ates symp­toms such as abdom­i­nal pain, diar­rhea, and rec­tal bleed­ing.
Main­te­nance of Remis­sion : Helps pre­vent relaps­es in patients with ulcer­a­tive col­i­tis.
Man­age­ment of Crohn’s Dis­ease : Used for mild to mod­er­ate cas­es of Crohn’s dis­ease as part of a com­pre­hen­sive treat­ment plan.

Reg­u­la­to­ry Approvals

Approved by China’s Nation­al Med­ical Prod­ucts Admin­is­tra­tion (NMPA). Now is active­ly pur­su­ing EU Cer­tifi­cate of Suit­abil­i­ty (CEP) and Drug Mas­ter File (DMF) reg­is­tra­tion in Japan.

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd (https://​www​.cam​ing​.com/).

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