Identification

CAS Number

89-57-6

Name

Mesalazine//Mesalamine//5-Aminosalicylic acid(5-ASA) CAS 89-57-6

Synonyms

201-919-1
[EINECS]
2090421
[Beilstein]
5-Amino-2-hydroxybenzoesäure
[German]
[ACD/IUPAC Name]
5-Amino-2-hydroxybenzoic acid
[ACD/IUPAC Name]
5-AS
5-ASA
89-57-6
[RN]
Acide 5-amino-2-hydroxybenzoïque
[French]
[ACD/IUPAC Name]
Asacolon
Benzoic acid, 5-amino-2-hydroxy-
[ACD/Index Name]
Canasa
[Trade name]
Lialda
[Trade name]
Mesacol
Mesalamine
[USP]
[USAN]
[Trade name]
Mesalazina
[Spanish]
Mesalazine
[Wiki] link-icon
[INN]
[BAN]
Mesalazinum
[Latin]
MFCD00007877
[MDL number]
Pentasa
[Trade name]
Rowasa
[Trade name]
Salofalk
[Trade name]
Salozinal
ZR CQ DVQ
[WLN]

SMILES

Nc1ccc(O)c(C(=O)O)c1

StdInChI

InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

StdInChIKey

KBOPZPXVLCULAV-UHFFFAOYSA-N

Molecular Formula

C7H7NO3

Molecular Weight

153.137

EINECS

201-919-1

Beilstein Registry Number

2090421

MDL Number

MFCD00007877

Properties

Appearance

White powder

Melting Point

275-280 °C

Safety Data

Symbol

exclamation-mark-jpgGHS07

Signal Word

Warning

Hazard statements

H315,H317,H319,H335

Precautionary Statements

P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

RIDADR 

NONH for all modes of transport

WGK Germany

2

Specifications and Other Information of Our Mesalazine//Mesalamine//5-Aminosalicylic acid(5-ASA) CAS 89-57-6

Identification Methods

HNMR, HPLC

Standard

JP, CP , USP

Purity

99% min

Shelf Life

2 years

Storage

Under room temperature away from light

Productivity

1MT/month

Known Application

Mesalazine is the active component of sulfasalazine (SASP), responsible for its therapeutic effects in treating ulcerative colitis and Crohn’s disease. Its mechanism involves suppressing inflammation in the intestinal mucosa by targeting critical inflammatory pathways.
Treatment of Ulcerative Colitis: Effectively alleviates symptoms such as abdominal pain, diarrhea, and rectal bleeding.
Maintenance of Remission: Helps prevent relapses in patients with ulcerative colitis.
Management of Crohn’s Disease: Used for mild to moderate cases of Crohn’s disease as part of a comprehensive treatment plan.

Regulatory Approvals

Approved by China’s National Medical Products Administration (NMPA). Now is actively pursuing EU Certificate of Suitability (CEP) and Drug Master File (DMF) registration in Japan.

This product is developed by our R&D company Caming Pharmaceutical Ltd (https://www.caming.com/).

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