Mir­taza­p­ine CAS 61337-67-5 (85650-52-8)

Iden­ti­fi­ca­tion

CAS Number

61337-67-5 or 85650-52-8

Name

Mir­taza­p­ine

Syn­onyms

2-Methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine 2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin 2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin 2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine 2-Méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine Avan­za mir­taza­p­ina mir­taza­p­inum Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- Remeron Zispin (14bR)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine (rs)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino-(2,1-a)pyrido(2,3-c)(2)benzazepine 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c](2)benzazepine 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8(13),9,11,16,18-hexaene 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8(13),9,11,15,17-hexaene 6-AZA­­MI­ANSERIN Aza­mi­anserin Mepirza­pin mepirzepine Mir­taza­nine Mir­tazepine Mir­tazip­ine Norset Promyr­til Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (±)- Remergil Remer­gon Remeron Rex­er

Mol­e­c­u­lar Structure

SMILES

CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

Std­InChI

InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3

Std­InChIKey

RON­ZA­­EM­N­M­FQXRA-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C17H19N3

Mol­e­c­u­lar Weight

265.35

MDL Number

MFCD00865427

EINECS

288-060-6

Prop­er­ties

Appear­ance

A white or almost white crys­talline pow­der

Sol­u­bil­i­ty

Freely sol­u­ble in methanol and in toluene, sol­u­ble in eth­yl­ether, spar­ing­ly sol­u­ble in hexa­ne, prac­ti­cal­ly insol­u­ble in water.

Safe­ty Data

Per­son­al Pro­tec­tive Equipment

Eye­shields, Gloves, type N95 (US), type P1 (EN143) res­pi­ra­tor fil­ter

WGK Germany

3 

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Mir­taza­p­ine CAS 61337-67-5 (85650-52-8)

Stan­dard

USP

Iden­ti­fi­ca­tion

IR

Assay

98%-102% (anhy­drate sub­stance)

Water

1.0%-3.5%

Residue on Ignition

0.1% max

Heavy Met­als

10ppm max

Resid­ual Solvents

Dimethyl sul­fox­ide : 880ppm max Tetrahy­dro­fu­ran : 720ppm max Toluene : 890ppm max Chlo­ro­form : 60ppm max N-hep­­­tane : 500ppm max Ethanol : 5000ppm max

Impu­ri­ties

Impu­ri­ty A : 0.10% max Impu­ri­ty B : 0.10% max Impu­ri­ty C : 0.10% max Impu­ri­ty D : 0.10% max Impu­ri­ty E : 0.10% max Indi­vid­ual unspec­i­fied impu­ri­ty : 0.10% max Total impu­ri­ties : 0.50% max

Pack­age

25kg/​drum

Man­u­fac­tur­ing Capacity

1 MT/​year

Stor­age

Under room temperature,away from light

Appli­ca­tion

Mir­taza­p­ine (brand names : Avan­za (AU, NZ), Axit (AU), Mir­taz (IN, IE†), Mir­ta­zon (AU), Remeron (AU, CA, HK, IL, NZ†, RU, SG, ZA, US), Zispin (IE, UK); where † indi­cates dis­con­tin­ued prod­ucts) is a nora­dren­er­gic and spe­cif­ic sero­ton­er­gic anti­de­pres­sant (NaS­SA) that was intro­duced by Organon Inter­na­tion­al in the Unit­ed States in 1996 and is used pri­mar­i­ly in the treat­ment of depres­sion. It is also com­mon­ly used as an anx­i­olyt­ic, hyp­not­ic, antiemet­ic and appetite stim­u­lant. In terms of struc­ture, mir­taza­p­ine can also be clas­si­fied as a tetra­cyclic anti­de­pres­sant (TeCA).

Wat­­son-Int Link

http://​wat​son​-int​.com/​M​i​r​t​a​z​a​p​i​n​e​_​C​A​S​_​6​1​3​3​7​-​6​7​-​5​_​8​5​6​5​0​-​5​2​-​8​.​h​tml