MPC//2-Methacry­loy­loxyethyl Phos­pho­ryl­choline CAS 67881-98-5

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
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Iden­ti­fi­ca­tion

CAS Number

67881-98-5

Name

MPC//2-Methacry­loy­loxyethyl Phosphorylcholine

Syn­onyms

2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phos­phate[ACD/IUPAC Name]
2-(Methacryloyloxy)ethyl-2-(trimethylammonio)ethylphosphat[German][ACD/IUPAC Name]
2-methacry­loy­loxyethyl phos­pho­ryl­choline
Ethanamini­um, 2-[[hydroxy[2-[(2-methyl-1-oxo-2-propen-1-yl)oxy]ethoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt[ACD/​Index Name]
MFCD11112180[MDL num­ber]
MPC
Phos­phate de 2-(méthacryloyloxy)éthyle et de 2-(triméthylammonio)éthyle[French][ACD/IUPAC Name]
2-(2-methyl-1-oxoprop-2-enoxy)ethyl 2-(trimethylammonio)ethyl phos­phate
2-(2-methyl-1-oxoprop-2-enoxy)ethyl 2-trimethy­lam­­mo­nioethyl phos­phate
2-(2-methylprop-2-enoyloxy)ethyl 2-(trimethylazaniumyl)ethyl phos­phate
2-(2-methylprop-2-enoyloxy)ethyl 2-trimethy­lam­­mo­nioethyl phos­phate
2-(2-methylprop-2-enoyloxy)ethyl 2-trimethy­laza­­ni­umylethyl phos­phate
2-(Methacryloyloxy)ethyl (2-(trimethylammonio)ethyl) phos­phate
2-methacry­loy­loxyethyl 2-trimethy­lam­­mo­nioethyl phos­phate
2-methacry­loy­loxyethylphos­pho­ryl­­choline
2-Moe
2-Moep
2-{[2-(trimethylamino)ethyl]oxyphosphinyl}ethyl 2-methyl­prop-2-enoate
3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium,4-hydroxy-N,N,N,10-tetramethyl-9-oxo-, inner salt, 4-oxide
Ethanamini­um, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydrox­ide, inner salt
pEthanamini­um, 2-((hydroxy(2-((2-methyl-1-oxo-2-propenyl)oxy)ethoxy)phosphinyl)oxy)-N,N,N-trimethyl-, hydrox­ide, inner salt
TRIMETHYL[2-({2-[(2-METHYL­PROP-2-ENOYL)OXY]ETH­YL PHOS­PHO­NA­TO}OXY)ETH­YL]AZA­NI­UM

SMILES

C=C(C)C(=O)OCCOP(=O)([O-])OCC[N+](C)(C)C

Std­InChI

InChI=1S/C11H22NO6P/c1-10(2)11(13)16-8-9-18-19(14,15)17-7-6-12(3,4)5/h1,6-9H2,2-5H3

Std­InChIKey

ZSZRUEAFVQITHH-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C11H22NO6P

Mol­e­c­u­lar Weight

295.272

MDL Number

MFCD11112180

Prop­er­ties

Appear­ance

White to almost white Powder

Safe­ty Data

Sym­bol

GHS07

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

RIDADR 

NONH for all modes of transport

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our MPC//2-Methacry­loy­loxyethyl Phos­pho­ryl­choline CAS 67881-98-5

Descrip­tion

2-methacry­loy­loxyethyl phos­pho­ryl­choline (MPC), con­tain­ing a phos­pho­ryl­choline group in the side chain is a suit­able monomer to mim­ic the phos­pho­lipid polar groups con­tained with cell mem­branes. MPC block copoly­mers are bio­com­pat­i­ble and hydro­scop­ic in nature ; it shows desir­able inter­ac­tion with liv­ing tissues.

Per­for­mance

Break­ing the bound­ary between inor­gan­ic mate­ri­als and organ­ic bod­ies with excel­lent bio­com­pat­i­bil­i­ty. It has excel­lent human affin­i­ty, bio­com­pat­i­bil­i­ty and anti­co­ag­u­lant prop­er­ties. It is a very impor­tant med­ical mate­r­i­al and is wide­ly used in organ trans­plan­ta­tion, arti­fi­cial blood ves­sels and heart stents to enhance human affin­i­ty, reduce rejec­tion reac­tions, pre­vent throm­bo­sis and pro­long ser­vice life.

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

97% min

Shelf Life

2 years

Stor­age

Store at -20℃ for long time, Avoid hygro­scop­ic effects.

Known Appli­ca­tion

MPC poly­mers are syn­thet­ic phos­pho­lipid poly­mers with zwit­te­ri­on­ic phos­pho­ryl­choline (PC) head groups, which can form cell-mem­brane-like struc­tures on var­i­ous mate­r­i­al sur­faces. This spe­cial sur­face struc­ture has a unique capac­i­ty to pre­vent non­spe­cif­ic pro­tein adsorp­tion (NPA) and thus bio­foul­ing by the adsorp­tion of bio­mol­e­cules, cells, and oth­er bio­log­i­cal enti­ties.
1.Preparation of hydro­gels for use as con­tact lens mate­ri­als and wound dress­ing.
2.Production of poly­mer­ic micelles and nanopar­ti­cles for drug deliv­ery.
3.Synthesis of poly­mer coat­ings for med­ical devices to pre­vent blood clot­ting and bac­te­r­i­al adhe­sion.
4.Use as a monomer to pre­pare poly­mer-mod­­i­­fied antifoul­ing sil­i­cone hydro­gel con­tact lens­es. The addi­tion of MPC forms a cell mem­brane-like struc­ture on the con­tact lens and helps to pre­vent cell and bac­te­r­i­al adhe­sion on the surface.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd (https://​www​.cam​ing​.com/).

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