Pazopanib hydrochlo­ride CAS 635702-64-6

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions andamp ; Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

635702-64-6

Name

Pazopanib hydrochlo­ride

Syn­onyms

5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide hydrochlo­ride (1:1) [ACD/IUPAC Name] 5-({4-[(2,3-Diméthyl-2H-indazol-6-yl)(méthyl)amino]-2-pyrimidinyl}amino)-2-méthylbenzènesulfonamide, chlorhy­drate (1:1) [French] [ACD/IUPAC Name] 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzolsulfonamidhydrochlorid (1:1) [Ger­man] [ACD/IUPAC Name] 635702-64-6 [RN] Ben­zene­sul­fon­amide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochlo­ride (1:1) [ACD/​Index Name] GW786034B GW-786034B Pazopanib Hydrochlo­ride [USAN] Votri­ent [Trade name] [635702-64-6] 444731-52-6 [RN] 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide hydrochlo­ride 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide mono­hy­drochlo­ride 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide hydrochlo­ride 5-[[4-[(2, 3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2- methylbenzenesulfonamide;hydrochloride 5-[[4-[(2,3-dimethyl-6-indazolyl)-methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide hydrochlo­ride 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide and hydron and chlo­ride 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride 5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide HCl 5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide hydrochlo­ride Armala GW 786034 GW786034 GW786034;Votrient;Armala ;GW 786034 ;GW-786034 GW786034GW786034, VOTRI­ENT HYDRO­GEN PAZOPANIB CHLO­RIDE MFCD12546138 [MDL num­ber] Pazopanib Pazopanib (GW-786034) Pazopanib (Hydrochlo­ride) Pazopanib HCL Pazopanib HCl (GW786034 HCl) pazopanib mono­hy­drochlo­ride Pazopanib, Votri­ent, GW786034B, GW 786034, GW-786034 UNII :33Y9ANM545 UNII-33Y9AN­M545

Mol­e­c­u­lar Structure

SMILES

Cc1ccc(cc1S(=O)(=O)N)Nc2nccc(n2)N(C)c3ccc4c(n(nc4c3)C)C.Cl

Std­InChI

InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H

Std­InChIKey

MQHIQUBXF­­FAOMK-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C21H23N7O2S.HCl

Mol­e­c­u­lar Weight

473.98

Prop­er­ties

Appear­ance

White to off-white pow­der

Safe­ty Data

WGK Germany

3 

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Pazopanib hydrochlo­ride CAS 635702-64-6

Stan­dard

Enter­prise stan­dard

Iden­ti­fi­ca­tion Methods

HPLC,XRD

Puri­ty

99%min

Heavy Met­als

10 ppm max

Loss on Drying

0.5% max

Residue on Ignition

0.2% max

Sin­gle Impurity

0.2% max

Total Impu­ri­ties

0.5% max

Pack­age

Accord­ing to cus­tomer require­ments to pack­ag­ing

Man­u­fac­tur­ing Capacity

KG Scale

Stor­age

Under room tem­per­a­ture away from light

Appli­ca­tion

Palazepine Hydrochlo­ride is a nov­el type of oral angio­gen­e­sis inhibitor that can inter­fere with the angio­gen­e­sis required for the sur­vival and growth of stub­born tumors, tar­get­ing the role of vas­cu­lar endothe­lial growth fac­tor recep­tor (VEG­FR), by inhibit­ing the new blood sup­ply to the tumor Angio­gen­e­sis and work. Suit­able for the treat­ment of advanced renal cell car­ci­no­ma (a type of renal cell car­ci­no­ma found in renal tubules), soft tis­sue sar­co­ma (STS), epithe­lial ovar­i­an can­cer and non-small cell lung can­cer (NSCLC).

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our RD com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing linkhttp://​www​.cam​ing​.com/​p​a​z​o​p​a​n​i​b​-​h​y​d​r​o​c​h​l​o​r​i​d​e​-​c​a​s​-​6​3​5​7​0​2​-​6​4​-6/

Quick Inquiry

Fill out our inquiry form and one of our experts will be in touch with you short­ly (Please change screen to hor­i­zon­tal for com­plete brows­ing if you are check­ing Wat­son on your mobile phone).