Identification
CAS Number
98001-69-5
Name
Protamine sulfate
Properties
Appearance
White or off-white powder
Safety Data
WGK Germany
3
Specifications and Other Information of Our Protamine sulfate CAS 98001-69-5
Identification Methods
HNMR, HPLC
Specific Optical Rotation
-65° ~ -85.0°
Nitrogen
21%~25%
Sulfate
16%~24%
Loss on Drying
≤5%
Heavy metal
≤20ppm
Bacterial
≤6EU/mg
Content
Sulfate neutralizes ≥100 Heparin Unitson the dried basis.
Microbial limit
Total aerobic, mould and yeast : ≤100cfu/g
Shelf Life
2 years
Storage
Store below 20℃ and away from light.
Known Application
This product has a strong basic group in its molecule, which can combine with strong acid heparin in the body, causing it to lose its anticoagulant activity. It is a heparin antagonist. Mainly applicable to : ①Bleeding caused by excessive heparin dosage (1mg of protamine Chemicalbook sulfate can neutralize 1mg of heparin). ②Some diseases have hemorrhagic disease with increased heparin-like substances. ③Other causes of bleeding, such as menorrhagia, postpartum hemorrhage, bleeding tendency after radiotherapy, etc.