2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol CAS 121660-11-5

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• Prop­er­ties
• Safe­ty Data
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Iden­ti­fi­ca­tion

CAS Number

121660-11-5

Name

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

Syn­onyms

(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol
[2-Cyclopropyl-4-(4-fluorophényl)-3-quinoléinyl]méthanol [French] [ACD/IUPAC Name]
[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methanol [ACD/IUPAC Name]
[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol
[2-Cyclopropyl-4-(4-fluorphenyl)-3-chinolinyl]methanol [Ger­man] [ACD/IUPAC Name]
121660-11-5 [RN]
3-Quino­­linemethanol, 2-cyclopropyl-4-(4-fluorophenyl)- [ACD/​Index Name]
(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)met
[121660-11-5] [RN]
[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]methan-1-ol
1346600-49-4 [RN]
2-cyclopropan-4-(4-fluorophenyl)-3-quinoline methanol
2-Cyclopropyl-4-(4-Fluorophenyl) -3-quino­­linemethanol
2-Cyclopropyl-4-(4-fluorophenyl) -quinolyl-3-methanol
2-Cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol
2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol-d5
2-Cyclopropyl-4-(4-Fluorophenyl)quinoline-3-Methanol (en)
2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol
2-环丙基-4-(4-氟苯基)-3-喹啉甲醇 [Chi­nese]
DS-12057
Eth­yl 5-amino-1H-pyrrolo[2,3-c]pyridine-2-carboxylate [ACD/IUPAC Name]
MFCD09032924 [MDL num­ber]
Less…

SMILES

Fc4ccc(c1c3ccccc3nc(c1CO)C2CC2)cc4

Std­InChI

InChI=1S/C19H16FNO/c20-14-9-7-12(8-10-14)18-15-3-1-2-4-17(15)21-19(13-5-6-13)16(18)11-22/h1-4,7-10,13,22H,5-6,11H2

Std­InChIKey

FIZD­B­N­PUFMDGFZ-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C₁₉H₁₆FNO

Mol­e­c­u­lar Weight

293.335

MDL Number

MFCD09032924

Prop­er­ties

Appear­ance

White to light yel­low pow­der or crystal

Safe­ty Data

Sym­bol

GHS07

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Puri­ty

99% min

Melt­ing point

132~137°C

Impu­ri­ty I(Destluoro)

≤4.1%

Indi­vid­ual impurity

≤0.1%

Total impu­ri­ties

≤1.0%

Loss on drying

≤0.5%

Shelf Life

2 years

Known Appli­ca­tion

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol is an inter­me­di­ate in the syn­the­sis of Pitavas­tatin cal­ci­um, a statin med­ica­tion pri­mar­i­ly used to low­er cho­les­terol and pre­vent car­dio­vas­cu­lar dis­eases. As an inter­me­di­ate, it plays sev­er­al cru­cial roles in the drug syn­the­sis process : As an inter­me­di­ate, 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol helps to enhance the syn­the­sis effi­cien­cy of Pitavas­tatin cal­ci­um, mak­ing the pro­duc­tion process more effi­cient and controllable.

The qual­i­ty and puri­ty of the inter­me­di­ate direct­ly affect the final drug’s qual­i­ty. High-qual­i­­ty inter­me­di­ates con­tribute to pro­duc­ing Pitavas­tatin cal­ci­um with high­er puri­ty and few­er side effects.

Choos­ing the appro­pri­ate inter­me­di­ate in the drug syn­the­sis process can min­i­mize unnec­es­sary by-prod­ucts, there­by reduc­ing the final drug’s side effects.

The struc­ture of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol con­tributes to the phar­ma­co­log­i­cal activ­i­ty of Pitavas­tatin cal­ci­um, mak­ing it more effec­tive in low­er­ing cho­les­terol and pre­vent­ing car­dio­vas­cu­lar diseases.

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Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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