2-METHY­LAMINO-5-CHLORO BEN­ZOPHE­NONE CAS 1022-13-5

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
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Iden­ti­fi­ca­tion

CAS Number

1022-13-5

Name

2-METHY­LAMINO-5-CHLORO BEN­ZOPHE­NONE CAS 1022-13-5

Syn­onyms

2-METHY­LAMINO-5-CHLORO BENZOPHENONE5-Chlor-2-(methylamino)phenylmethanon [Ger­man] [ACD/IUPAC Name]
5-Chloro-2-(methylamino)phenylmethanone [ACD/IUPAC Name]
5-Chloro-2-(méthylamino)phénylméthanone [French] [ACD/IUPAC Name]
1022-13-5 [RN]
2-(Methylamino)-5-Chlorobenzophenone
213-822-1 [EINECS]
2-Methy­lamino-5-chloroben­­zophe­none
5-Chloro-2-(methylamino)benzophenone
5-chloro-2-methy­laminoben­­zophe­none
Ben­zophe­none, 2-methy­lamino-5-chloro-
Diazepam Relat­ed Com­pound A
Methanone, [5-chloro-2-(methylamino)phenyl]phenyl- [ACD/​Index Name]
Temazepam Relat­ed Com­pound A
(5-Chloro-2-(methylamino)phenyl)(phenyl)methanone
(5-Chloro-2-(methylamino)phenyl)phenylmethanone
(5-chloro-2-methylaminophenyl)-phenylmethanone
(5-chloro-2-methylamino-phenyl)-phenyl-methanone
[5-chloranyl-2-(methylamino)phenyl]-phenyl-methanone
[5-chloro-2-(methylamino)phenyl]-phenylmethanone
[5-chloro-2-(methylamino)phenyl]-phenyl-methanone
[5-Chloro-2-(methylamino)phenyl]phenylmethanone
2-ben­­zoyl-4-chloro-N-methyl­ani­­line
2-METHYL AMINO-5-CHLORO BEN­ZOPHE­NONE
2-Methy­lamino-5-chlor­ben­­zophe­non
2-Methy­lamino-5-chlor­ben­­zophe­none
2-Methyl-oxa­­zole-4-car­boxylic acid
4320-30-3 [RN]
5-Chloro-1-methylim­i­­da­­zole
5-Chloro-2- ben­zophe­none
5-chloro-2-(methylamino)phenyl phenyl ketone
872-49-1 [RN]
98%
Ben­zophe­none, 2-acetami­­do-5-chloro-
Ben­zophe­none, 5-chloro-2-(methylamino)-
ben­zophe­none, 5-chloro-2-methy­lamino-
Methanone, (5-chloro-2-(methylamino)phenyl)phenyl-

SMILES

CNc1ccc(cc1C(=O)c2ccccc2)Cl

Std­InChI

InChI=1S/C14H12ClNO/c1-16-13-8-7-11(15)9-12(13)14(17)10-5-3-2-4-6-10/h2-9,16H,1H3

Std­InChIKey

WPN­M­L­CMT­D­­CANOZ-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C₁₄H₁₂ClNO

Mol­e­c­u­lar Weight

245.704

EINECS

213-822-1

MDL Number

MFCD00008284

Prop­er­ties

Appear­ance

Yel­low crys­talline powder

Safe­ty Data

Sym­bol

GHS07

Sig­nal Word

Warn­ing

Haz­ard statements

Pre­cau­tion­ary Statements

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 2-METHY­LAMINO-5-CHLORO BEN­ZOPHE­NONE CAS 1022-13-5

Iden­ti­fi­ca­tion Methods

Puri­ty

99% min

2-Amino-5-chloroben­­zophe­none

≤1.0%

Melt­ing point

94.0-98.0℃

Loss on Drying

≤0.5%

Residue on Ignition

≤0.2%

Oth­er Impurities

≤0.2%

Total Impu­ri­ties

≤1%

Shelf Life

2 years

Stor­age

Known Appli­ca­tion

2-Methy­lamino-5-chloroben­­zophe­none is an essen­tial inter­me­di­ate pri­mar­i­ly used in syn­the­siz­ing diazepam and medazepam. These med­ica­tions are wide­ly used for their anx­i­olyt­ic, seda­tive, and anti­con­vul­sant prop­er­ties. The struc­tur­al char­ac­ter­is­tics of 2-Methy­lamino-5-chloroben­­zophe­none make it a valu­able pre­cur­sor for syn­the­siz­ing var­i­ous phar­ma­co­log­i­cal­ly active com­pounds, espe­cial­ly in the ben­zo­di­azepine drug class.

In diazepam syn­the­sis, 2-Methy­lamino-5-chloroben­­zophe­none plays a cru­cial role by pro­vid­ing the nec­es­sary amino and chloroaro­mat­ic groups required for the cycliza­tion process, form­ing the core struc­ture of the med­ica­tion. Medazepam, anoth­er ben­zo­di­azepine deriv­a­tive, has sim­i­lar seda­tive effects and is struc­tural­ly relat­ed to diazepam.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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