2’3′-cGAMP sodi­um salt CAS 1441190-66-4

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
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Iden­ti­fi­ca­tion

CAS Number

1441190-66-4

Name

2’3′-cGAMP sodi­um salt

Syn­onyms

1441190-66-4

[RN]
2-Amino-9-[(1R,6R,8R,9R,10S,15R,17R,18R)-8-(6-amino-9H-purin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxido-2,4,7,11,13,16-hexaoxa-3,12-diphosphatricyclo[13.2.1.0~6,10~]octadec-17-yl]-1,9-dihydro-6H-purin- 6-on

[Ger­man]

[IUPAC name – gen­er­at­ed by ACD/​Name]
2-Amino-9-[(1R,6R,8R,9R,10S,15R,17R,18R)-8-(6-amino-9H-purin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxido-2,4,7,11,13,16-hexaoxa-3,12-diphosphatricyclo[13.2.1.0~6,10~]octadec-17-yl]-1,9-dihydro-6H-purin- 6-one

[IUPAC name – gen­er­at­ed by ACD/​Name]
2-Amino-9-[(1R,6R,8R,9R,10S,15R,17R,18R)-8-(6-amino-9H-purin-9-yl)-3,9,12,18-tétrahydroxy-3,12-dioxydo-2,4,7,11,13,16-hexaoxa-3,12-diphosphatricyclo[13.2.1.0~6,10~]octadéc-17-yl]-1,9-dihydro-6H-purin- 6-one

[French]

[IUPAC name – gen­er­at­ed by ACD/​Name]
2′,5′-3′,5′-cGAMP

2′-O,5′-O-((ADENO­SINE-3′-O,5′-O-DIYL)BIS­PHO­S­PHINI­CO)GUANO­SINE

6H-Purin-6-one, 2-amino-9-[(5R,7R,8R,12aR,14R,15R,15aS,16R)-14-(6-amino-9H-purin-9-yl)octahydro-2,10,15,16-tetrahydroxy-2,10-dioxido-5,8-methano-12H-furo[3,2-l]-1,3,6,9,11,2,10-pentaoxadiphosphacyclot etradecin-7-yl]-1,9-dihydro-

[IUPAC index name – gen­er­at­ed by ACD/​Name]
cGAMP(2′-5′)

cyclic [G(2′,5′)pA(3′,5′)p]

SMILES

Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)O[C@H]4C@@HC@HO[C@@H]4COP(=O)(O)O[C@@H]2[C@@H]3O)c(=O)[nH]1

Std­InChI

InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(32)12-7(41-18)2-39-45(36,37)43-13-10(31)6(1-38-44(34,35)42-12)40-19(13)30-5-26-9-16(30)27-20(22)28-17(9)33/h3-7,10-13,18-19,31-32H,1-2H2,(H,34,35)(H,36,37)(H2,21,23,24)(H3,22,27,28,33)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Std­InChIKey

XRIL­CFTWU­CUKJR-INF­S­MZHSSA-N

Mol­e­c­u­lar Formula

C20H24N10O13P2

Mol­e­c­u­lar Weight

674.417

Prop­er­ties

Appear­ance

White pow­der

Safe­ty Data

Sym­bol

Sig­nal Word

Warn­ing

RIDADR 

NONH for all modes of transport

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 2’3′-cGAMP sodi­um salt CAS 1441190-66-4

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

95% min

Water

≤3%

Stor­age

Stor­age at -20 °.

Known Appli­ca­tion

1. Innate immu­ni­ty research : Serves as a potent STING (Stim­u­lat r of Inter­fer­on Genes) path­way ago­nist, wide­ly used to study innate immune respons­es in humans and ani­mals. 2. Can­cer research : Acti­vates the immune sys­tem, sup­port­ing stu­ies on tumor immunother­a­py. 3. Vac­cine adju­vant : Inves­ti­gat­ed for its poten­tial to enhance vac­cine effi­ca­cy. 4. Antivi­ral stud­ies : Used in explor­ing mech­a­nisms against DNA virus­es and some RNA virus­es. 5. Drug devel­op­ment : Employed as a can­di­date mol­e­cule or tool com­pound for devel­op­ing nov­el immunomod­u­la­to­ry therapies.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Warshel Chem­i­cal Ltd (https://​www​.warshel​.com/).

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