compound no - Adenosine Deaminase CAS 9026-93-1

Iden­ti­fi­ca­tion

CAS Number

9026-93-1

Name

Adeno­sine Deaminase

Syn­onyms

Deaminase,adenosine ;
EC 3.5.4.4 ;
HUMAN ADENO­SINE DEAM­I­NASE ;
ADENO­SINE DEAM­I­NASE ;
ADENO­SINE DEAM­I­NASE, BOVINE INTES­TINE ;
ADENO­SINE DEAM­I­NASE TYPE IX ;
ADENO­SINE DEAM­I­NASE TYPE V ;
ADENO­SINE DEAM­I­NASE TYPE VIII

Mol­e­c­u­lar Formula

C20H12Cl2N2O6

Mol­e­c­u­lar Weight

447.225 

EINECS

232-817-5

MDL Number

MFCD00081287

Safe­ty Data

RIDADR 

NONH for all modes of transport 

WGK Germany

2

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our
Adeno­sine Deam­i­nase CAS 9026-93-1

Gen­er­al Assay Characteristics 

Method
Enzymatic/​RATE A/E
ReagentsReady to use
Cal­i­bra­torsLev­el 1-0U/L ; Lev­el 2-50U/L
Cal­i­bra­tion Stability28 days
Sam­ple TypeEDTA,SST,Serum,Heparinised plas­ma
Assay Range3-200U/L undi­lut­ed
Stan­dard­i­s­a­tion

Assay Prin­ci­ple

Assay Principle 2 - Adenosine Deaminase CAS 9026-93-1

Pro­posed ADA Recipe 

Reagent I

Com­po­si­tionCon­cen­tra­tionCat­a­log Number
Tris-HCl buffer50mM
Xan­thine Oxidase1KU/L EM022
4-Aminoan­tipyrine1mM
Purine Nucle­o­side Phosphorylase1KU/L EM021
POD1KU/L
Deter­gent, Preservative

Reagent II

Com­po­si­tionCon­cen­tra­tionCat­a­log Number
Tris-HCl buffer50mM
Adeno­sine10mM
TOOS10mM
Deter­gent, Preservative

Major reagent ingre­di­ents made by Assay Spe­cilist Lab are list on right

Stan­dard&Con­trol

Home Made :ADA in buffer

Reac­tion curve chart 

Calibrator 1 3 - Adenosine Deaminase CAS 9026-93-1
Calibrator 2 3 - Adenosine Deaminase CAS 9026-93-1

Known Appli­ca­tion

Com­mon­ly used in bio­chem­i­cal research, food preser­va­tion, clin­i­cal­ly used as a diag­nos­tic enzyme, deter­mi­na­tion of phos­phor­ic acid and cre­a­tine phos­phate. ADA is a nucle­ic acid cata­bol­ic enzyme that specif­i­cal­ly cat­alyzes the irre­versible deam­i­na­tion of ade­nine nucle­o­sides to pro­duce hypox­an­thine nucle­o­sides, which are then pro­duced by nucle­o­side phos­pho­ry­lase to pro­duce hypox­an­thine, which is under the action of hydrazine oxi­dase. The meta­bol­ic end prod­uct uric acid is excret­ed in the kidneys.

This prod­uct is devel­oped by our R&D com­pa­ny Ulcho Bio­chem­i­cal Ltd(http://​www​.ulcho​.com/), and here is the cor­re­spond­ing linkhttp://​www​.ulcho​.com/​a​d​e​n​o​s​i​n​e​-​d​e​a​m​i​n​a​s​e​-​c​a​s​-​9​0​2​6​-​9​3​-1/

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