Cal­ci­um lev­o­foli­nate CAS 80433-71-2

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions andamp ; Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

80433-71-2

Name

Cal­ci­um lev­o­foli­nate

Syn­onyms

(2S)-2-{[4-({[(6S)-2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-ptéridinyl]méthyl}amino)benzoyl]amino}pentanedioate de cal­ci­um [French] [ACD/IUPAC Name] 80433-71-2 [RN] calcii lev­o­foli­nas [Latin] [INN] Cal­ci­um (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate [ACD/IUPAC Name] Cal­ci­um (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate Cal­ci­um 2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate cal­ci­um lev­o­foli­nate [INN] Cal­ci­um N-(p-((((6S)-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamate (1:1) Cal­ci­um-(2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentandioat [Ger­man] [ACD/IUPAC Name] Elvorine [Trade name] Isovorin [Trade name] lévo­foli­nate de cal­ci­um [French] [INN] lev­o­foli­na­to de cal­cio [Span­ish] [INN] LEV­OLEU­COV­ORIN CAL­CI­UM [USAN] L-Glu­­tam­ic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, cal­ci­um salt (1:1) [ACD/​Index Name] N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic Acid Cal­ci­um Salt (1:1) кальция левофолинат [Russ­ian] [INN] ليفوفولينات كالسيوم [Ara­bic] [INN] 左亚叶酸钙 [Chi­nese] [INN] [80433-71-2] cal­ci­um (2S)-2-[[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]phenyl]-oxomethyl]amino]pentanedioate cal­ci­um (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-keto-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]glutarate cal­ci­um (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate cal­ci­um (2S)-2-[[4-[[(6S)-2-amino-5-methanoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]phenyl]carbonylamino]pentanedioate Cal­ci­um (6S)-foli­nate Cal­ci­um foli­nate [INN] [JP15] Cal­ci­um levofolinate;Elvorine;Isovorin ;CL307782 CL307782 D04715 Isovorin (TN) Leu­cov­orin cal­ci­um [USP] Lev­o­foli­nate cal­ci­um Lev­o­foli­nate cal­ci­um (JAN) L-Leu­­cov­­orin Cal­ci­um MFCD08704249 [MDL num­ber] UNII :778XL6VBS8 UNII-778XL6VB­S8 UNII-RPR1R4C0P4

Mol­e­c­u­lar Structure

SMILES

c1cc(ccc1C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])NC[C@H]2CNc3c(c(=O)nc([nH]3)N)N2C=O.[Ca+2]

Std­InChI

InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12-,13-;/m0./s1

Std­InChIKey

KVUAALJS­MIVURS-QNTK­WALQSA-L

Mol­e­c­u­lar Formula

C20H21CaN7O7

Mol­e­c­u­lar Weight

511.50

Prop­er­ties

Appear­ance

White or light yel­low amor­phous or crys­talline pow­der

Safe­ty Data

Sig­nal Word

Warn­ing

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Cal­ci­um lev­o­foli­nate CAS 80433-71-2

Stan­dard

EP6.0

Cal­ci­um

7.54%~8.14%

Cal­ci­um folinate

97%~102%

Impu­ri­ty H

≤0.5%

Any oth­er impurity

≤0.8%

Total impu­ri­ties

≤1.0%

Chlo­rides

≤0.5%

Spe­cif­ic Opti­cal Rotation

-10.0°~ -15.0°

Heavy Met­als

≤50ppm

Water

10%~17%

pH

7.5~8.5

Ethanol

≤30000ppm

Ace­tone

≤5000ppm

Bac­te­ria endotoxins

≤0.5EU/​mg

Pack­age

Accord­ing to cus­tomer require­ments to pack­ag­ing

Shelf life

2 years

Stor­age

Under the room tem­per­a­ture and away from light

Appli­ca­tion

Main­ly used for the treat­ment of gas­tric can­cer and col­orec­tal can­cer.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our RD com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing linkhttp://​www​.cam​ing​.com/​c​a​l​c​i​u​m​-​l​e​v​o​f​o​l​i​n​a​t​e​-​c​a​s​-​8​0​4​3​3​-​7​1​-2/

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