Identification Properties Safety Data Specifications and Other Information Links Identification CAS Number 305-03-3
Name Chloroambucil
Synonyms Chlorambucil [
BAN ] [
INN ] [
USP ] [Wiki] 305-03-3 [
RN ] 4-{4-[Bis(2-chlorethyl)amino]phenyl}butansäure [German] [
ACD /
IUPAC Name] 4-{4-[Bis(2-chloroethyl)amino]phenyl}butanoic acid [
ACD /
IUPAC Name] Acide 4-{4-[bis(2-chloroéthyl)amino]phényl}butanoïque [French] [
ACD /
IUPAC Name] Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- [
ACD /Index Name] chlorambucil [French] [
INN ] chlorambucilum [Latin] [
INN ] Chloroambucil Clorambucilo [Spanish] [
INN ]
LEUKERAN [Trade name] хлорамбуцил [Russian] [
INN ] كلورامبيوسيل [Arabic] [
INN ] 苯丁酸氮芥 [Chinese] [
INN ] Chlocambucil Leukeran Tablets [305-03-3] 101739-67-1 [
RN ] 128717-77-1 [
RN ] 206-162-0 [
EINECS ] 305-03-3, 337376-15-5 [
RN ] 4-(4-[Bis(2-chloroethyl)amino]phenyl)butanoic acid 4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid 4-(Bis(2-Chloroethyl)amino)benzenebutanoic acid 4-(Bis(2-chloroethyl)amino)phenylbutyric acid 4-(Bis(2-chloroethyl)aminophenyl)butyric acid 4-(bis(2-chloroethyl)aminophenyl)butyricacid 4-(p-(Bis(2-chloroethyl)amino)phenyl)butyric acid 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid 4-(p-bis(2-chloroethyl)aminophenyl)butyric acid 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid 4-(p-Bis(β-chloroethyl)aminophenyl)butyric acid 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid ; 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid ; Chloraminophen ; N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid ; Phenylbutyric Acid Nitrogen Mustard ; γ-[p-di(2-chloroethyl)aminophenyl]butyric acid 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid 4-[4-[bis(2-chloroethyl)amino]phenyl]butyric acid 4-[
BIS (
2-CHLOROETHYL )
AMINO ]
BENZENEBUTANOIC ACID 4-[Bis(2-chloroethyl)amino]benzenebutyric acid 4-[Bis(2-chloroethyl)amino]phenylbutyric acid 4-[Bis(2-chloroethyl)aminophenyl]butyric acid 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid 4[p-Bis(β-chloroethyl)aminophenyl]butyric acid 4-[p-Bis(β-chloroethyl)aminophenyl]butyric acid 4-14-00-01715 (Beilstein Handbook Reference) [Beilstein] 6836-19-7 [
RN ] 999011 [Beilstein] Ambochlorin Amboclorin Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)- Benzenebutanoic acid, 4-[bis (2-chloroethyl)amino]- BPBio1_001208 BSPBio_001098 BSPBio_001971 Butanoic acid, 4-(bis(2-chloroethyl)amino) benzene Butanoic acid, 4-(bis(2-chloroethyl)amino)benzene- Butyric acid, 4-(p-(bis(2-chloroethyl)amino)phenyl) Butyric acid, 4-(p-[bis(2-chloroethyl)amino]phenyl)- Butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)- Butyric acid, 4-[p-[bis (2-chloroethyl)amino]phenyl]- Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]- Cb l348
CB1348 CB-1348 Cbl Celkeran Celkeran (Trade name) Celkeran ; Chloraminophène Chloorambucol Chlorambucil (
USP /
INN ) Chlorambucilum [INN-Latin] chloraminophen Chloraminophene Chloraminophène Chlorbutin chlorbutin|Leukeran® Chlorbutine Chlorbutinum Chlorobutin Chlorobutine Clorambucile [
DCIT ] Clorambucilo [INN-Spanish]
D002699 Ecloril
EINECS 206-162-0 Elcoril Elcorin
ETHANAMINE ,2-[[4-(
1-METHYLETHOXY )
PHENYL ]
SULFONYL ]- g-[p-Di(2-chloroethyl)aminophenyl]butyric Acid γ-[p-di(2-chloroethyl)aminophenyl]butyric acid
IDI1_000688 Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna [Czech] Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna [Czech] Leukeran (
TN ) Leukeran® Leukersan Leukoran Linfolizin linfoly sin
LINFOLYSIN Lopac0_000227 Lympholysin
MFCD00021783 [
MDL number]
MFCD09893688 N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid N,N-Di-(2-chloroethyl)-γ-(p-aminophenyl)butyric acid N,N-Di-2-chloroethyl-g-p-aminophenylbutyric Acid N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid N,N-Di-2-chloroethyl-γ-p-aminophenylbutyric acid N,N-Di-2-chloroethyl-γ-para-aminophenyl butyric acid
NCGC00023250-00 NCGC00023250-05 NCGC00023250-06 NCGC00023250-07 NCGC00023250-08 p-(N, N-Di-2-chloroethyl)aminophenyl butyric acid p-(N,N-di-(β-chloroethyl)aminophenyl)butyric acid p-(N,N-Di-2-chlorethylaminophenyl)butyric acid p-(N,N-Di-2-chloroethyl)aminophenyl butyric acid para-(Di(2-chloroethyl)aminophenyl)butyric acid para-N,N-Di(β-chloroethyl)aminophenyl butyric acid Pharmakon1600-01500171 Phenylbuttersaeure-lost Phenylbuttersaeure-lost [German] p-N, N-Di-(β-chloroethyl)aminophenyl butyric acid p-N,N-Di-(β-chloroethyl)aminophenyl butyric acid p-N,N-Di-(β-chloroethyl)aminophenyl butyric acid Prestwick2_001079 Prestwick3_001079
SPECTRUM1500171 Spectrum5_000677
ST5410766 TL8002353 UNII-18D0SL7309 WLN :
QV3R DN2G2G WR-139013 γ-(p-bis(2-chloroethyl)amino)benzenebutanoic acid γ-(p-bis(2-chloroethyl)aminophenyl)butyric acid γ-(p-Bis(2-chloroethyl)aminophenyl)butyric acid γ-(p-bis(2-chloroethyl)aminophenyl)butyric acid. γ-(p-bis(2-chloroethyl)aminophenyl)butyricacid γ-(p-bis(2-chloroethyl)aminophenyl)butyricacid γ-(p-Di(2-chloroethyl)aminophenyl)butyric acid γ-[p-bis(2-chloroethyl)aminophenyl]butyric acid γ-[p-di(2-chloroethyl)aminophenyl]butyric acid γ-[p-di(2-chloroethyl)aminophenyl]butyric acid γ-[p-Di(2-chloroethyl)aminophenyl]butyric acid
Molecular Structure SMILES c1cc(ccc1CCCC(=O)O)N(CCCl)CCCl
StdInChI InChI=
1S /C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
StdInChIKey JCKYGMPEJWAADB-UHFFFAOYSA-N Molecular Formula C14H19Cl2NO2
Molecular Weight 304.212
EINECS 206-162-0
Beilstein Registry Number 999011
MDL Number MFCD00021783 Properties Appearance White or off-white crystalline powder
Melting Point 65-69℃
Safety Data Symbol GHS06 , GHS08 Signal Word Danger
Hazard Statements H301-H315-H319-H335-H350 Precautionary Statements P201-P261-P301 + P310-P305 + P351 + P338-P308 + P313 Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type
N100 (
US ), Gloves, respirator cartridge type
N100 (
US ), type
P1 (
EN143 ) respirator filter, type
P3 (
EN 143) respirator cartridges
RIDADR UN 2811 6.1 /
PGIII WGK Germany 3
RTECS ES7525000 Specifications and Other Information of Our Chloroambucil CAS 305-03-3 Standard USP39 Identification Methods HNMR /
IR Purity ≥99%
Assay 98%-101%
Water 0.5%max
Residual solvents Ethyl acetate ≤5000ppm
Isopropanol ≤5000ppm
Toluene ≤890ppm
N-hexane ≤290ppm
Total Impurities 1.0%max
Package 100g 500g or according to customer requirements
Storage Preserve in tight light-resistant containers, and store at 2-8℃
Application Commonly used in chronic lymphocytic leukemia, the treatment of lymphatic sarcoma, Hodgkin’s disease, ovarian disease
Links This product is developed by our RandD company Caming Pharmaceutical Ltd(
http://www.caming.com/ ), and here is the corresponding link
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andD purpose. It may be toxic or hazardous, and should be handled only by qualified individuals trained in laboratory procedures. The buyer will be responsible to warn and inform any person that may be in contact with the product of the potential risks and hazards, as well as to ensure that purchase, use and disposal of the product comply with local laws and regulations.