DMPU CAS 7226-23-5

Iden­ti­fi­ca­tion

Name

DMPU

CAS Number

7226-23-5

Syn­onyms

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrim­idi­none 1,3-Dimethyl-2-oxohexahydropyrimidine N,N′-Dimethylpropylene urea N,N’-Dimethyl-N,N’-trimethyleneurea 1,3-Dimethyltetrahydro-2(1H)-pyrim­idi­non 1,3-Dimethyltetrahydro-2(1H)-pyrim­idi­none 1,3-Diméthyltétrahydro-2(1H)-pyrim­idi­none 1,3-Dimethyltetrahydropyrimidin-2(1H)-one 2(1H)-Pyrim­idi­none, tetrahydro-1,3-dimethyl- Tetrahydro-1,3-dimethyl-2(1H)-pyrim­idi­none 1,3-dimethyl-1,3-diazaperhydroin-2-one 1,3-dimethyl-1,3-diazinan-2-one 1,3-Dimethyl-2-oxohexahydropyrimidine 1,3-DIMETHYL-3,4,5,6- TETRAHY­­DRO-2-PYRIM­IDI­NONE 1,3-Dimethyl-3,4,5,6-tetrahydro-2 -pyrim­idi­none 1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one 1,3-Dimethyl-tetrahydro-pyrimidin-2-one 2-PYRIM­I­DONE,TETRAHY­DRO,1,3-DIMETHYL N,N’-Dimethyltrimethyleneurea N,N’-ジメチルプロピレン尿素 tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one Tetrahydro-1,3-dimethyl-2(1H)pyrim­i­dine

Mol­e­c­u­lar Structure

Struc­ture Analysis

a. The strong elec­trophilic effect of car­bonyl struc­ture makes DMPU an apro­t­ic polar sol­vent with high boil­ing point, high flash point and low melt­ing point which is easy to use in fil­tra­tion, dis­til­la­tion, sol­vent extrac­tion and so on ; b. Very low tox­i­c­i­ty, neg­li­gi­ble harm to human body and less pol­lu­tion to the environment;Its high sol­u­bil­i­ty can dis­solve organ­ic, inor­gan­ic, resins, poly­mers, etc.. It also has acti­va­tion prop­er­ties with var­i­ous reagents and mis­ci­bil­i­ty with oth­er high-boil­ing sol­vents ; c. The excel­lent sta­bil­i­ty makes it sta­ble even under hot strong alka­line or acidic con­di­tion as well as resis­tance against water, light and oxy­gen.

SMILES

CN1CCCN(C1=O)C

Std­InChI

InChI=1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3

Std­InChIKey

GUVUOGQB­MY­CBQP-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C6H12N2O

Mol­e­c­u­lar Weight

128.17

EINECS Number

230-625-6

Beil­stein Reg­istry Number

110562

MDL Number

MFCD00006550

Prop­er­ties

Appear­ance

Colour­less trans­par­ent liq­uid

Boil­ing Point

246 ºC

Melt­ing Point

-20 ºC

Flash Point

121 ºC

Den­si­ty

1.064 g/​mL at 25 °C(lit.)

Refrac­tive Index

n20/​D 1.4875-1.4895(lit.)

Vis­cos­i­ty

1.944cp/25℃

Safe­ty Data

Sym­bol

GHS05,GHS07,GHS08

Sig­nal Word

Dan­ger

Haz­ard Statements

H302-H318-H361f

Pre­cau­tion­ary Statements

P280-P305+P351+P338

Per­son­al Pro­tec­tive Equipment

Eye­shields, Faceshields, full-face res­pi­ra­tor (US), Gloves, mul­ti-pur­­pose com­bi­na­tion res­pi­ra­tor car­tridge (US), type ABEK (EN14387) res­pi­ra­tor fil­ter

Haz­ard Codes (Europe)

Xn

Risk State­ments (Europe)

22-36-43

Safe­ty State­ments (Europe)

23-26-36/37/39

WGK Germany

2 

RTECS

UW7582500

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our DMPU CAS 7226-23-5

Puri­ty

99.5% min(By GC)

Iden­ti­fi­ca­tion Method

HNMR, GC

Water

0.1% max

PH

6.5-8.0

Colour

20 max

Impu­ri­ty

0.2% max

Known Appli­ca­tion

DMPU is used as a sol­vent to pro­mote the dis­so­lu­tion of reac­tants, accel­er­ate the reac­tion rate, improve the reac­tion yield and replace tox­ic sol­vents, which can be applied to phar­ma­ceu­ti­cal excip­i­ents. Togeth­er with drugs and oth­er excip­i­ents, DMPU can pro­mote drugs’ dis­so­lu­tion and mix­ing, enhance the sta­bil­i­ty and trans­der­mal absorp­tion capac­i­ty and pro­long the action. DMPU in the appli­ca­tion of phar­ma­ceu­ti­cal prepa­ra­tions : the body of the epi­der­mis is a phys­i­o­log­i­cal bar­ri­er, it pre­vents the entry of in vit­ro sub­stances, so the need for exter­nal prepa­ra­tions to pro­mote the absorp­tion of the skin to pro­mote the sol­vent. This sol­vent should meet the fol­low­ing require­ments : active drug groups can quick­ly and reli­ably reach the site of injury : do not stim­u­late the skin, non-tox­ic ; long time to save sta­bil­i­ty. DMPU can dis­solve a vari­ety of drugs, the human body is almost no tox­i­c­i­ty, with the above require­ments, so it can be used as a drug acces­sories. DMPU and oth­er excip­i­ents and phar­ma­ceu­ti­cal ingre­di­ents can pro­mote the dis­so­lu­tion and mix­ing of drugs to enhance the sta­bil­i­ty of the drug and trans­der­mal absorp­tion capac­i­ty, to extend the role of time.

Pro­duc­tiv­i­ty

600MT/​year

Stor­age

Room tem­per­a­ture away from light

Wat­­son-Int Link

http://​wat​son​-int​.com/​D​M​P​U​_​C​A​S​_​7​2​2​6​-​2​3​-​5​.​h​tml