lacto­fer­rin CAS 146897-68-9

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
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Iden­ti­fi­ca­tion

CAS Number

146897-68-9

Name

lacto­fer­rin

Syn­onyms

COLOSTRUM ;
LAC­TOSIDEROPHILIN (BOVINE);
LACTO­FER­RIN, HUMAN ;
LACTO­FER­RIN, HUMAN MILK ;
LACTO­FER­RIN ;
Lacto­ferricin B

SMILES

CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N1)CO)C)CC(C)C)CCC­CN)CCC­CN)CCSC)CCC­NC(=N)N)Cc3c[nH]c4c3cccc4)CCC(=O)N)Cc5c[nH]c6c5cccc6)CCC­NC(=N)N)CCC­NC(=N)N)NC(=O)[C@H](CCC­CN)NC(=O)[C@H](Cc7ccccc7)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC­NC(=N)N)C(=O)N[C@@H](CCC­NC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc8ccccc8)C(=O)O)[C@@H](C)O

Std­InChI

InChI=1S/C141H224N46O29S3/c1-11-77(6)111-133(212)186-112(80(9)189)134(213)183-106(130(209)184-110(76(4)5)132(211)176-97(49-32-61-161-141(155)156)120(199)170-93(45-28-57-157-137(147)148)116(195)166-78(7)113(192)180-103(136(215)216)66-82-36-16-13-17-37-82)74-219-218-73-105(182-123(202)90(42-22-25-54-142)167-114(193)87(145)65-81-34-14-12-15-35-81)129(208)173-95(47-30-59-159-139(151)152)118(197)171-96(48-31-60-160-140(153)154)122(201)178-102(68-84-70-163-89-41-21-19-39-86(84)89)127(206)174-98(51-52-108(146)190)124(203)179-101(67-83-69-162-88-40-20-18-38-85(83)88)126(205)172-94(46-29-58-158-138(149)150)119(198)175-99(53-63-217-10)125(204)169-91(43-23-26-55-143)117(196)168-92(44-24-27-56-144)121(200)177-100(64-75(2)3)115(194)164-71-109(191)165-79(8)135(214)187-62-33-50-107(187)131(210)181-104(72-188)128(207)185-111/h12-21,34-41,69-70,75-80,87,90-107,110-112,162-163,188-189H,11,22-33,42-68,71-74,142-145H2,1-10H3,(H2,146,190)(H,164,194)(H,165,191)(H,166,195)(H,167,193)(H,168,196)(H,169,204)(H,170,199)(H,171,197)(H,172,205)(H,173,208)(H,174,206)(H,175,198)(H,176,211)(H,177,200)(H,178,201)(H,179,203)(H,180,192)(H,181,210)(H,182,202)(H,183,213)(H,184,209)(H,185,207)(H,186,212)(H,215,216)(H4,147,148,157)(H4,149,150,158)(H4,151,152,159)(H4,153,154,160)(H4,155,156,161)/t77-,78-,79-,80+,87-,90-,91?,92-,93-,94?,95-,96?,97-,98-,99-,100-,101-,102-,103-,104?,105-,106?,107-,110-,111-,112-/m0/s1

Std­InChIKey

PHEG­M­CHJJY­­MA­­DA-WDZ­­JE­JQUSA-N

Mol­e­c­u­lar Formula

C₁₄₁H₂₂₄N₄₆O₂₉S₃

Mol­e­c­u­lar Weight

3123.773

Prop­er­ties

Appear­ance

Light Red to Pink fine powder 

Sol­u­bil­i­ty (ml/10ml@5%)

<0.1

pH solu­tion 2% 

5.5-6.5

For­eign matter 

ABS(class 1)

Sed­i­ment ADMI/​5g

A

Safe­ty Data

RIDADR 

NONH for all modes of transport 

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our lacto­fer­rin CAS 146897-68-9

Iden­ti­fi­ca­tion Methods

HPLC

Assay

≥95%

Mois­ture

≤1.5%

Ash

≤1.5%

Iron sat­u­ra­tion

10-20%

Iron con­tent

< 350 mg/​kg

Melamine

≤0.50ppm

Min­er­al

Cal­ci­um

0.0083 mg/​100g

Chlo­ride

1000 mg/​100g

Phos­pho­rous

0.0053 mg/​100g

Potas­si­um

1.2 mg/​100g

Sodi­um

210 mg/​100g

Lead

≤0.03ppm

Heavy met­als (as lead)

≤5ppm

Arsenic (as)

≤0.01ppm

Nitrate

≤100ppm

Nitrite

≤2ppm

Micro­bi­o­log­i­cal

Aer­o­bic plate count/​g

≤50

Bacil­lus cereus/​g

≤50

Coliforms/​g

absent

E. Coli/​g

absent

Enter­obac­ter sakazakii/​100g (ESAK020405)

absent

Clostrid­i­um perfringens/​g

absent

Shigella/​g

absent

Sul­phite reduc­ing clostridia spores/​g

≤25

Enterobacteriacea/​g

absent

Yeast and moulds/​g

＜1

Coagulase+ve staph aureus 

absent

Inhibito­ry sub­stance μg/​ml

＜0.003

Salmonella/​25g

absent

Listeria/​25g

absent

Resid­ual Pesticides 

absent

Shelf Life

24 months from pro­duc­tion date, in orig­i­nal unopened pack­ing under rec­om­mend­ed stor­age conditions. 

Stor­age

Store in cool and dry place free from tox­ic chem­i­cals and odours. Stor­age tem­per­a­ture : Ambient 

Stor­age humidity

<85%

Pack­ag­ing

0,5-1, 5 and 10 kg PE. Safe for use in con­tact with food­stuffs (EU Reg. 1935/2004 on Gen­er­al Require­ments for all food con­tact mate­ri­als and Reg­u­la­tion 10/2011 on plas­tic mate­ri­als and arti­cles intend­ed to come into con­tact with food). 

Known Appli­ca­tion

lacto­fer­rin is an excel­lent inhibitor of a wide range microor­gan­isms that require iron for growth. As well as being nec­es­sary for nor­mal growth of intesti­nal cells, lacto­fer­rine func­tions as an antiox­i­dant in iron medi­at­ed oxi­da­tion reac­tions and as an anti-inflam­­ma­­to­ry agent. It also may play an impor­tant role in the trans­port of iron across the duo­de­nal mucosa.

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