Iden­ti­fi­ca­tion

CAS Number

9003-97-8

Name

Poly­car­bophil

Syn­onyms

14UH1JQP6L

[UNII]
2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

[ACD/IUPAC Name]
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl 2-[(4-chlorophenyl)oxy]-2-methylpropanoate

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl-2-(4-chlorphenoxy)-2-methylpropanoat

[Ger­man]

[ACD/IUPAC Name]
2-(4-Chlorophénoxy)-2-méthylpropanoate de 2-(1,3-diméthyl-2,6-dioxo-1,2,3,6-tétrahydro-7H-purin-7-yl)éthyle

[French]

[ACD/IUPAC Name]
2-(4-Chlorophenoxy)-2-methylpropanoic Acid 2-(1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl Ester

2-(p-Chlorophenoxy)-2-methylpropionic acid 2-(7-theophyllinyl)ethyl ester

2-(p-Chlorophenoxy)-2-methylpropionic Acid Ester with 7-(2-Hydroxyethyl)theophylline

259-191-6

[EINECS]
54504-70-0

[RN]
clofi­brate d’étofylline

[French]

[INN]
clofi­bra­to de etofilina

[Span­ish]

[INN]
eto­fyllinclofi­brate

eto­fylline clofibrate

[INN]
eto­fylli­ni clofibras

[Latin]

[INN]
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester

[ACD/​Index Name]
Pro­pi­onic acid, 2-(p-chlorophenoxy)-2-methyl-, 2-(7-theophyllinyl)ethyl ester

The­ofi­brate

[USAN]
كلوفيبرات إيتوفيلين

[Ara­bic]

[INN]
益多酯

[Chi­nese]

[INN]

SMILES

Cn1c(=O)c2c(ncn2CCOC(=O)C(C)(C)Oc2ccc(Cl)cc2)n(C)c1=O

Std­InChI

InChI=1S/C19H21ClN4O5/c1-19(2,29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)22(15)3/h5-8,11H,9-10H2,1-4H3

Std­InChIKey

KYAKGJDIS­S­N­VPZ-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C19H21ClN4O5

Mol­e­c­u­lar Weight

420.850

Prop­er­ties

Appear­ance

White loose pow­der, Char­ac­ter­is­tic slight odor

Safe­ty Data

Sig­nal Word

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Poly­car­bophil CAS 9003-97-8

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Absorb­ing Powder

≥62g/​g

Heavy Met­al

≤20ppm

Vis­cos­i­ty

2000~12000mPa·S

Loss on Drying

≤1.5%

Residue on Ignition

≤4%

Acrylic Acid

≤0.3%

Resid­ual Solvents

≤0.45% (Eth­yl acetate)

Shelf Life

2 years

Stor­age

Store at room tem­per­a­ture for long time ; Sealed and keep dry.

Pro­duc­tiv­i­ty

Known Appli­ca­tion

Poly­car­bophil is a high mol­e­c­u­lar weight, crosslinked poly­acrylic acid wide­ly used as a bioad­he­sive poly­mer in phar­ma­ceu­ti­cals and per­son­al care prod­ucts. It serves as a con­trolled-release agent in oral med­ica­tions, a mucoad­he­sive excip­i­ent in vagi­nal and nasal for­mu­la­tions, and a thick­en­ing or mois­tur­iz­ing agent in skin­care and eye care prod­ucts. Its strong water absorp­tion, pro­longed mucos­al adhe­sion, and excel­lent bio­com­pat­i­bil­i­ty make it ide­al for enhanc­ing drug reten­tion and improv­ing user comfort.

Gen­er­al View of Documents

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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