Recombinant Exendin-4 (rExendin-4) CAS 651-01-1816 Watson International Limited

Official Full Name

Recombinant Exendin-4 (rExendin-4)

CAS Number (Or Watson Number for Non-CAS Products)

651-01-1816

Synonyms

Exenatide

Squence

region 651 01 3 - Recombinant Exendin-4 (rExendin-4) CAS 651-01-1816

Amino Acid Sequence

HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS

Synonyms

Exenatide

Accession

P26349

Gene ID

Summary

Source

Escherichia coli.

Molecular Weight

Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.

Biological Activity

1. Regulates Glucose levels rapidly;2. Reduces Insulin resistance;3. Reduces Glucagon;4. Reduces HbA1c;5. Stimulates beta cell growth which stimulates insulin production.

Appearance

Sterile filtered white lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4.

Endotoxin

Less than 10 EU/mg of rExendin-4 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.