Recom­bi­nant Murine LPS-induced CXC Chemokine/​CXCL5 (rMuLIX/​CXCL5) CAS 221-05-1816

Offi­cial Full Name

Recom­bi­nant Murine LPS-induced CXC Chemokine/​CXCL5 (rMuLIX/​CXCL5)

CAS Num­ber (Or Wat­son Num­ber for Non-CAS Products)

221-05-1816

Syn­onyms

Cytokine LIX, Small-inducible Cytokine B5

Squence

Amino Acid Sequence

APSSVI­AATE LRCV­CLTVTP KINPKLIANL EVIPAG­PQCP TVE­VI­AK­LKN QKEV­CLD­PEA PVIKKI­IQ­KI LGS­D­KKKAKR NALAVER­TAS VQ

Syn­onyms

Cytokine LIX, Small-inducible Cytokine B5

Acces­sion

P50228

Gene ID

20311

Sum­ma­ry

CXCL5 is a small cytokine belong­ing to the CXC chemokine fam­i­ly that is also known as epithe­lial-derived neu­trophil-acti­­vat­ing pep­tide 78 (ENA-78) and the gene for CXCL5 is encod­ed by the CXCL5 gene. It May par­tic­i­pate in the recruit­ment of inflam­ma­to­ry cells by injured or infect­ed tis­sue. CXCL5 is cleaved into the fol­low­ing 2 chains : GCP-2 (1-78) and GCP-2 (9-78) which attract neu­trophils and are involved in neu­trophil acti­va­tion. Recom­bi­nant Mouse CXCL5 (92 a.a.) con­tains 92 amino acids and shares 57 % amino acid sequence iden­ti­ty with human CXCL5.

Source

Escherichia coli.

Mol­e­c­u­lar Weight

Approx­i­mate­ly 9.8 kDa, a sin­gle, non-gly­­co­sy­lat­ed polypep­tide chain con­tain­ing 92 amino acids.

Bio­log­i­cal Activity

Ful­ly bio­log­i­cal­ly active when com­pared to stan­dard. The bio­log­i­cal activ­i­ty deter­mined by a chemo­taxis bioas­say using human periph­er­al blood neu­trophils is in a con­cen­tra­tion of 10-100 ng/​ml.

Appear­ance

Ster­ile fil­tered white lyophilized (freeze-dried) pow­der.

For­mu­la­tion

Lyophilized from a 0.2 um fil­tered con­cen­trat­ed solu­tion in 20 mM PB, pH 7.4, 150 mM NaCl.

Endo­tox­in

Less than 1 EU/​ug of rMuLIX/​CXCL5 as deter­mined by LAL method.

Recon­sti­tu­tion

We rec­om­mend that this vial be briefly cen­trifuged pri­or to open­ing to bring the con­tents to the bot­tom. Recon­sti­tute in ster­ile dis­tilled water or aque­ous buffer con­tain­ing 0.1 % BSA to a con­cen­tra­tion of 0.1-1.0 mg/​mL. Stock solu­tions should be appor­tioned into work­ing aliquots and stored at ≤ -20 °C. Fur­ther dilu­tions should be made in appro­pri­ate buffered solu­tions.

Sta­bil­i­ty and Storage

Use a man­u­al defrost freez­er and avoid repeat­ed freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as sup­plied.- 1 month, 2 to 8 °C under ster­ile con­di­tions after recon­sti­tu­tion.- 3 months, -20 to -70 °C under ster­ile con­di­tions after recon­sti­tu­tion.

Ref­er­ences

Puri­ty

> 97 % by SDS-PAGE and HPLC analy­ses.

SDS-PAGE

Pack Size

5ug/​100ug/​500ug

Safe­ty Data Sheet (SDS) Down­load

Click to download

Tech­ni­cal Data Sheet (TDS) Down­load

Click to download

Links

This prod­uct is brand­ed by ChemWhat and sold through our web­site and here is the cor­re­spond­ing link Recom­bi­nant Murine LPS-induced CXC Chemokine/​CXCL5 (rMuLIX/​CXCL5) on ChemWhat

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