Sodi­um lev­o­foli­nate CAS 1141892-29-6

• Iden­ti­fi­ca­tion
• Prop­er­ties
• Safe­ty Data
• Spec­i­fi­ca­tions & Oth­er Information
• Links
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Iden­ti­fi­ca­tion

CAS Number

1141892-29-6

Name

Sodi­um levofolinate

Syn­onyms

(2S)-2-{[4-({[(6S)-2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-ptéridinyl]méthyl}amino)benzoyl]amino}pentanedioate de dis­odi­um [French] [ACD/IUPAC Name]
1141892-29-6 [RN]
Dina­tri­um-(2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentandioat [Ger­man] [ACD/IUPAC Name]
Dis­odi­um (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate [ACD/IUPAC Name]
Dis­odi­um (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate
LEV­OLEU­COV­ORIN DIS­ODI­UM
L-Glu­­tam­ic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, sodi­um salt (1:2) [ACD/​Index Name]
163254-40-8 [RN]
Dis­odi­um foli­nate
LEU­COV­ORIN SODI­UM
UNII-4MX­U9LJS4Q

SMILES

c1cc(ccc1C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])NC[C@H]2CNc3c(c(=O)nc([nH]3)N)N2C=O.[Na+].[Na+]

Std­InChI

InChI=1S/C20H23N7O7.2Na/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);;/q;2*+1/p-2/t12-,13-;;/m0../s1

Std­InChIKey

FSDM­N­N­PYPVJ­­NAT-NJHZP­MQH­SA-L

Mol­e­c­u­lar Formula

C₂₀H₂₁N₇Na₂O₇

Mol­e­c­u­lar Weight

517.403

Prop­er­ties

Appear­ance

White to yel­low amor­phous or crystalline

Safe­ty Data

RIDADR 

Not dan­ger­ous goods

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Sodi­um lev­o­foli­nate CAS 1141892-29-6

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

97% min

Assay(on anhy­drous basis)

97.0-102.0%

Heavy Met­als

≤50ppm

Water

≤17%

Relat­ed substances

Any oth­er impurity

≤2.0%

Total Impu­ri­ties

≤3.0%

D-lsorner

≤1.0%

Shelf Life

1 year

Stor­age

Under room tem­per­a­ture away from light

Known Appli­ca­tion

It can be used as an anti­dote for folic acid antag­o­nists (such as methotrex­ate, pyrimethamine or trimetho­prim, etc.); it can also be used for the treat­ment of mega­loblas­tic ane­mia caused by folate defi­cien­cy and the treat­ment of advanced colon and rec­tal cancer.

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing link http://​www​.cam​ing​.com/​s​o​d​i​u​m​-​l​e​v​o​f​o​l​i​n​a​t​e​-​c​a​s​-​1​1​4​1​8​9​2​-​2​9​-6/

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