Structure of N1 Methylpseudo UTP CAS 1428903 59 6 - N1-Methylpseudo-UTP CAS 1428903-59-6

Iden­ti­fi­ca­tion

CAS Number

1428903-59-6

Name

N1-Methyl­pseu­­do-UTP

Syn­onyms

1-Methylpseudouridine-5′-Triphosphate ;
N1-Methyl­pseu­­do-UTP ;
2,4(1H,3H)-Pyrim­idine­dione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-;
1-Methyl­pseu­­do-UTP

SMILES

CN1C=C(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

Std­InChI

InChI=1S/C10H17N2O15P3/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)

Std­InChIKey

OLRONOIBERD­KRE-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C10H17N2O15P3

Mol­e­c­u­lar Weight

498.171

Prop­er­ties

Appear­ance

Clear colour­less solution

Safe­ty Data

RIDADR 

NONH for all modes of transport

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our N1-Methyl­pseu­­do-UTP CAS 1428903-59-6

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

95%min

Con­cen­tra­tion

100 mM – 110 mM

pH

7.5 ±0.5

Spec­tro­scop­ic Properties

λmax 271 nm, ε 8.9 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Shelf Life

12 months

Stor­age

Stor­age at -20°C, Short term expo­sure (up to 1 week cumu­la­tive) to ambi­ent tem­per­a­ture possible.

Known Appli­ca­tion

N1-MethylpseudoUridine-5′-Triphosphate is a mod­i­fied NTP for incor­po­ra­tion into mes­sen­ger RNAs (mRNA) using T7 RNA Poly­merase. Incor­po­ra­tion of N1-methyl­­pseudouri­­dine can reduce the immuno­genic­i­ty of the result­ing mRNA.

This prod­uct is devel­oped by our R&D com­pa­ny Wat­son Bio Ltd (https://​www​.wat​son​-bio​.com/).

Quick Inquiry

Fill out our inquiry form and one of our experts will be in touch with you shortly.

























    Please prove you are human by select­ing the flag.