Structure of SPDP CAS 68181 17 9 600x348 - SPDP CAS 68181-17-9

Iden­ti­fi­ca­tion

CAS Number

68181-17-9

Name

SPDP

Syn­onyms

1-(1-Oxo-3-(2-pyridyldithio)propoxy)pyrrolidine-2,5-dione
1-{[3-(2-Pyridinyldisulfanyl)propanoyl]oxy}-2,5-pyrrolidindion [Ger­man] [ACD/IUPAC Name]
1-{[3-(2-Pyridinyldisulfanyl)propanoyl]oxy}-2,5-pyrrolidinedione [ACD/IUPAC Name]
1-{[3-(2-Pyridinyldisulfanyl)propanoyl]oxy}-2,5-pyrrolidinedione [French] [ACD/IUPAC Name]
1-{[3-(Pyridin-2-yldisulfanyl)propanoyl]oxy}pyrrolidine-2,5-dione
2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate
2,5-Pyrrolidinedione, 1-(1-oxo-3-(2-pyridinyldithio)propoxy)-
2,5-Pyrrolidinedione, 1-[1-oxo-3-(2-pyridinyldithio)propoxy]- [ACD/​Index Name]
269-034-3 [EINECS]
68181-17-9 [RN]
MFCD00009636 [MDL num­ber]
N-suc­cin­imidyl 3-(2-pyridyldithio)-propionate
N-Suc­cin­imidyl 3-(2-pyridyldithio)propionate
SPDP
(2,5-dioxopyrrolidin-1-yl) 3-(pyridin-2-yldisulfanyl)propanoate
(2,5-dioxopyrrolidin-1-yl)3-(pyridin-2-yldisulfanyl)propanoate
(spdp);n-succinimidyl 3-[2-pyridyldithio]propionate
[68181-17-9] [RN]
1-[1-oxo-3-(2-pyridyldithio)propoxy]pyrrolidine-2,5-dione
1334221-34-9 [RN]
2,5-dioxopyrrolidin-1-yl 3-(pyridin-2- yldisulfanyl)propanoate
3-(2-Pyridyldithio)propionic acid N-hydrox­­y­­suc­cin­imide ester
3-(2-Pyridyldithio)propionic acid N-hydrox­­yuc­cin­imide ester
3-(2-Pyridyldithio)propionic Acid N-Suc­cin­imidyl Ester
3-(2-Pyridyldithio)-propionic acid-OSu
Non­sym­met­ri­cal disul­fide ana­log
N-SUC­CIN­IMIDYL 3,2-(-PYRIDYLDITHIO)PRO­PI­ONATE
n-suc­cin­imidyl 3-[2-pyridyldithio]propionate
n-succinimidyl3-(2-pyridyldithio)propionate
spdp crosslink­er
SPDP NHS ester
SPDP N-Suc­cin­imidyl 3-(2-pyridyldithio)propionate
SPDP ; N-Suc­cin­imidyl 3-(2-pyridyldithio)propionate
SPDP-acid-NHS-ester
SS-0324

SMILES

c1ccnc(c1)SSC­CC(=O)ON2C(=O)CCC2=O

Std­InChI

InChI=1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2

Std­InChIKey

JWD­FQMWE­FLOOED-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C12H12N2O4S2

Mol­e­c­u­lar Weight

312.365

EINECS

269-034-3

Beil­stein Reg­istry Number

1548137

MDL Number

MFCD00009636

Prop­er­ties

Appear­ance

Off-white crys­talline powder

Safe­ty Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our SPDP CAS 68181-17-9

Iden­ti­fi­ca­tion Methods

HNMR, HPLC

Puri­ty

95% min

Con­duc­tiv­i­ty

≤20us/​cm

Sol­u­bil­i­ty

Sol­u­ble in DMFDCM

Shelf Life

2 years

Stor­age

Store at 2-8°C for long time, sealed and away from light.

Known Appli­ca­tion

SPDP (SPDP Crosslink­er) is a cleav­able ADC link­er that can be used to syn­the­size anti­­body-drug con­ju­gates (ADCs) as a gen­er­al-pur­­pose het­ero­func­tion­al crosslink­er for pro­teins and enzymes.

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd (https://​www​.cam​ing​.com/).

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