Tetra­bro­mophe­nol Blue CAS 4430-25-5

Iden­ti­fi­ca­tion

CAS Number

4430-25-5

Name

Tetra­bro­mophe­nol Blue

Syn­onyms

4,4′-(4,5,6,7-tetrabrom-1,1-dioxido-3h-2,1-benzoxathiol-3,3-diyl)bis(2,6-dibrombenzolol)
4,4′-(4,5,6,7-Tetrabrom-1,1-dioxido-3H-2,1-benzoxathiol-3,3-diyl)bis(2,6-dibromphenol)
4,4′-(4,5,6,7-Tetrabromo-1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromophenol)
4,4′-(4,5,6,7-Tétrabromo-1,1-dioxydo-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromophénol)
Phe­nol, 4,4′-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-
4,4′-(4,5,6,7-tetrabromo-3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromophenol) s,s-dioxide
3,3′,3”,4,5,5′,5”,6-Octabromophenolsulfonphthalein
3′,3”,5′,5”-Tetrabromophenol-4,5,6,7-tetrabromosulfonephthalein
3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4,5,6,7-tetrabromobenzo[c]1,2-oxathiolene -1,1-dione
3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4,5,6,7-tetrabromobenzo[c]1,2-oxathiolene-1,1-dione
3,4,5,6,3′,5′,3”,5”-Octabromophenolsulfonphthalein
4,4′-(4,5,6,7-Tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromophenol) S,S-dioxide
4,4′-(4,5,6,7-tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromophenol] S,S-dioxide
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-2,1λ6-benzoxathiole-1,1(3H)-dione
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxy-phenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
Ben­zene­sul­fon­ic acid, 2-(bis(3,5-dibromo-4-hydroxyphenyl)hydroxymethyl)-3,4,5,6-tetrabromo- (9CI)
Tetra­bro­mophe­nol blue
Tetra­bro­mophenyl blue
Tetra­bromphe­nol tetrabromsulfonphthalein

Mol­e­c­u­lar Structure

SMILES

C1=C(C=C(C(=C1Br)O)Br)C2(C3=C(C(=C(C(=C3Br)Br)Br)Br)S(=O)(=O)O2)C4=CC(=C(C(=C4)Br)O)Br

Std­InChI

InChI=1S/C19H6Br8O5S/c20-7-1-5(2-8(21)16(7)28)19(6-3-9(22)17(29)10(23)4-6)11-12(24)13(25)14(26)15(27)18(11)33(30,31)32-19/h1-4,28-29H

Std­InChIKey

QPMIVFWZG­P­T­DPN-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C19H6Br8O5S

Mol­e­c­u­lar Weight

985.54

EINECS

224-622-9

MDL Number

MFCD00005876

Beil­stein Reg­istry Number

378438

Prop­er­ties

Appear­ance

Yel­low or brown powder

Melt­ing Point

203-205 ºC

Safe­ty Data

Per­son­al Pro­tec­tive Equipment

Eye­shields, Gloves, type N95 (US), type P1 (EN143) res­pi­ra­tor filter

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Tetra­bro­mophe­nol Blue CAS 4430-25-5

Iden­ti­fi­ca­tion Methods

HNMR,HPLC

Puri­ty

97% min

Loss on Drying

1.0% max

Water

1.0% max

Ash

1.0% max

Bro­mide

5.0% max

Iodide

0.1% max

Pb

20ppm max

Hg

1ppm max

AS

3ppm max

Fe

100ppm max

Sol­vent Residue

0.1ppm max

Stor­age

Store in a cool(2-8 °C) and dry place, and away from light

Appli­ca­tion

Appli­ca­tions of ana­lyt­i­cal chem­istry and biotech­nol­o­gy
pH Indi­ca­tor
Col­or change range : around pH 3.0 – 4.6
Col­or shift :
Acidic : Yel­low
Alka­line : Blue
Appli­ca­tion : Often used in titra­tions and buffer sys­tems for acidic pH detec­tion.
Pro­tein Detec­tion (Elec­trophore­sis and Stain­ing)
Acts as a track­ing dye dur­ing SDS-PAGE or agarose gel elec­trophore­sis to mon­i­tor the progress of pro­tein migra­tion.
Used as a stain­ing agent for pro­teins on mem­branes (e.g., nitro­cel­lu­lose or PVDF) in col­ori­met­ric detec­tion.
Ana­lyt­i­cal Reagent
Forms com­plex­es with cer­tain com­pounds (e.g., pro­teins or sur­fac­tants), mak­ing it use­ful in quan­ti­ta­tive assays.
Can be used in spec­tropho­to­met­ric meth­ods to mea­sure con­cen­tra­tions of bio­mol­e­cules or ions.
Bio­chem­i­cal and Diag­nos­tic Kits
May be includ­ed in enzyme-linked assays, diag­nos­tic strips, or col­ori­met­ric test kits where pH changes or pro­tein lev­els are indicators.

Appli­ca­tion of hair dye
pH-respon­­sive col­or-chang­ing hair dye (col­or shift effect)
Since it is a pH indi­ca­tor, its col­or changes from yel­low to blue depend­ing on the pH lev­el, mak­ing it suit­able for :
Tem­po­rary hair dyes : form­ing a col­or lay­er on the hair sur­face.
Toy or children’s col­or-chang­ing hair prod­ucts : using low-irri­­ta­­tion acidic or alka­line sys­tems to cre­ate visu­al effects.
​“Col­or-chang­ing hair” prod­ucts : for exam­ple, chang­ing col­or dur­ing wash­ing, or in response to water, heat, or UV light.
Bind­ing to pro­teins to col­or hair
Human hair is pri­mar­i­ly com­posed of ker­atin, a type of pro­tein.
Tetra­bro­mophe­nol Blue is com­mon­ly used in lab­o­ra­to­ry exper­i­ments to detect pro­teins, and under cer­tain con­di­tions, it may bind to hair pro­teins to pro­duce a col­or­ing effect.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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