Tica­grelor CAS 274693-27-5

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions & Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

274693-27-5

Name

Tica­grelor

Syn­onyms

(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol [ACD/IUPAC Name] (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophényl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyéthoxy)-1,2-cyclopentanediol [French] [ACD/IUPAC Name] (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorphenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentandiol [Ger­man] [ACD/IUPAC Name] 1,2-cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- [ACD/​Index Name] 274693-27-5 [RN] 8772 Bril­in­ta [Trade name] Brilique [Trade name] GLH0314RVC Pos­sia [Trade name] Tica­grelor [Wiki] (1S,?2S,?3R,?5S)?-3-?[7-?[[(1R,?2S)?-?2-?(3,?4-?difluorophenyl)?cyclopropyl]?amino]?-?5-?(propyl-?1,?1,?2,?2,?3,?3,?3-?d7-?thio)?-?3H-?1,?2,?3-?triazolo[4,?5-?d]?pyrimidin-?3-?yl]?-?5-?(2-?hydroxyethoxy)?-1,?2-?Cyclopentanediol ? (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3-triazolo[4,5-d]pyrimidinyl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3-triazolo[5,4-d]pyrimidinyl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyl-[1,2,3]triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyl-triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol ;(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol [14C]-Tica­grelor [274693-27-5] 1265911-55-4 [RN] AR-C 126532XX AR-C 126532XX ; AZD 6140 ;AZD6140 ;AZD-6140 AR-C126532XX|AZD6140|Brilinta®|Brilique® Bril­in­ta® Brilique (Trade name) Brilique® Brilique ; Pos­sia com­pound 17 [PMID : 17827008] MFCD09954148 [MDL num­ber] Tica­grelor(AZD6140) TIQ UNII :GLH0314RVC UNII-GLH0314RVC

Mol­e­c­u­lar Structure

SMILES

CCCSc1nc(c2c(n1)n(nn2)[C@@H]3C[C@@H]([C@H]([C@H]3O)O)OCCO)N[C@@H]4C[C@H]4c5ccc(c(c5)F)F

Std­InChI

InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1

Std­InChIKey

OEK­WJQXR­CDYSHL-FNOID­JSQSA-N

Mol­e­c­u­lar Formula

C23H28F2N6O4S

Mol­e­c­u­lar Weight

522.57

Prop­er­ties

Appear­ance

White to pale pink crys­talline pow­der

Safe­ty Data

WGK Germany

3 

MSDS

Tica­grelor CAS 274693-27-5 MSDS

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Tica­grelor CAS 274693-27-5

Stan­dard

Enter­prise stan­dard

Iden­ti­fi­ca­tion Methods

HPLC

Puri­ty

99%min

Spe­cif­ic Opti­cal Rotation

-50°~ -56°

Heavy Met­als

≤10pppm

Chlo­ride

≤0.01%

Loss on Drying

≤0.5%

Residue on Ignition

≤0.1%

Resid­ual Solvents

Eth­yl­ac­etate

≤5000pppm

Petro­le­um ether(calculate by n-hexane)

≤290pppm

Relat­ed Substance

Impu­ri­ty A

≤0.1%

Impu­ri­ty B

≤0.1%

Impu­ri­ty C

≤0.1%

Impu­ri­ty D

≤0.1%

Any Unknow Impurity

≤0.1%

Total Impu­ri­ties

≤1.0%

Pack­age

Accord­ing to cus­tomer require­ments to pack­ag­ing

Stor­age

Under the room tem­per­a­ture and away from light

Appli­ca­tion

It is an anti­co­ag­u­lant ; often used to reduce car­dio­vas­cu­lar death and heart attack in patients with acute coro­nary syn­drome (ACS).

Links

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing linkhttp://​www​.cam​ing​.com/​t​i​c​a​g​r​e​l​o​r​-​c​a​s​-​2​7​4​6​9​3​-​2​7​-5/

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