Identification
CAS Number
458-37-7
Name
Curcumin(Synthesized)
Synonyms
Curcumin (Tautomeric form) [REDIRECT]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-on [German] [ACD/IUPAC Name]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one [ACD/IUPAC Name]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-méthoxyphényl)-1,4,6-heptatrién-3-one [French] [ACD/IUPAC Name]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,4Z,6E)- [ACD/Index Name]
Curcumin [Wiki]
IN00142
(1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one
(1z,4z,6e)-5-Hydroxy-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)hepta-1,4,6-Trien-3-One
115851-80-4 [RN]
458-37-7 [RN]
5-HYDROXY-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTA-1,4,6-TRIEN-3-ONE
CUR
Curcu
Curcumin (Diferuloylmethane)
diferuloylmethane
Diferuloylmethane, Natural Yellow 3, C.I. 75300
Diferuloylmethane;Natural Yellow 3;C.I. 75300
GOLDEN SEAL HYDRASTIS CANADENSIS EXT.
Kacha haldi
Natural yellow 3
Tumeric
SMILES
COc1cc(ccc1O)/C=C/C(=C/C(=O)/C=C/c2ccc(c(c2)OC)O)/O
StdInChI
InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-13,22,24-25H,1-2H3/b7-3+,8-4+,16-13-
StdInChIKey
ZIUSSTSXXLLKKK-KOBPDPAPSA-N
Molecular Formula
C21H20O6
Molecular Weight
368.38
EINECS
207-280-5
Beilstein Registry Number
2306965
MDL Number
MFCD00008365
Properties
Appearance
Brownish-yellow to Orange-yellow Powder
Safety Data
RIDADR
NONH for all modes of transport
WGK Germany
3
RTECS
MI5230000
Specifications and Other Information of Our Curcumin(Synthesized) CAS 458-37-7
Identification Methods
HPLC
Total Crucuminoide (by HPLC)
≥95%
Loss on Drying
≤1.0%
Heavy Metals
≤10ppm
Pb
<2.0ppm
As
<2.0ppm
Hg
<0.1ppm
Cd
<2.0ppm
Total Plate Count
≤10000cfu/g
Yeast & Mold
≤100cfu/g
E.Coli
Non-detective
Salmonella
Non-detective
Shelf Life
2 years
Storage
Store in cool and dry place, away from light.
Known Application
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) ac tivity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase. Inhibits inducible nit ric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nucle ar envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease.