Structure of Gallium Maltolate CAS 108560 70 9 - Gallium Maltolate CAS 108560-70-9

Iden­ti­fi­ca­tion

CAS Number

108560-70-9

Name

Gal­li­um Maltolate

Syn­onyms

108560-70-9 [RN]
4H-Pyran-4-one, 3-hydroxy-2-methyl-, gal­li­um salt (3:1) [ACD/​Index Name]
GAL­LI­UM MAL­TO­LATE
Gal­li­um tris(2-methyl-4-oxo-4H-pyran-3-olate) [ACD/IUPAC Name]
Galliumtris(2-methyl-4-oxo-4H-pyran-3-olat) [Ger­man] [ACD/IUPAC Name]
Tris(2-méthyl-4-oxo-4H-pyran-3-olate) de gal­li­um [French] [ACD/IUPAC Name]
3-Bis[(2-methyl-4-oxopyran-3-yl)oxy]gallanyloxy-2-methylpyran-4-one

SMILES

Cc1c(c(=O)cco1)[O-].Cc1c(c(=O)cco1)[O-].Cc1c(c(=O)cco1)[O-].[Ga+3]

Std­InChI

InChI=1S/3C6H6O3.Ga/​c31-4-6(8)5(7)2-3-9-4;/h32-3,8H,1H3;/q;;;+3/p-3

Std­InChIKey

ASYY­OZS­­DALAN­RF-UHF­F­­FAOYSA-K

Mol­e­c­u­lar Formula

C18H15GaO9

Mol­e­c­u­lar Weight

445.029

Prop­er­ties

Appear­ance

Off-white or light pink powder

Safe­ty Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Gal­li­um Mal­to­late CAS 108560-70-9

Iden­ti­fi­ca­tion Methods

HNMR

Puri­ty

98% min

Ga

15%min

Shelf Life

2 years

Stor­age

Under room tem­per­a­ture away from light

Advan­tage

Gal­li­um mal­to­late, by offer­ing the advan­tages of enhanced bioavail­abil­i­ty, poten­tial­ly improved ther­a­peu­tic prop­er­ties and ease of admin­is­tra­tion, could sig­nif­i­cant­ly expand the ther­a­peu­tic poten­tial of gal­li­um. To inves­ti­gate the use/​treatment of blad­der can­cer, lym­phoma (not spec­i­fied), mul­ti­ple myelo­ma, pag­ing dis­ease and prostate cancer.

Known Appli­ca­tion

Gal­li­um mal­to­late is a nov­el active for­mu­la­tion of gal­li­um, a semi­met­al ele­ment, and a potent inhibitor of ribonu­cleotide reduc­tase, an enzyme that pro­motes tumor growth. Gal­li­um is also thought to con­cen­trate in malig­nan­cies and sites of infec­tion, and appears to favor­ably affect cal­ci­um depo­si­tion, mak­ing bones more resis­tant to degra­da­tion caused by can­cer metastases.

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd (https://​www​.cam​ing​.com/).

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