Structure of Levothyroxine sodium CAS 55 03 825416 65 3 - Levothyroxine sodium CAS 55-03-8(25416-65-3)

Iden­ti­fi­ca­tion

CAS Number

55-03-8(25416-65-3)

Name

Levothy­rox­ine sodium

Syn­onyms

Levothy­rox­ine Sodi­um [INN] [USAN]
(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophénoxy)-3,5-diiodophényl]propanoate de sodi­um [French] [ACD/IUPAC Name]
200-221-4 [EINECS]
216-080-7 [EINECS]
453
55-03-8 [RN]
Eltrox­in [Trade name]
Euthy­rox [Trade name]
L-3,3′,5,5′-Tetraiodothyronine Sodi­um Salt
Lev­ax­in [Trade name]
Levothroid [Trade name]
lévothy­rox­ine sodique [French] [INN]
levothy­rox­inum natricum [Latin] [INN]
lev­otirox­i­na de sodio [Span­ish] [INN]
Lev­otirox­i­na sod­i­ca [Span­ish] [INN]
Lev­oxyl [Trade name]
L-Thy­rox­­ine monosodi­um salt
L-Thy­rox­­ine sodi­um salt [USP]
L-Tyro­­sine, O- (4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodi­um salt
L-Tyro­­sine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodi­um salt (1:1) [ACD/​Index Name]
Natri­um-(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodphenoxy)-3,5-diiodphenyl]propanoat [Ger­man] [ACD/IUPAC Name]
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Monosodi­um Salt
Orox­ine [Trade name]
Sodi­um (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate [ACD/IUPAC Name]
Sodi­um Levothy­rox­ine
Sodi­um l-thy­rox­in
SODI­UM L-THY­ROX­INE
Syn­throid [Trade name]
Thy­ro-Tabs [Trade name]
левотироксин натрия [Russ­ian] [INN]
ليفوثيروكسين صوديوم [Ara­bic] [INN]
左甲状腺素钠 [Chi­nese] [INN]
[55-03-8]
3,3´,5,5´-Tetraiodo-L-thyronine sodi­um salt
3,3′,5,5′-Tetraiodo-L-thyronine, sodi­um salt
3,3?,5,5?-Tetraiodo-L-thyronine sodi­um salt
5721845 [Beil­stein]
Dathroid
DL-THY­ROX­­INE SODI­UM SALT
EINECS 200-221-4
EINECS 216-080-7
Laevox­in
Let­ter
Lev­orox­ine
Levo-T
Levothy­roid
Levothy­rox
levothy­rox­ine sodique
Levothy­rox­ine sodique [INN-French]
Levothy­rox­i­ne­sodi­um
Levothy­rox­in-natri­um
levothy­rox­inum natricum
Levothy­rox­inum natricum [INN-Latin]
lev­otirox­i­na de sodio
Lev­otirox­i­na sod­i­ca [INN-Span­ish]
Lev­ox­ine
L-thy­rox­­ine sodi­um
L-Tyro­­sine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodi­um salt
MFCD00002596
Novothy­rox
Pow­dered Thy­roid
QA-1528
Ro-thy­rox­ine
Rox­s­tan
sodi­um (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate
sodi­um (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propionate
sodi­um (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate
SODI­UM LEVOTHY­ROX­INE(1-)
sodi­um O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosinate
Sodi­um thy­rox­in
Sodi­um thy­rox­i­nate
Sodi­um thy­rox­ine
Sodi­um­levothy­rox­ine
Sodi­um-L-thy­rox­ine
Solox­ine
ST5330577
Syn­throid sodi­um
Tetroid
Thyradin [Wiki]
Thyradin S
Thyrax [Wiki]
Thy­roid [Wiki]
Thy­rol L
Thy­ron­amin
Thy­rox­e­van
Thy­rox­in sodi­um
Thy­rox­ine sodique
thy­rox­ine sodi­um
THY­ROX­INE, MONOSODI­UM SALT, L-
Thy­rox­inum natricum
Tiroid­i­na
tirosint
Unithroid

SMILES

c1c(cc(c(c1I)Oc2cc(c(c(c2)I)O)I)I)C[C@@H](C(=O)[O-])N.[Na+]

Std­InChI

InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m0./s1

Std­InChIKey

YDT­FR­JL­N­MP­SCFMYDAL­LXLXSA-M

Mol­e­c­u­lar Formula

C15H10I4NNaO4

Mol­e­c­u­lar Weight

798.852 

EINECS

200-221-4

MDL Number

MFCD06408007

Prop­er­ties

Appear­ance

Off-white to buff colored powder

Safe­ty Data

Per­son­al Pro­tec­tive Equipment

Eye­shieldsGlovestype N95 (US)type P1 (EN143) res­pi­ra­tor filter

RIDADR 

NONH for all modes of transport 

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Levothy­rox­ine sodi­um CAS 55-03-8(25416-65-3)

Iden­ti­fi­ca­tion Methods

HPLC

Assay

100%~103%

Spe­cif­ic Opti­cal Rotation

-5 ° ~ -6 ° 

Water

≤11%

Relat­ed substances

Lio­thy­ro­nine

≤1.0%

Beta hydroxy-T 4a

≤ 0.15%

T4-Hydroxy Acetic acid 

≤0.15%

N-Formyl-T4 and T4 Acetamide

≤0.15%

N-Acetyl-T 4

≤0.20%

T4-Aceti­­ci acid

≤0.30%

T4-Alde­hyde

≤0.15%

T4-Ben­­zoic Acid

≤0.15%

Indi­vid­ual unspec­i­fied impurity

≤0.10%

Total impu­ri­ties

≤0.20%

Resid­ual solvents

Ethanol

≤5000ppm

1-Propanol

≤5000ppm

2-propanol

≤5000ppm

lso­propyl acetate

≤5000ppm

Acetic acid con­tent (by HPLC

≤5000ppm

Shelf Life

1 year

Stor­age

Store in a closed con­tain­er at room tem­per­a­ture at 25℃~30 ℃.

Pro­duc­tiv­i­ty

1MT/​month

Known Appli­ca­tion

Com­mon­ly used as corticosteroid.

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing linkhttp://​www​.cam​ing​.com/​l​e​v​o​t​h​y​r​o​x​i​n​e​-​s​o​d​i​u​m​-​c​a​s​-​5​5​-​0​3​-​8​(​2​5​4​1​6​-​6​5​-​3)/

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