Ati­pame­zole CAS 104054-27-5

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions andamp ; Oth­er Information Links

Iden­ti­fi­ca­tion

Name

Ati­pame­zole

CAS Number

104054-27-5

Syn­onyms

1H-imi­­da­­zole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)- 1H-imi­­da­­zole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)- 5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole Ati­pame­zole 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole 4-(2-Ethyl-2-indanyl)imidazole 4-(2-Ethyl-indan-2-yl)-1H-imidazole(Atipamezole) 4-(2-ethylindan-2-yl)imidazole Anti­sedan Anti­sedan Ati­pame­zol Ati­pame­zolum

Mol­e­c­u­lar Structure

SMILES

n1cc(nc1)C3(Cc2c(cccc2)C3)CC

Std­InChI

InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)

Std­InChIKey

HSW­PZIDYAHLZDD-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C14H16N2

Mol­e­c­u­lar Weight

212.29

MDL Number

MFCD00864502

Prop­er­ties

Appear­ance

White Sol­id

Sol­u­bil­i­ty

DMSO≥30 mg/​mL

Boil­ing Point

367.131 °C at 760 mmHg

Flash Point

178.006 °C

Den­si­ty

1.116g/mL

Safe­ty Data

Sym­bol

GHS06

Sig­nal Word

Dan­ger

Haz­ard Statements

H301

Pre­cau­tion­ary Statements

P301+P310

Per­son­al Pro­tec­tive Equipment

Eye­shields, Faceshields, Gloves, type P2 (EN 143) res­pi­ra­tor car­tridges

Haz­ard Codes (Europe)

T

Risk State­ments (Europe)

25

Safe­ty State­ments (Europe)

45

RIDADR

UN 2811 6.1/PG 3 

WGK Germany

3 

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Ati­pame­zole CAS 104054-27-5 (Hydrochlo­ride CAS 104075-48-1)

Puri­ty

98%min(By HPLC)

Iden­ti­fi­ca­tion Method

NMR, HPLC

Biochem/​physiol Actions

Ati­pame­zole is more potent than yohim­bine ; it is very selec­tive for alpha2-adren­er­g­ic vs alpha1sites, but not selelctive for alpha2 – sub­types.

Known Appli­ca­tion

Ati­pame­zole is a syn­thet­ic alpha2-adren­er­g­ic antag­o­nist, indi­cat­ed for the rever­sal of the seda­tive and anal­gesic effects of dexmedeto­mi­dine and medeto­mi­dine in dogs. It has also been researched in humans as a poten­tial anti-Park­in­­son­ian drug.

Pro­duc­tiv­i­ty

10Kg/​month

Stor­age

Sealed, away from light, 2-8°C for long time stor­age

Gen­er­al View of Documents

Wat­­son-Int Link

https://​www​.wat​son​-int​.com/​A​t​i​p​a​m​e​z​o​l​e​_​C​A​S​_​1​0​4​0​5​4​-​2​7​-​5​.​h​tml

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