Structure of Mitoquinone mesylate CAS 845959-50-4

Iden­ti­fi­ca­tion

CAS Number

845959-50-4

Name

Mito­quinone mesylate

Syn­onyms

10-(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decylphosphonium methane­sul­fonate [ACD/IUPAC Name]
10-(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decylphosphoniummethansulfonat [Ger­man] [ACD/IUPAC Name]
6E01CG547T
845959-50-4 [RN]
Méthane­sul­fonate de 10-(4,5-diméthoxy-2-méthyl-3,6-dioxo-1,4-cyclohexadién-1-yl)décylphosphonium [French] [ACD/IUPAC Name]
MitoQ [Wiki]
MIto­quinone (mesy­late)
mito­quinone mesy­late
mitoubiquinone mesy­late
Phos­pho­ni­um, [10-(4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl- methane­sul­fonate (1:1) [ACD/​Index Name]
[10-(4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium, monomethane­sul­fonate
10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl-triphenylphosphanium;methanesulfonate
845959-50-4 (mesy­late)
MFCD30747833
Mito­quinone (MitoQ10) mesy­late
UNII :6E01CG547T
UNII-6E01CG547T

SMILES

CC1=C(C(=O)C(=C(C1=O)OC)OC)CCC­C­C­C­C­C­CC[P+](c2ccccc2)(c3ccccc3)c4ccccc4.CS(=O)(=O)[O-]

Std­InChI

InChI=1S/C37H44O4P.CH4O3S/c1-29-33(35(39)37(41-3)36(40-2)34(29)38)27-19-8-6-4-5-7-9-20-28-42(30-21-13-10-14-22-30,31-23-15-11-16-24-31)32-25-17-12-18-26-32;1-5(2,3)4/h10-18,21-26H,4-9,19-20,27-28H2,1-3H3 ;1H3,(H,2,3,4)/q+1;/p-1

Std­InChIKey

GVZ­­FU­VX­PT­P­­GO­QT-UHF­F­­FAOYSA-M

Mol­e­c­u­lar Formula

C38H47O7PS

Mol­e­c­u­lar Weight

678.814

MDL Number

MFCD30747833

Prop­er­ties

Appear­ance

Red­dish brown paste

Safe­ty Data

Sym­bol

exclamation-mark-jpgH302-H315-H319

Sig­nal Word

Warn­ing

Haz­ard statements

H302-H315-H319

Pre­cau­tion­ary Statements

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

WGK Germany

3

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our 

Iden­ti­fi­ca­tion Methods

HPLC

Puri­ty

95% min

Sol­vent Residues

≤5000ppm

Loss on drying

≤5.0%

Heavy Met­als

≤10ppm

Lead

≤2ppm

Arsenic

≤1ppm

Mer­cury

≤0.1ppm

Cad­mi­um

≤1ppm

Total Plate Count

<1000cfu/​g

Yeast& Mold

<100cfu/​g

E.Coli

Neg­a­tive

Sal­mo­nel­la

Neg­a­tive

Staphy­lo­coc­cus

Neg­a­tive

Shelf Life

2 years

Stor­age

store in cool & dry place, keep away from strong light and heat.

Known Appli­ca­tion

Mitox­antrone Methane­sul­fonate is pri­mar­i­ly used for can­cer treat­ment. It is an anti­neo­plas­tic (anti­cancer) agent clas­si­fied as an anthraquinone antibi­ot­ic. The pri­ma­ry ther­a­peu­tic uses include :

Breast Can­cer : Mitox­antrone is often used to treat advanced or metasta­t­ic breast can­cer.
Prostate Can­cer : Par­tic­u­lar­ly effec­tive in treat­ing hor­­mone-refrac­­to­ry prostate can­cer.
Leukemia : It is used to treat cer­tain types of leukemia, such as acute myeloid leukemia (AML).
Lym­phomas and Oth­er Sol­id Tumors : Mitox­antrone may also be used in the treat­ment of cer­tain lym­phomas and oth­er types of sol­id tumors.
Mul­ti­ple Scle­ro­sis (MS): Mitox­antrone is occa­sion­al­ly used to treat relaps­ing or pro­gres­sive forms of mul­ti­ple scle­ro­sis to slow the pro­gres­sion of the dis­ease.
This drug works by inter­fer­ing with DNA syn­the­sis and repli­ca­tion, thus inhibit­ing the growth of can­cer cells.

Gen­er­al View of Documents

HPLC of Mitoquinone mesylate CAS 845959-50-4
HPLC of Mito­quinone mesy­late CAS 845959-50-4

This prod­uct is devel­oped by our R&D com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Lim­it­ed (http://​www​.cam​ing​.com/).

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