Pazopanib hydrochloride CAS 635702-64-6

Identification Properties Safety Data Specifications andamp; Other Information Links

Identification

CAS Number

635702-64-6

Name

Pazopanib hydrochloride

Synonyms

5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide hydrochloride (1:1) [ACD/IUPAC Name] 5-({4-[(2,3-Diméthyl-2H-indazol-6-yl)(méthyl)amino]-2-pyrimidinyl}amino)-2-méthylbenzènesulfonamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name] 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzolsulfonamidhydrochlorid (1:1) [German] [ACD/IUPAC Name] 635702-64-6 [RN] Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1) [ACD/Index Name] GW786034B GW-786034B Pazopanib Hydrochloride [USAN] Votrient [Trade name] [635702-64-6] 444731-52-6 [RN] 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide hydrochloride 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide hydrochloride 5-[[4-[(2, 3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2- methylbenzenesulfonamide;hydrochloride 5-[[4-[(2,3-dimethyl-6-indazolyl)-methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide hydrochloride 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide and hydron and chloride 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride 5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide HCl 5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide hydrochloride Armala GW 786034 GW786034 GW786034;Votrient;Armala;GW 786034;GW-786034 GW786034GW786034, VOTRIENT HYDROGEN PAZOPANIB CHLORIDE MFCD12546138 [MDL number] Pazopanib Pazopanib (GW-786034) Pazopanib (Hydrochloride) Pazopanib HCL Pazopanib HCl (GW786034 HCl) pazopanib monohydrochloride Pazopanib, Votrient, GW786034B, GW 786034, GW-786034 UNII:33Y9ANM545 UNII-33Y9ANM545

Molecular Structure

Structure of Pazopanib hydrochloride CAS 635702-64-6

SMILES

Cc1ccc(cc1S(=O)(=O)N)Nc2nccc(n2)N(C)c3ccc4c(n(nc4c3)C)C.Cl

StdInChI

InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H

StdInChIKey

MQHIQUBXFFAOMK-UHFFFAOYSA-N

Molecular Formula

C21H23N7O2S.HCl

Molecular Weight

473.98

Properties

Appearance

White to off-white powder

Safety Data

WGK Germany

Specifications and Other Information of Our Pazopanib hydrochloride CAS 635702-64-6

Standard

Enterprise standard

Identification Methods

HPLC,XRD

Purity

99%min

Heavy Metals

10 ppm max

Loss on Drying

0.5% max

Residue on Ignition

0.2% max

Single Impurity

0.2% max

Total Impurities

0.5% max

Package

According to customer requirements to packaging

Manufacturing Capacity

KG Scale

Storage

Under room temperature away from light

Application

Palazepine Hydrochloride is a novel type of oral angiogenesis inhibitor that can interfere with the angiogenesis required for the survival and growth of stubborn tumors, targeting the role of vascular endothelial growth factor receptor (VEGFR), by inhibiting the new blood supply to the tumor Angiogenesis and work. Suitable for the treatment of advanced renal cell carcinoma (a type of renal cell carcinoma found in renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer and non-small cell lung cancer (NSCLC).