R-alpha-Lipoic acid sodi­um CAS 176110-81-9

Iden­ti­fi­ca­tion
Prop­er­ties
Safe­ty Data
Spec­i­fi­ca­tions andamp ; Oth­er Information
Links

Iden­ti­fi­ca­tion

CAS Number

176110-81-9

Name

R-alpha-Lipoic acid sodium

Syn­onyms

1,2-Dithiolane-3-pentanoic acid, sodi­um salt, (3R)- (1:1) [ACD/​Index Name]
5-[(3R)-1,2-Dithiolan-3-yl]pentanoate de sodi­um [French] [ACD/IUPAC Name]
Natri­um-5-[(3R)-1,2-dithiolan-3-yl]pentanoat [Ger­man] [ACD/IUPAC Name]
Sodi­um 5-[(3R)-1,2-dithiolan-3-yl]pentanoate [ACD/IUPAC Name]
176110-81-9 [RN]
2319-84-8 [RN]
Sodi­um (R)-5-(1,2-dithiolan-3-yl)pentanoate
Sodi­um thioc­tate
UNII-L9R2W­B­J3BR

Mol­e­c­u­lar Structure

Struc­ture of R-alpha-Lipoic acid sodi­um CAS 176110-81-9

SMILES

C1CSS[C@@H]1CCCCC(=O)[O-].[Na+]

Std­InChI

InChI=1S/C8H14O2S2.Na/c9-8(10)4-2-1-3-7-5-6-11-12-7;/h7H,1-6H2,(H,9,10);/q;+1/p-1/t7-;/m1./s1

Std­InChIKey

UUD­F­BR­WL­HZ­I­IQX-OGFXRTJISA-M

Mol­e­c­u­lar Formula

C8H13NaO2S2

Mol­e­c­u­lar Weight

228.307

Prop­er­ties

Appear­ance

Off white or pale yel­low powder

Melt­ing Point

240℃~250℃

Safe­ty Data

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our R-alpha-Lipoic acid sodi­um CAS 176110-81-9 

Stan­dard

Enter­prise standard

Iden­ti­fi­ca­tion Methods

HNMR,HPLC

Assay by HPLC

99%min

Assay of R-alpha-Lipoic acid by HPLC

80%min

Spe­cif­ic Opti­cal Rotation

+60°~+85°

Heavy Met­als

10ppm max

Loss on Drying

3.0%max

Pack­age

Accord­ing to cus­tomer require­ments to packaging

Stor­age

Under the room tem­per­a­ture and away from light

Appli­ca­tion

Lipoic acid (LA), also known as alpha lipoic acid (ALA) and thioc­tic acid is an organosul­fur com­pound which is wide­ly used as a dietary sup­ple­ment in some coun­tries mar­ket­ed as an antiox­i­dant and is avail­able as a phar­ma­ceu­ti­cal drug in oth­er countries.

Alpha-Lipoic Acid bulk mate­r­i­al avail­able today is (R/S) or (+/-) Alpha Lipoic Acid (ALA), mean­ing it con­tains a 50/50 mix­ture of (R-Lipoic) and unnat­ur­al (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found any­where in nature, is a byprod­uct of chem­i­cal syn­the­sis. Research indi­cates that not only does the human body have dif­fi­cul­ty absorb­ing this unnat­ur­al ver­sion, it may inhib­it the most essen­tial prop­er­ties of the R-Lipoic Acid form !

The ​“R” form (R Lipoic) is con­sid­ered the ​“eutomer” (the bio­log­i­cal­ly supe­ri­or form) of Alpha Lipoic Acid, since it is iden­ti­cal to that pro­duced by the body. Research indi­cates R-Lipoic Acid is respon­si­ble for most of the ben­e­fi­cial effects attrib­uted to ALA.

While R Lipoic Acid is the obvi­ous choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its ​“free-acid” form has two major draw­backs : sta­bil­i­ty and bioavail­abil­i­ty. With­out spe­cial pro­cess­ing, R-Lipoic Acid is high­ly unsta­ble and dif­fi­cult to absorb. In fact, phar­ma­co­ki­net­ic data reveal that while Alpha Lipoic Acid has a very low absorp­tion rate, unsta­bi­lized R-Lipoic Acid is absorbed even worse !

As one of the largest fine chem­i­cal devel­op­ers glob­al­ly, Wat­son solved the sta­bil­i­ty issue by bring­ing in two oth­er derivates R(+)-Alpha Lipoic Acid Sodi­um CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8, being one of the world’s largest pur­vey­or of com­mer­cial­ly pro­duced sta­bi­lized R-Lipoic Acid materials.

You know check here to know more about our two products,

R-(+)-alpha-Lipoic acid CAS 1200-22-2 : https://​www​.wat​son​-int​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​c​a​s​-​1​2​0​0​-​2​2​-2/

R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8 : https://​www​.wat​son​-int​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​t​r​o​m​e​t​h​a​m​i​n​e​-​s​a​l​t​-​c​a​s​-​1​4​3​5​8​-​9​0​-8/

Links

This prod­uct is devel­oped by our RD com­pa­ny Ulcho Bio­chem­i­cal Ltd(http://​www​.ulcho​.com/), and here is the cor­re­spond­ing linkhttp://​www​.ulcho​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​s​o​d​i​u​m​-​c​a​s​-​1​7​6​1​1​0​-​8​1​-9/

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