R-(+)-alpha-Lipoic acid CAS 1200-22-2

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions andamp ; Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

1200-22-2

Name

R-(+)-alpha-Lipoic acid

Syn­onyms

(±)-1,2-Dithiolane-3-valeric acid 1,2-Dithiolane-3-pentanoic acid [ACD/​Index Name] 200-534-6 [EINECS] 5-(1,2-Dithiolan-3-yl)pentanoic acid [ACD/IUPAC Name] 5-(1,2-Dithiolan-3-yl)pentansäure [Ger­man] [ACD/IUPAC Name] 6,8-Dihydrothioctic acid Acide 5-(1,2-dithiolan-3-yl)pentanoïque [French] [ACD/IUPAC Name] DL-Thioc­tic acid lipoic acid [Wiki] Thioc­tic acid [JAN] UNII :73Y7P0K73Y (+)-α-Lipoic acid (±)-1,2-Dithiolane-3-pentanoic acid (±)-1,2-Dithiolane-3-pentanoic acid (±)-1,2-Dithiolane-3-valeric acid (±)-Lipoic acid (±)-Lipoic acid (±)-Thioc­tic acid (±)-α-Lipoic acid (±)-α-Lipoic acid (R)-(+)-lipoic acid (R)-1,2-Dithiolane-3-pentanoic acid (R)-6,8-thioctic acid (R)-lipoate (R)-lipoic acid (RS)-Lipoic acid (RS)-α-Lipoic acid [1077-27-6] [1077-28-7] 1,2-Dithiolane-3-pentanoic acid, (±)- 1,2-Dithiolane-3-pentanoic acid, (±)- 1,2-dithiolane-3-pentanoic acid ; 1,2-dithiolane-3-valeric acid ; 5-(1,2-dithiolan-3-yl)valeric acid ; 5-(dithiolan-3-yl)valeric acid ; 5-[3-(1,2-dithiolanyl)]pentanoic acid ; 6-thioc­tic acid ; 6-thi­ot­ic acid ; 6,8-thioctic acid ; 6,8-thiotic acid ; Acetate-replac­ing fac­tor ; α-Lipoic acid ; α-Lipons??ure ; Bile­tan ; lipon­ic acid ; Thioctans??ure ; Thioc­tic acid ; Thiocts??ure ; Thiokts??ure ; ??-lipoic acid 1,2-dithiolane-3-pentanoic acid ; 1,2-dithiolane-3-valeric acid ; 5-(1,2-dithiolan-3-yl)valeric acid ; 5-(dithiolan-3-yl)valeric acid ; 5-[3-(1,2-dithiolanyl)]pentanoic acid ; 6-thioc­tic acid ; 6-thi­ot­ic acid ; 6,8-thioctic acid ; 6,8-thiotic acid ; α-Lipoic acid ; lipon­ic acid ; α-lipoic acid 1,2-Dithiolane-3-valeric acid 1,2-Dithiolane-3-valeric acid, (±)- 1,2-Dithiolane-3-valeric acid, (±)- 1077-24-7 [RN] 1077-27-6 [RN] 1077-28-7 [RN] 1200-22-2 [RN] 122410 [Beil­stein] 1483-55-2 [RN] 41274-09-3 [RN] 462-20-4 [RN] 5-(1,2)Dithiolan-3-yl-pentanoic acid 5-(1,2-dithiolan-3-yl)-pentanoate 5-(1,2-DITHI­OLAN-3-YL)VALER­IC ACID 5-(3-dithiolanyl)pentanoic acid 5-(Dithiolan-3-yl)pentanoic acid 5-(Dithiolan-3-yl)valeric acid 5-[1,2]Dithiolan-3-yl-pentanoic acid 5-[3-(1,2-Dithiolanyl)]pentanoic Acid 6,8-bis(sulfanylidene)octanoic acid 6,8-Dithiooctanoic acid 6,8-THIOC­TIC ACID 6,8-Thiotic acid 6-Thioc­tic acid 6-Thi­ot­ic acid 73Y7P0K73Y 81853 [Beil­stein] Acid, α-Lipoic a-Lipoic Acid Alphaflam AlphaLi­pogam­ma Alphalipoic acid Alphalipoic-acid alphaV­i­bolex Azulipont Bile­tan Bile­tan (trade name) bio­mo lipon bio­molipon bio­­mo-lipon BR-72974 D008063 DL-1,2-Dithi­olan-3-vale­ri­ansaeure [Ger­man] DL-1,2-Dithi­olan-3-vale­ri­ansaeure DL-1,2-Dithi­olane-3-pen­tanoic acid DL-1,2-Dithi­olane-3-valer­ic acid DL-6,8-Dithiooc­tanoic acid DL-6,8-Thioc­tic acid DL-6-Thioc­tic acid dl-Lipoic acid dl-thioc­ti­­cacid DL-α-Lipoic acid DL-α-Lipoic Acid DL-α-Lipoic Acid, Dihy­­dro- duralipon espa lipon espalipon espa-lipon Fenint Injekt, Thiogam­ma Juthi­ac Lip(S2) lipoate lipoic acid (LA) Lipoicacid lipon­ic acid Liposan Lipoth­ion MFCD00005474 [MDL num­ber] MFCD01631142 [MDL num­ber] MFCD01863481 MTW αlipon­saure MTWAl­phalipon­saure MTW-αlipon­saure Neuri­um OR-4010 Phar­­makon1600-01503941 Pleomix α Pleomix α N Pleomix­Al­pha Pleomix­Al­pha N Pleomix-α Pleomix-α N rac a-lipoic acid Rac-lipoate RLA R-LA Thioctacid Thioctacide T Thioc­tansaeure Thioc­tic acid d-form Thioc­tic acid dl-form Thioc­tic acid, dl-form Thioct­saeure Thioct­san Thiok­t­saeure Thiooc­tic acid Thiotomin [Trade name] Tioc­ti­dasi Trom­lipon Ver­la Lipon Ver­laLipon Ver­la-Lipon α Lipogam­ma α Lipoic α Lipoic Acid α Lipoic Acid (en) α Vibolex α-Lipogam­­ma α-lipoic acid α-Lipoic acid α-Lipoic acid α-lipon­ic acid α-Lipon­ic acid α-Lipon­saeure [Ger­man] α-Lipon­saeure α-Vibolex

Mol­e­c­u­lar Structure

SMILES

C1CSSC1CCCCC(=O)O

Std­InChI

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

Std­InChIKey

AGBQKN­BQESQN­JD-UHF­F­­FAOYSA-N

Mol­e­c­u­lar Formula

C8H14O2S2

Mol­e­c­u­lar Weight

206.326

MDL Number

MFCD01631142

Prop­er­ties

Appear­ance

Yel­low crys­tal pow­der

Melt­ing Point

46~50℃

Safe­ty Data

RIDADR

NONH for all modes of trans­port

WGK Germany

3 

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our R-(+)-alpha-Lipoic acid CAS 1200-22-2

Stan­dard

Enter­prise stan­dard

Iden­ti­fi­ca­tion Methods

HNMR,HPLC

Puri­ty

99%min

Opti­cal purity

99%min

Spe­cif­ic Opti­cal Rotation

+117°~+112°

Heavy Met­als

10ppm max

Loss on Drying

0.5%max

Residue on Ignition

0.2%max

Pack­age

Accord­ing to cus­tomer require­ments to pack­ag­ing

Stor­age

Under the room tem­per­a­ture and away from light

Gen­er­al View of Documents

Appli­ca­tion

Lipoic acid (LA), also known as alpha lipoic acid (ALA) and thioc­tic acid is an organosul­fur com­pound which is wide­ly used as a dietary sup­ple­ment in some coun­tries mar­ket­ed as an antiox­i­dant and is avail­able as a phar­ma­ceu­ti­cal drug in oth­er coun­tries. Alpha-Lipoic Acid bulk mate­r­i­al avail­able today is (R/S) or (+/-) Alpha Lipoic Acid (ALA), mean­ing it con­tains a 50/50 mix­ture of (R-Lipoic) and unnat­ur­al (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found any­where in nature, is a byprod­uct of chem­i­cal syn­the­sis. Research indi­cates that not only does the human body have dif­fi­cul­ty absorb­ing this unnat­ur­al ver­sion, it may inhib­it the most essen­tial prop­er­ties of the R-Lipoic Acid form ! The ​“R” form (R Lipoic) is con­sid­ered the ​“eutomer” (the bio­log­i­cal­ly supe­ri­or form) of Alpha Lipoic Acid, since it is iden­ti­cal to that pro­duced by the body. Research indi­cates R-Lipoic Acid is respon­si­ble for most of the ben­e­fi­cial effects attrib­uted to ALA. While R Lipoic Acid is the obvi­ous choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its ​“free-acid” form has two major draw­backs : sta­bil­i­ty and bioavail­abil­i­ty. With­out spe­cial pro­cess­ing, R-Lipoic Acid is high­ly unsta­ble and dif­fi­cult to absorb. In fact, phar­ma­co­ki­net­ic data reveal that while Alpha Lipoic Acid has a very low absorp­tion rate, unsta­bi­lized R-Lipoic Acid is absorbed even worse ! As one of the largest fine chem­i­cal devel­op­ers glob­al­ly, Wat­son solved the sta­bil­i­ty issue by bring­ing in two oth­er derivates R(+)-Alpha Lipoic Acid Sodi­um CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8, being one of the world’s largest pur­vey­or of com­mer­cial­ly pro­duced sta­bi­lized R-Lipoic Acid mate­ri­als. You know check here to know more about our two prod­ucts, R (+)-Alpha Lipoic Acid Sodi­um CAS 176110-81-9 : https://​www​.wat​son​-int​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​s​o​d​i​u​m​-​c​a​s​-​1​7​6​1​1​0​-​8​1​-9/ R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8 : https://​www​.wat​son​-int​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​t​r​o​m​e​t​h​a​m​i​n​e​-​s​a​l​t​-​c​a​s​-​1​4​3​5​8​-​9​0​-8/

Links

This prod­uct is devel­oped by our RD com­pa­ny Ulcho Bio­chem­i­cal Ltd(http://​www​.ulcho​.com/), and here is the cor­re­spond­ing linkhttp://​www​.ulcho​.com/​r​-​a​l​p​h​a​-​l​i​p​o​i​c​-​a​c​i​d​-​c​a​s​-​1​2​0​0​-​2​2​-2/

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