R-(+)-alpha-Lipoic acid CAS 1200-22-2

R-(+)-alpha-Lipoic acid CAS 1200-22-2

Identification
Properties
Safety Data
Specifications andamp; Other Information
Links

Identification

CAS Number

1200-22-2

Name

R-(+)-alpha-Lipoic acid

Synonyms

(±)-1,2-Dithiolane-3-valeric acid
1,2-Dithiolane-3-pentanoic acid [ACD/Index Name]
200-534-6 [EINECS]
5-(1,2-Dithiolan-3-yl)pentanoic acid [ACD/IUPAC Name]
5-(1,2-Dithiolan-3-yl)pentansäure [German] [ACD/IUPAC Name]
6,8-Dihydrothioctic acid
Acide 5-(1,2-dithiolan-3-yl)pentanoïque [French] [ACD/IUPAC Name]
DL-Thioctic acid
lipoic acid [Wiki]
Thioctic acid [JAN]
UNII:73Y7P0K73Y
(+)-α-Lipoic acid
(±)-1,2-Dithiolane-3-pentanoic acid
(±)-1,2-Dithiolane-3-pentanoic acid
(±)-1,2-Dithiolane-3-valeric acid
(±)-Lipoic acid
(±)-Lipoic acid
(±)-Thioctic acid
(±)-α-Lipoic acid
(±)-α-Lipoic acid
(R)-(+)-lipoic acid
(R)-1,2-Dithiolane-3-pentanoic acid
(R)-6,8-thioctic acid
(R)-lipoate
(R)-lipoic acid
(RS)-Lipoic acid
(RS)-α-Lipoic acid
[1077-27-6]
[1077-28-7]
1,2-Dithiolane-3-pentanoic acid, (±)-
1,2-Dithiolane-3-pentanoic acid, (±)-
1,2-dithiolane-3-pentanoic acid; 1,2-dithiolane-3-valeric acid; 5-(1,2-dithiolan-3-yl)valeric acid; 5-(dithiolan-3-yl)valeric acid; 5-[3-(1,2-dithiolanyl)]pentanoic acid; 6-thioctic acid; 6-thiotic acid; 6,8-thioctic acid; 6,8-thiotic acid; Acetate-replacing factor; α-Lipoic acid; α-Lipons??ure; Biletan; liponic acid; Thioctans??ure; Thioctic acid; Thiocts??ure; Thiokts??ure; ??-lipoic acid
1,2-dithiolane-3-pentanoic acid; 1,2-dithiolane-3-valeric acid; 5-(1,2-dithiolan-3-yl)valeric acid; 5-(dithiolan-3-yl)valeric acid; 5-[3-(1,2-dithiolanyl)]pentanoic acid; 6-thioctic acid; 6-thiotic acid; 6,8-thioctic acid; 6,8-thiotic acid; α-Lipoic acid; liponic acid; α-lipoic acid
1,2-Dithiolane-3-valeric acid
1,2-Dithiolane-3-valeric acid, (±)-
1,2-Dithiolane-3-valeric acid, (±)-
1077-24-7 [RN]
1077-27-6 [RN]
1077-28-7 [RN]
1200-22-2 [RN]
122410 [Beilstein]
1483-55-2 [RN]
41274-09-3 [RN]
462-20-4 [RN]
5-(1,2)Dithiolan-3-yl-pentanoic acid
5-(1,2-dithiolan-3-yl)-pentanoate
5-(1,2-DITHIOLAN-3-YL)VALERIC ACID
5-(3-dithiolanyl)pentanoic acid
5-(Dithiolan-3-yl)pentanoic acid
5-(Dithiolan-3-yl)valeric acid
5-[1,2]Dithiolan-3-yl-pentanoic acid
5-[3-(1,2-Dithiolanyl)]pentanoic Acid
6,8-bis(sulfanylidene)octanoic acid
6,8-Dithiooctanoic acid
6,8-THIOCTIC ACID
6,8-Thiotic acid
6-Thioctic acid
6-Thiotic acid
73Y7P0K73Y
81853 [Beilstein]
Acid, α-Lipoic
a-Lipoic Acid
Alphaflam
AlphaLipogamma
Alphalipoic acid
Alphalipoic-acid
alphaVibolex
Azulipont
Biletan
Biletan (trade name)
biomo lipon
biomolipon
biomo-lipon
BR-72974
D008063
DL-1,2-Dithiolan-3-valeriansaeure [German]
DL-1,2-Dithiolan-3-valeriansaeure
DL-1,2-Dithiolane-3-pentanoic acid
DL-1,2-Dithiolane-3-valeric acid
DL-6,8-Dithiooctanoic acid
DL-6,8-Thioctic acid
DL-6-Thioctic acid
dl-Lipoic acid
dl-thiocticacid
DL-α-Lipoic acid
DL-α-Lipoic Acid
DL-α-Lipoic Acid, Dihydro-
duralipon
espa lipon
espalipon
espa-lipon
Fenint
Injekt, Thiogamma
Juthiac
Lip(S2)
lipoate
lipoic acid (LA)
Lipoicacid
liponic acid
Liposan
Lipothion
MFCD00005474 [MDL number]
MFCD01631142 [MDL number]
MFCD01863481
MTW αliponsaure
MTWAlphaliponsaure
MTW-αliponsaure
Neurium
OR-4010
Pharmakon1600-01503941
Pleomix α
Pleomix α N
PleomixAlpha
PleomixAlpha N
Pleomix-α
Pleomix-α N
rac a-lipoic acid
Rac-lipoate
RLA
R-LA
Thioctacid
Thioctacide T
Thioctansaeure
Thioctic acid d-form
Thioctic acid dl-form
Thioctic acid, dl-form
Thioctsaeure
Thioctsan
Thioktsaeure
Thiooctic acid
Thiotomin [Trade name]
Tioctidasi
Tromlipon
Verla Lipon
VerlaLipon
Verla-Lipon
α Lipogamma
α Lipoic
α Lipoic Acid
α Lipoic Acid (en)
α Vibolex
α-Lipogamma
α-lipoic acid
α-Lipoic acid
α-Lipoic acid
α-liponic acid
α-Liponic acid
α-Liponsaeure [German]
α-Liponsaeure
α-Vibolex

Molecular Structure

Structure of R-(+)-alpha-Lipoic acid CAS 1200-22-2

Structure of R-(+)-alpha-Lipoic acid CAS 1200-22-2

SMILES

C1CSSC1CCCCC(=O)O

StdInChI

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

StdInChIKey

AGBQKNBQESQNJD-UHFFFAOYSA-N

Molecular Formula

C8H14O2S2

Molecular Weight

206.326

MDL Number

MFCD01631142

Properties

Appearance

Yellow crystal powder

Melting Point

46~50℃

Safety Data

RIDADR

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our R-(+)-alpha-Lipoic acid CAS 1200-22-2

Standard

Enterprise standard

Identification Methods

HNMR,HPLC

Purity

99%min

Optical purity

99%min

Specific Optical Rotation

+117°~+112°

Heavy Metals

10ppm max

Loss on Drying

0.5%max

Residue on Ignition

0.2%max

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light

Application

Lipoic acid (LA), also known as alpha lipoic acid (ALA) and thioctic acid is an organosulfur compound which is widely used as a dietary supplement in some countries marketed as an antioxidant and is available as a pharmaceutical drug in other countries.

Alpha-Lipoic Acid bulk material available today is (R/S) or (+/-) Alpha Lipoic Acid (ALA), meaning it contains a 50/50 mixture of (R-Lipoic) and unnatural (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found anywhere in nature, is a byproduct of chemical synthesis. Research indicates that not only does the human body have difficulty absorbing this unnatural version, it may inhibit the most essential properties of the R-Lipoic Acid form!

The “R” form (R Lipoic) is considered the “eutomer” (the biologically superior form) of Alpha Lipoic Acid, since it is identical to that produced by the body. Research indicates R-Lipoic Acid is responsible for most of the beneficial effects attributed to ALA.

While R Lipoic Acid is the obvious choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its “free-acid” form has two major drawbacks: stability and bioavailability. Without special processing, R-Lipoic Acid is highly unstable and difficult to absorb. In fact, pharmacokinetic data reveal that while Alpha Lipoic Acid has a very low absorption rate, unstabilized R-Lipoic Acid is absorbed even worse!

As one of the largest fine chemical developers globally, Watson solved the stability issue by bringing in two other derivates R(+)-Alpha Lipoic Acid Sodium CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8, being one of the world’s largest purveyor of commercially produced stabilized R-Lipoic Acid materials.

You know check here to know more about our two products,

R (+)-Alpha Lipoic Acid Sodium CAS 176110-81-9https://www.watson-int.com/r-alpha-lipoic-acid-sodium-cas-176110-81-9/

R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8: https://www.watson-int.com/r-alpha-lipoic-acid-tromethamine-salt-cas-14358-90-8/

Links

This product is developed by our RD company Ulcho Biochemical Ltd(http://www.ulcho.com/), and here is the corresponding linkhttp://www.ulcho.com/r-alpha-lipoic-acid-cas-1200-22-2/

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