Identification
Properties
Safety Data
Specifications andamp ; Other Information
Links
Identification
CAS Number
62-46-4
Name
Lipoic acid
Synonyms
(+)-Thioctic acid (+)-α-Lipoic acid (R)-(+)-lipoic acid (R)-(+)-α-Lipoic acid (R)-α-Lipoic Acid 1,2-Dithiolane-3-pentanoic acid, (
3R)- [
ACD/Index Name] 5-[(
3R)-1,2-Dithiolan-3-yl]pentanoic acid [
ACD/
IUPAC Name] 5-[(
3R)-1,2-Dithiolan-3-yl]pentansäure [German] [
ACD/
IUPAC Name] 5-[3-(1,2-Dithiolanyl)]pentanoic Acid 5-19-07-00237 [Beilstein] 62-46-4 [
RN] Acetate Replacing Factor Acide 5-[(
3R)-1,2-dithiolan-3-yl]pentanoïque [French] [
ACD/
IUPAC Name] a-Lipoic Acid a-Liponic acid d-[3-(1,2-Dithiacyclopentyl)]pentanoic Acid lipoic acid [Wiki] Lipoicin Thioctan Thioctic acid [
JAN] Tioctan α-Lipoic acid δ-[3-(1,2-dithiacyclopentyl)]pentanoic acid (+)-α-Lipoate (R)-1,2-Dithiolane-3-pentanoate 1,2-Dithiolane-3-pentanoate 1,2-Dithiolane-3R-pentanoate 1,2-Dithiolane-3-valerate 5-(1,2-Dithiolan-3-yl)valerate 5-(Dithiolan-3-yl)valerate 5-(Dithiolan-3-yl)valeric acid 5-[3-(1,2-dithiolanyl)]pentanoate 6,8-Dithiooctanoate 6,8-Thioctate 6,8-Thiotate 6-Thioctate 6-Thiotate
LIP liponate liponic acid Thioctate Thiooctanoate α Lipoate α Lipoic Acid α-Lipoate α-Liponate δ-[3-(1,2-dithiacyclopentyl)]pentanoate andamp;α;-lipoic acid (+)-1,2-Dithiolane-3-valeric acid (
3R)-1,2-Dithiolane-3-pentanoic acid (R)-(+)-1,2-Dithiolane-3-pentanoic acid (R)-(+)-Lipoate (R)-1,2-Dithiolane-3-pentanoic acid (R)-1,2-Dithiolane-3-Valeric Acid (R)-1,2-Dithiolane-3-ValericAcid (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid (R)-6,8-thioctic acid (R)-lipoic acid (S)-(???)-lipoic acid (S)-1,2-dithiolane-3-pentanoic acid (S)-lipoic acid (S)-α-Lipoic Acid [1077-28-7] [1200-22-2] [4547-02-8] 1,2-Dithiolane-3-pentanoic acid, (R)- 1,2-Dithiolane-3R-pentanoic acid 1,2-Dithiolane-3-valeric acid
‘1200-22-2 1200-22-2 ; 62-46-4 214-071-2 [
EINECS] 5-(1,
2-DITHIOLAN-3-YL)
VALERIC ACID 5-[(
3R)-3-dithiolanyl]pentanoic acid 5-[(
3R)-dithiolan-3-yl]pentanoic acid 5-[(
3R)-dithiolan-3-yl]valeric acid 5-19-07-00237 (Beilstein Handbook Reference) [Beilstein] 6,8-Dithiooctanoic acid 6,
8-THIOCTIC ACID 6,8-Thiotic acid 6-Thioctic acid 6-Thiotic acid 81851 [Beilstein] Acetate-replacing factor Biletan
BR-68233 CHEMBL134342 EINECS 200-534-6 Heparlipon L-1,2-dithiolane 3-valeric acid L-6,8-thioctic acid L-6-thioctic acid Lip(
S2) lipoate Liposan Lipothion Lopac0_001129
LPA L-Thioctic acid
MFCD00005474 [
MDL number]
MFCD01631142 [
MDL number]
NCGC00094396-03 Protogen A Pyruvate oxidation factor R-(+)-1,2-Dithiolane-3-pentanoic acid R-(+)-Lipoic acid R-(+)-Thioctic acid R-(+)-α-Lipoic acid R(+)-α-LIPOIC
ACID r-(+)-α-lipoicacid
RLA R-LA R-Lipoate R-Lipoic acid R-α-Lipoic acid
SLA S-LA
STOCK1N-43250 Thioctacid Thioctanoic acid Thioctic acid [
JAN] Thioctic acid d-form thioctic acid l-form
THIOCTIC ACID, (+)- Thioctsan Thioktsaeure [German] Thioktsaeure Thioktsaeure [German] Thionordazepam Thiooctanoic acid Thiotomin [Trade name] Tioctacid Tioctic Acid Tioctidasi Tioctidasi acetate replacing factor
TL8004155 UNII :
VLL71EBS9Z UNII-73Y7P0K73Y UNII-VLL71EBS9Z α-lipoic acid α-Lipoic acid α-liponic acid α-Liponsaeure [German] α-Liponsaeure α-Liponsaeure [German] 硫辛酸 [Chinese]
Molecular Structure
Structure of Lipoic acid CAS 62-46-4
SMILES
C1CSS[C@@H]
1CCCCC(=O)O
StdInChI
InChI=
1S/
C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
StdInChIKey
AGBQKNBQESQNJD-SSDOTTSWSA-N Molecular Formula
C8H14O2S2 Molecular Weight
206.32
EINECS
200-534-6
Properties
Appearance
Pale yellow crystalline
Melting Point
48-52 °C(lit.)
Safety Data
WGK Germany
3
Specifications and Other Information of Our Lipoic acid CAS 62-46-4
Standard
Enterprise standard
Identification Methods
HPLC Purity
98%min
Package
According to customer requirements to packaging
Storage
Under the room temperature and away from light
Application
Lipoic acid (
LA), also known as alpha lipoic acid (
ALA) and thioctic acid is an organosulfur compound which is widely used as a dietary supplement in some countries marketed as an antioxidant and is available as a pharmaceutical drug in other countries. Alpha-Lipoic Acid bulk material available today is (R/S) or (+/-) Alpha Lipoic Acid (
ALA), meaning it contains a 50/50 mixture of (R-Lipoic) and unnatural (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found anywhere in nature, is a byproduct of chemical synthesis. Research indicates that not only does the human body have difficulty absorbing this unnatural version, it may inhibit the most essential properties of the R-Lipoic Acid form ! The
“R” form (R Lipoic) is considered the
“eutomer” (the biologically superior form) of Alpha Lipoic Acid, since it is identical to that produced by the body. Research indicates R-Lipoic Acid is responsible for most of the beneficial effects attributed to
ALA. While R Lipoic Acid is the obvious choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its
“free-acid” form has two major drawbacks : stability and bioavailability. Without special processing, R-Lipoic Acid is highly unstable and difficult to absorb. In fact, pharmacokinetic data reveal that while Alpha Lipoic Acid has a very low absorption rate, unstabilized R-Lipoic Acid is absorbed even worse ! As one of the largest fine chemical developers globally, Watson solved the stability issue by bringing in two other derivates R(+)-Alpha Lipoic Acid Sodium
CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt
CAS 14358-90-8, being one of the world’s largest purveyor of commercially produced stabilized R-Lipoic Acid materials. You know check here to know more about our three products :
R (+)-Alpha Lipoic Acid Sodium CAS 176110-81-9 :
https://www.watson-int.com/r-alpha-lipoic-acid-sodium-cas-176110-81-9/
R-(+)-alpha-Lipoic acid CAS 1200-22-2 :
https://www.watson-int.com/r-alpha-lipoic-acid-cas-1200-22-2/
R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8 :
https://www.watson-int.com/r-alpha-lipoic-acid-tromethamine-salt-cas-14358-90-8/
Links
This product is developed by our
RD company Ulcho Biochemical Ltd(
http://www.ulcho.com/), and here is the corresponding link
http://www.ulcho.com/lipoic-acid-cas-62-46-4/
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