Lipoic acid CAS 62-46-4

Identification Properties Safety Data Specifications andamp; Other Information Links

Identification

CAS Number

62-46-4

Name

Lipoic acid

Synonyms

(+)-Thioctic acid (+)-α-Lipoic acid (R)-(+)-lipoic acid (R)-(+)-α-Lipoic acid (R)-α-Lipoic Acid 1,2-Dithiolane-3-pentanoic acid, (3R)- [ACD/Index Name] 5-[(3R)-1,2-Dithiolan-3-yl]pentanoic acid [ACD/IUPAC Name] 5-[(3R)-1,2-Dithiolan-3-yl]pentansäure [German] [ACD/IUPAC Name] 5-[3-(1,2-Dithiolanyl)]pentanoic Acid 5-19-07-00237 [Beilstein] 62-46-4 [RN] Acetate Replacing Factor Acide 5-[(3R)-1,2-dithiolan-3-yl]pentanoïque [French] [ACD/IUPAC Name] a-Lipoic Acid a-Liponic acid d-[3-(1,2-Dithiacyclopentyl)]pentanoic Acid lipoic acid [Wiki] Lipoicin Thioctan Thioctic acid [JAN] Tioctan α-Lipoic acid δ-[3-(1,2-dithiacyclopentyl)]pentanoic acid (+)-α-Lipoate (R)-1,2-Dithiolane-3-pentanoate 1,2-Dithiolane-3-pentanoate 1,2-Dithiolane-3R-pentanoate 1,2-Dithiolane-3-valerate 5-(1,2-Dithiolan-3-yl)valerate 5-(Dithiolan-3-yl)valerate 5-(Dithiolan-3-yl)valeric acid 5-[3-(1,2-dithiolanyl)]pentanoate 6,8-Dithiooctanoate 6,8-Thioctate 6,8-Thiotate 6-Thioctate 6-Thiotate LIP liponate liponic acid Thioctate Thiooctanoate α Lipoate α Lipoic Acid α-Lipoate α-Liponate δ-[3-(1,2-dithiacyclopentyl)]pentanoate andamp;α;-lipoic acid (+)-1,2-Dithiolane-3-valeric acid (3R)-1,2-Dithiolane-3-pentanoic acid (R)-(+)-1,2-Dithiolane-3-pentanoic acid (R)-(+)-Lipoate (R)-1,2-Dithiolane-3-pentanoic acid (R)-1,2-Dithiolane-3-Valeric Acid (R)-1,2-Dithiolane-3-ValericAcid (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid (R)-6,8-thioctic acid (R)-lipoic acid (S)-(???)-lipoic acid (S)-1,2-dithiolane-3-pentanoic acid (S)-lipoic acid (S)-α-Lipoic Acid [1077-28-7] [1200-22-2] [4547-02-8] 1,2-Dithiolane-3-pentanoic acid, (R)- 1,2-Dithiolane-3R-pentanoic acid 1,2-Dithiolane-3-valeric acid ‘1200-22-2 1200-22-2; 62-46-4 214-071-2 [EINECS] 5-(1,2-DITHIOLAN-3-YL)VALERIC ACID 5-[(3R)-3-dithiolanyl]pentanoic acid 5-[(3R)-dithiolan-3-yl]pentanoic acid 5-[(3R)-dithiolan-3-yl]valeric acid 5-19-07-00237 (Beilstein Handbook Reference) [Beilstein] 6,8-Dithiooctanoic acid 6,8-THIOCTIC ACID 6,8-Thiotic acid 6-Thioctic acid 6-Thiotic acid 81851 [Beilstein] Acetate-replacing factor Biletan BR-68233 CHEMBL134342 EINECS 200-534-6 Heparlipon L-1,2-dithiolane 3-valeric acid L-6,8-thioctic acid L-6-thioctic acid Lip(S2) lipoate Liposan Lipothion Lopac0_001129 LPA L-Thioctic acid MFCD00005474 [MDL number] MFCD01631142 [MDL number] NCGC00094396-03 Protogen A Pyruvate oxidation factor R-(+)-1,2-Dithiolane-3-pentanoic acid R-(+)-Lipoic acid R-(+)-Thioctic acid R-(+)-α-Lipoic acid R(+)-α-LIPOIC ACID r-(+)-α-lipoicacid RLA R-LA R-Lipoate R-Lipoic acid R-α-Lipoic acid SLA S-LA STOCK1N-43250 Thioctacid Thioctanoic acid Thioctic acid [JAN] Thioctic acid d-form thioctic acid l-form THIOCTIC ACID, (+)- Thioctsan Thioktsaeure [German] Thioktsaeure Thioktsaeure [German] Thionordazepam Thiooctanoic acid Thiotomin [Trade name] Tioctacid Tioctic Acid Tioctidasi Tioctidasi acetate replacing factor TL8004155 UNII:VLL71EBS9Z UNII-73Y7P0K73Y UNII-VLL71EBS9Z α-lipoic acid α-Lipoic acid α-liponic acid α-Liponsaeure [German] α-Liponsaeure α-Liponsaeure [German] 硫辛酸 [Chinese]

Molecular Structure

Structure of Lipoic acid CAS 62-46-4

SMILES

C1CSS[C@@H]1CCCCC(=O)O

StdInChI

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1

StdInChIKey

AGBQKNBQESQNJD-SSDOTTSWSA-N

Molecular Formula

C8H14O2S2

Molecular Weight

206.32

EINECS

200-534-6

Properties

Appearance

Pale yellow crystalline

Melting Point

48-52 °C(lit.)

Safety Data

WGK Germany

Specifications and Other Information of Our Lipoic acid CAS 62-46-4

Standard

Enterprise standard

Identification Methods

HPLC

Purity

98%min

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light

Application

Lipoic acid (LA), also known as alpha lipoic acid (ALA) and thioctic acid is an organosulfur compound which is widely used as a dietary supplement in some countries marketed as an antioxidant and is available as a pharmaceutical drug in other countries. Alpha-Lipoic Acid bulk material available today is (R/S) or (+/-) Alpha Lipoic Acid (ALA), meaning it contains a 50/50 mixture of (R-Lipoic) and unnatural (S-Lipoic) Lipoic Acid. The S-Lipoic Acid form, which is not found anywhere in nature, is a byproduct of chemical synthesis. Research indicates that not only does the human body have difficulty absorbing this unnatural version, it may inhibit the most essential properties of the R-Lipoic Acid form! The “R” form (R Lipoic) is considered the “eutomer” (the biologically superior form) of Alpha Lipoic Acid, since it is identical to that produced by the body. Research indicates R-Lipoic Acid is responsible for most of the beneficial effects attributed to ALA. While R Lipoic Acid is the obvious choice over Alpha Lipoic Acid, pure R-Lipoic Acid in its “free-acid” form has two major drawbacks: stability and bioavailability. Without special processing, R-Lipoic Acid is highly unstable and difficult to absorb. In fact, pharmacokinetic data reveal that while Alpha Lipoic Acid has a very low absorption rate, unstabilized R-Lipoic Acid is absorbed even worse! As one of the largest fine chemical developers globally, Watson solved the stability issue by bringing in two other derivates R(+)-Alpha Lipoic Acid Sodium CAS 176110-81-9 and R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8, being one of the world’s largest purveyor of commercially produced stabilized R-Lipoic Acid materials. You know check here to know more about our three products: R (+)-Alpha Lipoic Acid Sodium CAS 176110-81-9: https://www.watson-int.com/r-alpha-lipoic-acid-sodium-cas-176110-81-9/ R-(+)-alpha-Lipoic acid CAS 1200-22-2: https://www.watson-int.com/r-alpha-lipoic-acid-cas-1200-22-2/ R-alpha-Lipoic acid tromethamine salt CAS 14358-90-8: https://www.watson-int.com/r-alpha-lipoic-acid-tromethamine-salt-cas-14358-90-8/