(S)-Amlodipine CAS 103129-82-4

Iden­ti­fi­ca­tion

CAS Number

103129-82-4

Name

(S)-Amlodipine

Syn­onyms

(S)-amlodipine 3,5-pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-eth­yl 5-methyl ester, (4S)- 3-Eth­yl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate amlodip­inum (-)-(s)-Amlodipine (4S)-; l-Amlodip­ine ; Levoam­lodip­ine Besy­late ; (S)-Amlodipine (4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-eth­yl 5-methyl ester Amlodip­ine Lev­am­lodip­ine Levoam­lodip­ine Levoam­lodip­ine Besy­late

Mol­e­c­u­lar Structure

SMILES

Clc1ccccc1[C@H]2C(=C(/N/C(=C2/C(=O)OCC)COC­CN)C)C(=O)OC

Std­InChI

InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1

Std­InChIKey

HTIQEAQV­­CY­­TUBX-KRWDZBQOSA-N

Mol­e­c­u­lar Formula

C20H25N2O5Cl

Mol­e­c­u­lar Weight

408.88

Prop­er­ties

Appear­ance

Off white to white pow­der

Sol­u­bil­i­ty

Free sol­u­ble in methanol and ethanol and slight­ly sol­u­ble in water

Flash Point

272.617 °C

Boil­ing Point

527.161°C at 760 mmHg

Den­si­ty

1.227g/ml

Safe­ty Data

Per­son­al Pro­tec­tive Equipment

Eye­shields, Gloves

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our (S)-Amlodipine CAS 103129-82-4

Assay

98.5%min

Opti­cal Purity

98.5%min

Iden­ti­fi­ca­tions

IR, HPLC

Opti­cal Rotation

-24.2~-28.3°

Water

5.5% max

Resid­ual Solvents

Ethanol : 0.5% max

Par­ti­cle Size

80 mesh max

Relat­ed Substances

1.0% max

Residue on Ignition

0.1% max

Heavy Met­als

20ppm max

Pro­duc­tiv­i­ty

500kg/​month

Stor­age

Room tem­per­a­ture away from light

Known Appli­ca­tion

Low­er­ing blood pres­sure, used for hyper­ten­sion, angi­na, car­dio­vas­cu­lar dis­ease.

Wat­­son-Int Link

http://​wat​son​-int​.com/​(​S​)​-​A​m​l​o​d​i​p​i​n​e​_​C​A​S​_​1​0​3​1​2​9​-​8​2​-​4​.​h​tml