Identification
CAS Number
125494-59-9, 84485-00-7, 10665-56-0Name
Sibutramine hydrochloride monohydrateMolecular Structure
Synonyms
1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate (±)-1-(p-Chlorophenyl)-a-isobutyl-N,N-dimethylcyclobutanemethylamine hydrochloride monohydrate 1-[1-(4-Chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrochloride hydrate 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride hydrate cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, hydrate (1:1:1) Sibutramine Hydrochloride 1-(4-Chlorophenyl)-N,N-dimethyl-¦Á-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrate hydrochloride 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride Meridia ReductilMDL Number
MFCD04039806Molecular Formula
C17H26ClN·HCl·H2OMolecular Weight
334.32Properties
Appearance
Off-white to white crystalline powderSolubility
DMSO : andgt;30 mg/mL H2O : insolubleMelting Point
190-200 ºCFlash Point
161 °CBoiling Point
342.6 °C at 760 mmHgSafety Data
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filterWGK Germany
3Specifications and Other Information of Our Sibutramine hydrochloride monohydrate CAS 125494-59-9
Assay
98%minIdentification Methods
IRAssay
98% minTLC
One spot maxWater
5.0%-6.5%PH
4.0-6.0Heavy Metals
20 ppm maxResidue on Ignition
0.1% maxBiochem/Physiol Actions
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.Productivity
500kg-1000kg/monthGeneral View of Doccuments
Sibutramine hydrochloride monohydrate CAS 125494-59-9 IR
