Identification
CAS Number
201341-05-1
Name
Tenofovir disoproxil
Synonyms
({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}méthyl)phosphonate de bis{[(isopropoxycarbonyl)oxy]méthyle} [French] [ACD/IUPAC Name]
(R)-(((((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate)
201341-05-1 [RN]
Bis(((isopropoxycarbonyl)oxy)methyl) (((1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonate
bis({[(propan-2-yloxy)carbonyl]oxy}methyl) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
Bis{[(isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate [ACD/IUPAC Name]
Bis{[(isopropoxycarbonyl)oxy]methyl} ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
Bis{[(isopropoxycarbonyl)oxy]methyl} {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl]oxy}methylphosphonate
Bis{[(isopropoxycarbonyl)oxy]methyl}-({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonat [German] [ACD/IUPAC Name]
Carbonic acid, [[[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl][[[(1-methylethoxy)carbonyl]oxy]methoxy]phosphinyl]oxy]methyl 1-methylethyl ester [ACD/Index Name]
MFCD00952920 [MDL number]
Tenofovir disoproxil
({[(1R)-2-(6-aminopurin-9-yl)-isopropoxy]methyl}{[(methylethyl)oxycarbonyloxy]methoxy}carbonyloxy)methyl (methylethoxy)formate
(R)-(((((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl dicarbonate
[(R)-2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester
[[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(isopropoxycarbonyloxymethoxy)phosphoryl]oxymethyl isopropyl carbonate
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
[201341-05-1]
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide
201341-05-1 (free)
202138-50-9 (1:1 FUMARATE SALT)
9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine
9-[(R)-2-[[Bis[[(isopropoxycarbonyl)oxy] methoxy]phosphinyl]methoxy]propyl]adenine
BIS({[(PROPAN-2-YLOXY)CARBONYL]OXY}METHYL) {[(2R)-1-(6-AMINO-9H-PURIN-9-YL)PROPAN-2-YL]OXY}METHANEPHOSPHONATE
Bis(isopropyloxymethylcarbonyl)PMPA
Bis(POC)PMPA
carbonic acid [[(1R)-2-(6-amino-9-purinyl)-1-methylethoxy]methyl-[(isopropoxy-oxomethoxy)methoxy]phosphoryl]oxymethyl isopropyl ester
carbonic acid [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(isopropoxycarbonyloxymethoxy)phosphoryl]oxymethyl isopropyl ester
carbonic acid [1-(6-aminopurin-9-yl)propan-2-yloxymethyl-[[oxo(propan-2-yloxy)methoxy]methoxy]phosphoryl]oxymethyl propan-2-yl ester
GS 4331-05 (1:1 Fumarate salt)
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:63717
PMPA prodrug
QA-8716
Tenofovir (Disoproxil)
tenofovir bis(isopropyloxycarbonyloxymethyl) ester
Tenofovir Disoproxil free base
TENOFOVIR DISOPROXIL[ADENINE-8-3H]
SMILES
C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C
StdInChI
InChI=1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m1/s1
StdInChIKey
JFVZFKDSXNQEJW-CQSZACIVSA-N
Molecular Formula
C19H30N5O10P
Molecular Weight
519.44
MDL Number
MFCD00952920
Properties
Appearance
White powder
Safety Data
RIDADR
NONH for all modes of transport
WGK Germany
3
Specifications and Other Information of Our Tenofovir disoproxil CAS 201341-05-1
Identification Methods
HNMR, HPLC
Available document
GMP, DMF
Purity
98% min
Shelf Life
2 years
Storage
Under room temperature away from light
Known Application
Often used as nucleotide antiviral drugs.
