Identification Properties Safety Data Specifications and Other Information Links

Identification

CAS Number

745-65-3

Name

Alprostadil

Synonyms

(-)-Prostaglandin E1 (11a,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid [ACD/IUPAC Name] (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-säure [German] [ACD/IUPAC Name] (1R,2R,3R)-3-Hydroxy-2-((E)-(3S)-3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid 212-017-2 [EINECS] 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl}heptanoic acid 7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl}heptansäure [German] Acide (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-én-1-oïque [French] [ACD/IUPAC Name] acide 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-én-1-yl]-5-oxocyclopentyl}heptanoïque [French] Alprostadil [USAN] [Wiki] Alprostadil Prostoglandin E1 alprostadilum [Latin] [INN] Caverject [Wiki] Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)- [ACD/Index Name] Prostaglandin E1 Prostaglandine E (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoate (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoic acid (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid (11α,13E,15S)-11,15-DIHYDROXY-9-OXOPROST-13-ENOIC ACID (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoate (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoic acid (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoate (13E)-(15S)-11α,15-Dihydroxy-9-oxoprost-13-enoate (13e)-(15S)-11α,15-dihydroxy-9-oxoprost-13-enoic acid (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoic acid (13E,15S)-11α,15-dihydroxy-9-oxoprost-13-en-1-oic acid 11,15-Dihydroxy-9-oxoprost-13-en-1-oate [ACD/IUPAC Name] 11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (ACD/Name 4.0) 119314-69-1 [RN] 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid 2061617 [Beilstein] 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoate 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-keto-cyclopentyl]enanthic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-keto-cyclopentyl]enanthic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]heptanoic acid 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoic acid 745-65-3 [RN] 9-oxo-11?,15S-dihydroxy-prost-13E-en-1-oic acid 9-oxo-11R,15S-dihydroxy-13E-prostaenoic acid 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid 9-Oxo-11α,15S-dihydroxyprost-13E-en-1-oic acid Alista Alprostadil (JP15/USP/INN) Alprostadil® Alprostadil®|MR-256|prostaglandin E1 Alprostadilum Alprox-TD Befar Befar; Caverject; Edex; Muse; Prostin VR BPBio1_001293 BSPBio_001175 BSPBio_001488 Caverject impulse cGMP Alprostadil Edex FemLife Femprox GY4569800 IDI1_033958 Liple Lipoprost Liprostin l-Prostaglandin E1 MFCD00077860 [MDL number] Minprog MLS000758964 Muse NCGC00025234-02 NCGC00025234-03 PGE1 PGE1 PGE-1 PGE1 | Prostaglandin E1 | Prestwick2_001018 Prestwick3_001018 Prink Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)- Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, homopolymer prostaglandin E1 Prostaglandin E1; PGE1 Prostaglandin E1;Edex;Muse;Liprostin;Caverject ProstaglandinE1 Prostandin Prostavasin Prostin VR Prostin VR pediatric (TN) Prostivas SMP2_000271 SMR000112594 Sugiran Topiglan Toxic solid, organic, n.o.s. (Alprostadil) UN 2811 UN2811 UNII-F5TD010360 Viridal

Molecular Structure

Structure of Alprostadil CAS 745-65-3

Structure of Alprostadil CAS 745-65-3

SMILES

CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

StdInChI

InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

StdInChIKey

GMVPRGQOIOIIMI-DWKJAMRDSA-N

Molecular Formula

C20H33O5

Molecular Weight

353.4736

EINECS

212-017-2

Beilstein Registry Number

5294062

MDL Number

MFCD00077860

Properties

Appearance

White or pale yellow needles

Melting Point

115～116℃

Flash Point

103 °C

Safety Data

Symbol

exclamation-mark-jpgexclamation-mark-jpg GHS06, GHS08

Signal Word

Danger

Hazard Statements

H301-H361

Precautionary Statements

P281-P301 + P310

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RIDADR

UN 2811 6.1 / PGIII

RTECS

GY4569800

Specifications and Other Information of Our Alprostadil CAS 745-65-3

Standard

EP9.2

Identification Methods

HNMR/HPLC

Assay

95%~102%

Specific Optical Rotation

-70°~ -61.6°

Water

0.5%max

Residue on Ignition

0.5%max

Related substance/h3>

Impurity A

1.5%max

Impurity B

0.5%max

Any other impurity

0.9%max

Impurity number

1%max

Total Impurities

1.5%max

Residual solvents

Ethanol

5000ppm max

Acetone

5000ppm max

Dichloromethane

600ppm max

n-Hexane

290ppm max

Ethyl acetate

5000ppm max

n-Heptane

5000ppm max

Storage

Stored at 2-8 ° for long time, sealed and away from light.

Application

Commonly used in diabetic neuropathy, myocardial infarction, thrombotic vasculitis, arteriosclerosis obliterans, central retinal vein thrombosis.

Links

This product is developed by our RandD company Caming Pharmaceutical Ltd(http://www.caming.com/), and here is the corresponding linkhttp://www.caming.com/alprostadil-cas-745-65-3/

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    andD purpose. It may be toxic or hazardous, and should be handled only by qualified individuals trained in laboratory procedures. The buyer will be responsible to warn and inform any person that may be in contact with the product of the potential risks and hazards, as well as to ensure that purchase, use and disposal of the product comply with local laws and regulations.