Alprostadil CAS 745-65-3

Iden­ti­fi­ca­tion Prop­er­ties Safe­ty Data Spec­i­fi­ca­tions and Oth­er Information Links

Iden­ti­fi­ca­tion

CAS Number

745-65-3

Name

Alprostadil

Syn­onyms

(-)-Prostaglandin E1 (11a,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid [ACD/IUPAC Name] (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-säure [Ger­man] [ACD/IUPAC Name] (1R,2R,3R)-3-Hydroxy-2-((E)-(3S)-3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid 212-017-2 [EINECS] 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl}heptanoic acid 7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl}heptansäure [Ger­man] Acide (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-én-1-oïque [French] [ACD/IUPAC Name] acide 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-én-1-yl]-5-oxocyclopentyl}heptanoïque [French] Alprostadil [USAN] [Wiki] Alprostadil Pros­tog­landin E1 alprostadilum [Latin] [INN] Caver­ject [Wiki] Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)- [ACD/​Index Name] Prostaglandin E1 Prostaglan­dine E (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoate (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoic acid (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid (11α,13E,15S)-11,15-DIHY­DROXY-9-OXO­PROST-13-ENOIC ACID (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoate (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoic acid (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoate (13E)-(15S)-11α,15-Dihydroxy-9-oxoprost-13-enoate (13e)-(15S)-11α,15-dihydroxy-9-oxoprost-13-enoic acid (13E)-(15S)-11-α,15-dihydroxy-9-oxoprost-13-enoic acid (13E,15S)-11α,15-dihydroxy-9-oxoprost-13-en-1-oic acid 11,15-Dihydroxy-9-oxoprost-13-en-1-oate [ACD/IUPAC Name] 11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (ACD/​Name 4.0) 119314-69-1 [RN] 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid 2061617 [Beil­stein] 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoate 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-keto-cyclopentyl]enanthic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-keto-cyclopentyl]enanthic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]heptanoic acid 7-[5-((1E)(3S)-3-hydrox­y­oct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoic acid 745-65-3 [RN] 9-oxo-11?,15S-dihydroxy-prost-13E-en-1-oic acid 9-oxo-11R,15S-dihydroxy-13E-prostaenoic acid 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid 9-Oxo-11α,15S-dihydroxyprost-13E-en-1-oic acid Alista Alprostadil (JP15/USP/INN) Alprostadil® Alprostadil®|MR-256|prostaglandin E1 Alprostadilum Alprox-TD Befar Befar ; Caver­ject ; Edex ; Muse ; Prostin VR BPBio1_​001293 BSPBio_​001175 BSPBio_​001488 Caver­ject impulse cGMP Alprostadil Edex Fem­Life Fem­prox GY4569800 IDI1_033958 Liple Lipoprost Liprostin l-Prostaglandin E1 MFCD00077860 [MDL num­ber] Min­prog MLS000758964 Muse NCGC00025234-02 NCGC00025234-03 PGE1 PGE1 PGE-1 PGE1 | Prostaglandin E1 | Prestwick2_​001018 Prestwick3_​001018 Prink Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)- Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, homopoly­mer prostaglandin E1 Prostaglandin E1 ; PGE1 Prostaglandin E1;Edex;Muse;Liprostin;Caverject ProstaglandinE1 Pro­standin Prostavasin Prostin VR Prostin VR pedi­atric (TN) Pros­ti­vas SMP2_000271 SMR000112594 Sugi­ran Top­iglan Tox­ic sol­id, organ­ic, n.o.s. (Alprostadil) UN 2811 UN2811 UNII-F5T­D010360 Viri­dal

Mol­e­c­u­lar Structure

SMILES

CCC­CC[[email protected]@H](/C=C/[[email protected]]1[[email protected]@H](CC(=O)[[email protected]@H]1CCCCCCC(=O)O)O)O

Std­InChI

InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

Std­InChIKey

GMVPRGQOIOI­I­­MI-DWK­­JAM­RD­SA-N

Mol­e­c­u­lar Formula

C20H33O5

Mol­e­c­u­lar Weight

353.4736

EINECS

212-017-2

Beil­stein Reg­istry Number

5294062

MDL Number

MFCD00077860

Prop­er­ties

Appear­ance

White or pale yel­low nee­dles

Melt­ing Point

115～116℃

Flash Point

103 °C

Safe­ty Data

Sym­bol

GHS06, GHS08

Sig­nal Word

Dan­ger

Haz­ard Statements

H301-H361

Pre­cau­tion­ary Statements

P281-P301 + P310

Per­son­al Pro­tec­tive Equipment

dust mask type N95 (US), Eye­shields, Faceshields, Gloves

RIDADR

UN 2811 6.1 / PGI­II

RTECS

GY4569800

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Alprostadil CAS 745-65-3

Stan­dard

EP9.2

Iden­ti­fi­ca­tion Methods

HNMR/HPLC

Assay

95%~102%

Spe­cif­ic Opti­cal Rotation

-70°~ -61.6°

Water

0.5%max

Residue on Ignition

0.5%max

Relat­ed substance/​h3>

Impu­ri­ty A

1.5%max

Impu­ri­ty B

0.5%max

Any oth­er impurity

0.9%max

Impu­ri­ty number

1%max

Total Impu­ri­ties

1.5%max

Resid­ual solvents

Ethanol

5000ppm max

Ace­tone

5000ppm max

Dichloromethane

600ppm max

n-Hexa­­ne

290ppm max

Eth­yl acetate

5000ppm max

n-Hep­­­tane

5000ppm max

Stor­age

Stored at 2-8 ° for long time, sealed and away from light.

Appli­ca­tion

Com­mon­ly used in dia­bet­ic neu­ropa­thy, myocar­dial infarc­tion, throm­bot­ic vas­culi­tis, arte­rioscle­ro­sis oblit­er­ans, cen­tral reti­nal vein throm­bo­sis.

Links

This prod­uct is devel­oped by our RandD com­pa­ny Cam­ing Phar­ma­ceu­ti­cal Ltd(http://​www​.cam​ing​.com/), and here is the cor­re­spond­ing linkhttp://​www​.cam​ing​.com/​a​l​p​r​o​s​t​a​d​i​l​-​c​a​s​-​7​4​5​-​6​5​-3/

Quick Inquiry

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