Guanosine3′,5′-cyclicmonophosphatesodiumsalt CAS 40732-48-7

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• Prop­er­ties
• Safe­ty Data
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Iden­ti­fi­ca­tion

CAS Number

40732-48-7

Name

Guanosine3′,5′-cyclicmonophosphatesodiumsalt

Syn­onyms

(4aR,6R,7R,7aS) 2-Oxyde de 6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytétrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate et de sodi­um [French] [ACD/IUPAC Name]
255-056-0 [EINECS]
3′,5′-cGMP-Na
3′,5′-Cyclic GMP monosodi­um salt
40732-48-7 [RN]
6H-Purin-6-one, 2-amino-3,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodi­um salt (1:1) [ACD/​Index Name]
cGMP
Cyclic GMP
Cyclic GMP sodi­um salt
Guano­sine 3′,5′-cyclophosphate monosodi­um salt
MFCD00038424 [MDL num­ber]
Natrium-(4aR,6R,7R,7aS)-6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olat-2-oxid [Ger­man] [ACD/IUPAC Name]
Sodi­um (4aR,6R,7R,7aS)-6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide [ACD/IUPAC Name]
sodi­um 3′,5′-cyclic gmp anion
SODI­UM GUANO­SINE CYCLIC MONOPHOS­PHATE
,5ʹ
[40732-48-7] [RN]
3′,5′-cyclic Guano­sine monophos­phate
3′,5′-cGMP-Na
3′,5′-Cyclic GMP monosodi­um salt
cyclic 3′,?5′-?(hydrogen phos­phate) guano­sine, monosodi­um salt
Cyclic GMP sodi­um
Cyclic GMP, G-3,5-MP, cGMP, Na
-cyclic Monophos­phate, Sodi­um Salt – CAS 40732-48-7 – Cal­biochem
Guano­sine 3ʹ
Guano­sine 3ʹ,5ʹ-cyclic Monophos­phate, Sodi­um Salt – CAS 40732-48-7 – Cal­biochem
Guano­sine 3′,5′-Cyclic Monophos­phate Sodi­um Salt
Guano­sine 3’5’-cyclic Monophos­phate, Sodi­um Salt
Guano­sine 3′,5′-cyclic monophos­phate sodi­um salt
Guano­sine 3′,5′-cyclophosphate monosodi­um salt
Guano­sine 3’5′-cyclic Monophos­phate, Sodi­um Salt
Guanosine-3′:5′-cyclic monophos­phate monosodi­um salt
Guanosine3:5-cyclicmonophosphatesodiumsalt
GUANOSINE3′:5′-CYCLICMONOPHOSPHATESODIUMSALT
sodi­um (4aR,6R,7R,7aS)-6-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2??-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate

SMILES

c1nc2c(n1[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)[O-])O)[nH]c(nc2=O)N.[Na+]

Std­InChI

InChI=1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Std­InChIKey

KMPIYXN­ER­OUNOG-GWTDSMLYSA-M

Mol­e­c­u­lar Formula

C₁₀H₁₁N₅NaO₇P

Mol­e­c­u­lar Weight

367.187

MDL Number

MFCD00038424

Prop­er­ties

Appear­ance

White pow­der

Safe­ty Data

Sym­bol

Sig­nal Word

Warn­ing

WGK Germany

3

MSDS Download

Spec­i­fi­ca­tions and Oth­er Infor­ma­tion of Our Guanosine3′,5′-cyclicmonophosphatesodiumsalt CAS 40732-48-7

Puri­ty

99% min

Loss on Drying

≤7.0%

EmM UV-vis spec­trum, dry basis PH 7.0

14.08

Shelf Life

1 year

Stor­age

-20℃, sealed well and away from light

Known Appli­ca­tion

Sodi­um Guanosine-3′,5′-Cyclic Monophos­phate (cGMP-Na) has sev­er­al impor­tant appli­ca­tions in bio­chem­istry, phar­ma­col­o­gy, and biotechnology. 

1. Sig­nal Trans­duc­tion Research

• cGMP acts as an intra­cel­lu­lar sec­ond mes­sen­ger, play­ing a crit­i­cal role in var­i­ous bio­log­i­cal sig­nal trans­duc­tion process­es, such as smooth mus­cle relax­ation, vasodi­la­tion, and neur­al signaling.
• It is wide­ly used to study guany­late cyclase activ­i­ty and cGMP-depen­­dent sig­nal­ing pathways.

2. Phar­ma­co­log­i­cal Studies

• Used to inves­ti­gate the effects of drugs tar­get­ing cGMP-relat­ed path­ways, such as treat­ments for hyper­ten­sion, erec­tile dys­func­tion (e.g., mech­a­nisms of phos­pho­di­esterase-5 inhibitors), and car­dio­vas­cu­lar diseases.
• Aids in new drug devel­op­ment and the eval­u­a­tion of drug effects on cGMP-relat­ed processes.

3. Enzy­mol­o­gy Research

• Serves as a sub­strate for cGMP-depen­­dent pro­tein kinas­es and phos­pho­di­esteras­es, enabling stud­ies of enzyme mech­a­nisms and their reg­u­la­to­ry functions.

4. Cel­lu­lar and Mol­e­c­u­lar Biology

• Facil­i­tates research on cGMP’s role in cell pro­lif­er­a­tion, dif­fer­en­ti­a­tion, and apoptosis.
• Applied in cel­lu­lar mod­els or tis­sue cul­ture exper­i­ments to explore sig­nal­ing path­way regulation.

Gen­er­al View of Documents

Links

This prod­uct is devel­oped by our R&D com­pa­ny Ulcho Bio­chem­i­cal Lim­it­ed (http://​www​.ulcho​.com/).

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