Nafamostat mesylate CAS 82956-11-4

Nafamostat mesylate CAS 82956-11-4

Identification

CAS Number

82956-11-4

Name

Nafamostat mesylate

Synonyms

1D2T74921W
4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate
6-Carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate methanesulfonate (1:2) [ACD/IUPAC Name]
6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate methanesulfonate (1:2)
82956-11-4 [RN]
Acide méthanesulfonique – 4-carbamimidamidobenzoate de 6-carbamimidoyl-2-naphtyle (2:1) [French] [ACD/IUPAC Name]
Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, methanesulfonate (1:2) [ACD/Index Name]
DG2736000
Methansulfonsäure –6-carbamimidoyl-2-naphthyl-4-carbamimidamidobenzoat (2:1) [German] [ACD/IUPAC Name]
MFCD00941430 [MDL number]
Nafamostat mesylate [USAN]
(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate;methanesulfonic acid
[6-[4-[[amino(azaniumyl)methylidene]amino]benzoyl]oxynaphthalene-2-carboximidoyl]azanium and methanesulfonate
[82956-11-4]
4-[(aminoiminomethyl)amino]-6-(aminoiminomethyl)-2-naphthalenyl ester-benzoic acid, dimethanesulfonate
6-[amino(imino)methyl]-2-naphthyl 4-{[amino(imino)methyl]amino}benzoate dimethanesulfonate
6-amidino-2-naphthyl 4-(amidinoamino)benzoate, methanesulfonic acid, methanesulfonic acid
6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate
6-Amidino-2-naphthyl p-guanidinobenzoate, dimethanesulfonate
6-carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate methanesulfonate(1:2)
6-CARBAMIMIDOYLNAPHTHALEN-2-YL 4-CARBAMIMIDAMIDOBENZOATE; BIS(METHANESULFONIC ACID)
6-carbamimidoylnaphthalen-2-yl 4-guanidinobenzoate dimethanesulfonate
AMINO({[4-({[6-(AMMONIOMETHANIMIDOYL)NAPHTHALEN-2-YL]OXY}CARBONYL)PHENYL]IMINO})METHANAMINIUM DIMESYLATE
BENZOIC ACID, 4-((AMINOIMINOMETHYL)AMINO)-, 6-(AMINOIMINOMETHYL)-2-NAPHTHALENYL
Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate
benzoic acid, 4-[(aminoiminomethyl)amino], 6-(aminoiminomethyl)-2-naphthalenyl ester, methanesulfonate (1:2)
Coahibitor
Coahibitor;FUT-175;Futhan
Futhan
Futhan, FUT-175
Nafamostat (mesylate)
Nafamostat dimethanesulfonate
Nafamostat Mesilate
Nafamostat Mesylate(FUT-175)
Nafamostat Mesylate,FUT-175,Futhan
nafamostatmesylate
nafamstat mesilate
QA-7529
Ronastat [Trade name]
UNII:1D2T74921W
UNII-1D2T74921W

SMILES

CS(=O)(=O)O.CS(=O)(=O)O.c1cc(ccc1C(=O)Oc2ccc3cc(ccc3c2)C(=N)N)NC(=N)N

StdInChI

InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;21-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);21H3,(H,2,3,4)

StdInChIKey

SRXKIZXIRHMPFW-UHFFFAOYSA-N

Molecular Formula

C21H25N5O8S2

Molecular Weight

539.582

MDL Number

MFCD00941430

Properties

Appearance

White powder

Melting Point

259-261°C

Safety Data

Symbol

health hazard jpg - Nafamostat mesylate CAS 82956-11-4GHS08

Signal Word

Warning

Hazard statements

H361fd

Precautionary Statements

P281

Personal Protective Equipment

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RIDADR 

NONH for all modes of transport

WGK Germany

nwg

RTECS 

DG2736000

Specifications and Other Information of Our Nafamostat mesylate CAS 82956-11-4

Identification Methods

HPLC

Purity

99% min

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Often used as a protease inhibitor. Can strongly inhibit membrane proteases, dermal release enzymes, plasmin, fibrin and the classical pathways Clr-, Cls- and other trypsin-like serinase proteases. Chemicalbook white-bound trypsin has the same inhibitory effect as free trypsin. It is used to improve acute conditions such as acute pancreatitis, acute exacerbation of chronic pancreatitis, postoperative acute pancreatitis, acute pancreatitis after pancreatography, and traumatic pancreatitis. Recent studies have shown good therapeutic effects on new coronaviruses.

This product is developed by our R&D company Caming Pharmaceutical Ltd(http://www.caming.com/), and here is the corresponding linkhttp://www.caming.com/nafamostat-mesylate-cas-82956-11-4/

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