Bimatoprost CAS 155206-00-1

Identification Properties Safety Data Specifications andamp; Other Information Links

Identification

CAS Number

155206-00-1

Name

Bimatoprost

Synonyms

(5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamid [German] [ACD/IUPAC Name] (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide [ACD/IUPAC Name] (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phényl-1-pentén-1-yl]cyclopentyl}-N-éthyl-5-hepténamide [French] [ACD/IUPAC Name] (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5Z)- [ACD/Index Name] bimatoprost [French] [INN] bimatoprost [Spanish] [INN] Bimatoprost [USAN] [Wiki] bimatoprostum [Latin] [INN] Lumigan [Trade name] биматопрост [Russian] [INN] بيماتوبروست [Arabic] [INN] 贝美前列素 [Chinese] [INN] (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]cyclopentyl]-N-ethyl-hept-5-enamide [155206-00-1] 155206-00-1 [RN] 267244-98-4 [RN] 5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (5Z)- 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-(1α(Z),2β(1E,3S*),3α,5α))- AGN 192024|LS-181817|Lumigan® Lumigan (TN) Lumigan® Lumigan; Latisse; AGN 192024; bimatoprostum; Lumigan (TN); AC1NSJUW; AGN-192024; UNII-QXS94885MZ MFCD03411999 [MDL number] UNII-QXS94885MZ

Molecular Structure

SMILES

CCNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCc2ccccc2)O)O)O

StdInChI

InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1

StdInChIKey

AQOKCDNYWBIDND-FTOWTWDKSA-N

Molecular Formula

C25H37NO4

Molecular Weight

415.57

Properties

Appearance

White powder

Safety Data

Personal Protective Equipment

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RIDADR

NONH for all modes of transport

WGK Germany

3

MSDS

MSDS of Bimatoprost CAS 155206-00-1

Specifications and Other Information of Our Bimatoprost CAS 155206-00-1

Standard

Enterprise standard

Certificate

GMP

Identification Methods

HNMR/HPLC

Purity

99.5% min

Specific Optical Rotation

+33.0-+37.0°

Heavy Metals

10ppmmax

Residue on Ignition

0.1%max

Single Impurity

0.1%max

Total Impurities

0.5%max

Storage

Store at the 2-8℃

Adding proportion for reference

0.03%/100ml

Application

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It has also been used and prescribed off-label to lengthen eyelashes.

General View of Documents

IR Test Conditions

1. Bimatoprost: Potassium bromide = 1:100 2. It is better to add Bimatoprost for tabetted after baked potassium bromide is cooled down completely to avoid the effect to Bimatoprost by high temperature 3. Pay attention to temperature and humidity of the test environment.

Links

This product is developed by our RD company Caming Pharmaceutical Ltd(http://www.caming.com/), and here is the corresponding linkhttp://www.caming.com/bimatoprost-cas-155206-00-1/

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